Page last updated: 2024-10-27

flumazenil and Combat Disorders

flumazenil has been researched along with Combat Disorders in 4 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Combat Disorders: Neurotic reactions to unusual, severe, or overwhelming military stress.

Research Excerpts

ExcerptRelevanceReference
"Flumazenil is a relatively pure benzodiazepine/GABAA antagonist with limited intrinsic activity."2.68Effects of the benzodiazepine antagonist flumazenil in PTSD. ( Bremner, JD; Charney, DS; Heninger, GR; Krystal, JH; Nagy, LM; Nicolaou, AL; Randall, PK, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujita, M1
Southwick, SM2
Denucci, CC1
Zoghbi, SS1
Dillon, MS1
Baldwin, RM1
Bozkurt, A1
Kugaya, A1
Verhoeff, NP1
Seibyl, JP1
Innis, RB2
Randall, PK1
Bremner, JD2
Krystal, JH1
Nagy, LM1
Heninger, GR1
Nicolaou, AL1
Charney, DS2
Coupland, NJ1
Lillywhite, A1
Bell, CE1
Potokar, JP1
Nutt, DJ1
Staib, L1
Zoghbi, S1

Trials

3 trials available for flumazenil and Combat Disorders

ArticleYear
Central type benzodiazepine receptors in Gulf War veterans with posttraumatic stress disorder.
    Biological psychiatry, 2004, Jul-15, Volume: 56, Issue:2

    Topics: Adult; Combat Disorders; Female; Flumazenil; Humans; Iodine Radioisotopes; Life Change Events; Male;

2004
Effects of the benzodiazepine antagonist flumazenil in PTSD.
    Biological psychiatry, 1995, Sep-01, Volume: 38, Issue:5

    Topics: Anxiety Disorders; Arousal; Combat Disorders; Double-Blind Method; Flumazenil; GABA Modulators; GABA

1995
A pilot controlled study of the effects of flumazenil in posttraumatic stress disorder.
    Biological psychiatry, 1997, May-01, Volume: 41, Issue:9

    Topics: Adult; Arousal; Combat Disorders; Double-Blind Method; Female; Flumazenil; GABA Modulators; Humans;

1997

Other Studies

1 other study available for flumazenil and Combat Disorders

ArticleYear
Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder.
    The American journal of psychiatry, 2000, Volume: 157, Issue:7

    Topics: Adult; Brief Psychiatric Rating Scale; Combat Disorders; Flumazenil; Hippocampus; Humans; Iodine Rad

2000