flumazenil has been researched along with Convulsions, Grand Mal in 5 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The influence of flumazenil on seizures induced by pentylenetetrazol (PTZ) was studied in rats aged 7, 12, 18, 25, and 90 days." | 3.68 | Anticonvulsant activity of flumazenil in rats during ontogenetic development. ( Kubová, H; Mares, P; Rathouská, J; Vorlícek, J, 1993) |
| "Physical dependence was produced in the rat by exposure to continuous release of diazepam from silastic capsule implants (recrystallized diazepam) or by dosing through a gastric fistula." | 1.29 | Precipitated abstinence in the diazepam-dependent rat. ( Martin, WR; Sloan, JW; Wala, EP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nassiri-Asl, M | 1 |
| Shariati-Rad, S | 1 |
| Zamansoltani, F | 1 |
| Scollo-Lavizzari, G | 1 |
| Martin, WR | 1 |
| Sloan, JW | 1 |
| Wala, EP | 1 |
| Rathouská, J | 1 |
| Kubová, H | 1 |
| Mares, P | 1 |
| Vorlícek, J | 1 |
| Mordel, A | 1 |
| Winkler, E | 1 |
| Almog, S | 1 |
| Tirosh, M | 1 |
| Ezra, D | 1 |
5 other studies available for flumazenil and Convulsions, Grand Mal
| Article | Year |
|---|---|
Anticonvulsive effects of intracerebroventricular administration of rutin in rats.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clon | 2008 |
The anticonvulsant effect of the benzodiazepine antagonist, Ro 15-1788: an EEG study in 4 cases.
Topics: Action Potentials; Adult; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Drug Interactions; El | 1984 |
Precipitated abstinence in the diazepam-dependent rat.
Topics: Animals; Behavior, Animal; Brain; Diazepam; Drug Implants; Epilepsy, Tonic-Clonic; Female; Flumazeni | 1993 |
Anticonvulsant activity of flumazenil in rats during ontogenetic development.
Topics: Aging; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Female; F | 1993 |
Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.
Topics: Adult; Clonazepam; Diazepam; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Flumazenil; Humans; Imip | 1992 |