flumazenil has been researched along with Cognition Disorders in 15 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cognitive impairment causes morbidity in schizophrenia and could be due to abnormalities of cortical interneurons using the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)." | 9.12 | Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia. ( Bullmore, E; Fletcher, P; Kamath, S; McKenna, P; Menzies, L; Ooi, C; Stephenson, C; Suckling, J, 2007) |
| "Cognitive impairment causes morbidity in schizophrenia and could be due to abnormalities of cortical interneurons using the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)." | 5.12 | Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia. ( Bullmore, E; Fletcher, P; Kamath, S; McKenna, P; Menzies, L; Ooi, C; Stephenson, C; Suckling, J, 2007) |
| " Group B patients (20) were treated by tapering of oxazepam dosage (from 120 mg) and with saline solution (as placebo) instead of FLU for 8 days." | 2.70 | Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study. ( Brewer, C; Gerra, G; Giusti, F; Moi, G; Zaimovic, A, 2002) |
| "Intracranial meningiomas are the most common types of neoplasms that cause mental disorders." | 1.40 | Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection. ( Ideguchi, M; Ishihara, H; Iwanaga, H; Koizumi, H; Nomura, S; Oka, F; Sadahiro, H; Shirao, S; Suehiro, E; Suzuki, M; Yoneda, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abiko, K | 1 |
| Shiga, T | 1 |
| Katoh, C | 1 |
| Hirata, K | 1 |
| Kuge, Y | 1 |
| Kobayashi, K | 1 |
| Ikeda, S | 1 |
| Ikoma, K | 1 |
| Koizumi, H | 1 |
| Ideguchi, M | 1 |
| Iwanaga, H | 1 |
| Shirao, S | 1 |
| Sadahiro, H | 1 |
| Oka, F | 1 |
| Suehiro, E | 1 |
| Yoneda, H | 1 |
| Ishihara, H | 1 |
| Nomura, S | 1 |
| Suzuki, M | 1 |
| Chida, K | 2 |
| Ogasawara, K | 2 |
| Suga, Y | 2 |
| Saito, H | 1 |
| Kobayashi, M | 2 |
| Yoshida, K | 2 |
| Otawara, Y | 1 |
| Ogawa, A | 2 |
| Ochalski, PG | 1 |
| Fellows-Mayle, W | 1 |
| Hsieh, LB | 1 |
| Srinivas, R | 1 |
| Okonkwo, DO | 1 |
| Dixon, CE | 1 |
| Adelson, PD | 1 |
| Aso, K | 1 |
| Terasaki, K | 1 |
| Tsushina, E | 1 |
| Pappatà, S | 1 |
| Varrone, A | 1 |
| Vicidomini, C | 1 |
| Milan, G | 1 |
| De Falco, C | 1 |
| Sansone, V | 1 |
| Iavarone, A | 1 |
| Comerci, M | 1 |
| Loré, E | 1 |
| Panico, MR | 1 |
| Quarantelli, M | 1 |
| Postiglione, A | 1 |
| Salvatore, M | 1 |
| Mathieu, A | 1 |
| Vacca, A | 1 |
| Serra, A | 1 |
| Cauli, A | 1 |
| Piga, M | 2 |
| Porru, G | 1 |
| Marrosu, F | 1 |
| Sanna, G | 1 |
| Kawai, N | 1 |
| Maeda, Y | 1 |
| Kudomi, N | 1 |
| Yamamoto, Y | 1 |
| Nishiyama, Y | 1 |
| Tamiya, T | 1 |
| Yamauchi, H | 1 |
| Gerra, G | 1 |
| Zaimovic, A | 1 |
| Giusti, F | 1 |
| Moi, G | 1 |
| Brewer, C | 1 |
| Menzies, L | 1 |
| Ooi, C | 1 |
| Kamath, S | 1 |
| Suckling, J | 1 |
| McKenna, P | 1 |
| Fletcher, P | 1 |
| Bullmore, E | 1 |
| Stephenson, C | 1 |
| Wicks, P | 1 |
| Turner, MR | 1 |
| Abrahams, S | 1 |
| Hammers, A | 1 |
| Brooks, DJ | 1 |
| Leigh, PN | 1 |
| Goldstein, LH | 1 |
| Amodio, P | 1 |
| Marchetti, P | 1 |
| Del Piccolo, F | 1 |
| Beghi, A | 1 |
| Comacchio, F | 1 |
| Carraro, P | 1 |
| Campo, G | 1 |
| Baruzzo, L | 1 |
| Marchiori, C | 1 |
| Gatta, A | 1 |
| Mielke, R | 1 |
| Hilker, R | 1 |
| Weber-Luxenburger, G | 1 |
| Kessler, J | 1 |
| Heiss, WD | 1 |
| Preston, GC | 1 |
| Ward, C | 1 |
| Lines, CR | 1 |
| Poppleton, P | 1 |
| Haigh, JR | 1 |
| Traub, M | 1 |
3 trials available for flumazenil and Cognition Disorders
| Article | Year |
|---|---|
Intravenous flumazenil versus oxazepam tapering in the treatment of benzodiazepine withdrawal: a randomized, placebo-controlled study.
Topics: Adult; Anti-Anxiety Agents; Antidotes; Benzodiazepines; Blood Pressure; Cognition Disorders; Diagnos | 2002 |
Effects of gamma-aminobutyric acid-modulating drugs on working memory and brain function in patients with schizophrenia.
Topics: Adult; Brain; Cerebral Cortex; Cognition Disorders; Double-Blind Method; Flumazenil; GABA Modulators | 2007 |
The effect of flumazenil on subclinical psychometric or neurophysiological alterations in cirrhotic patients: a double-blind placebo-controlled study.
Topics: Cognition; Cognition Disorders; Double-Blind Method; Evoked Potentials, Auditory, Brain Stem; Female | 1997 |
12 other studies available for flumazenil and Cognition Disorders
| Article | Year |
|---|---|
Relationship between intelligence quotient (IQ) and cerebral metabolic rate of oxygen in patients with neurobehavioural disability after traumatic brain injury.
Topics: Adult; Brain Injuries, Traumatic; Cognition Disorders; Female; Flumazenil; Humans; Intelligence; Int | 2018 |
Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection.
Topics: Aged; Aged, 80 and over; Brain; Brain Neoplasms; Cell Survival; Cerebrovascular Circulation; Cogniti | 2014 |
Postoperative cortical neural loss associated with cerebral hyperperfusion and cognitive impairment after carotid endarterectomy: 123I-iomazenil SPECT study.
Topics: Adult; Aged; Analysis of Variance; Carotid Stenosis; Cerebral Cortex; Cerebrovascular Circulation; C | 2009 |
Flumazenil administration attenuates cognitive impairment in immature rats after controlled cortical impact.
Topics: Animals; Brain; Brain Chemistry; Brain Injuries; Cognition Disorders; Disease Models, Animal; Dose-R | 2010 |
Postcarotid endarterectomy improvement in cognition is associated with resolution of crossed cerebellar hypoperfusion and increase in 123I-iomazenil uptake in the cerebral cortex: a SPECT study.
Topics: Adult; Afferent Pathways; Aged; Carotid Artery, Internal; Carotid Stenosis; Cerebellum; Cerebral Cor | 2010 |
SPECT imaging of GABA(A)/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Case-Control Studies; Cerebrovascular Circulation; Cognition Disorders; Fem | 2010 |
Defective cerebral gamma-aminobutyric acid-A receptor density in patients with systemic lupus erythematosus and central nervous system involvement. An observational study.
Topics: Adult; Central Nervous System; Cerebral Cortex; Cerebrovascular Circulation; Cognition Disorders; El | 2010 |
Focal neuronal damage in patients with neuropsychological impairment after diffuse traumatic brain injury: evaluation using ¹¹C-flumazenil positron emission tomography with statistical image analysis.
Topics: Adult; Brain; Brain Injuries; Brain Mapping; Carbon Isotopes; Cognition; Cognition Disorders; Female | 2010 |
[Ischemic cortical neuronal damage and cognitive impairments in atherosclerotic occlusive disease of the major cerebral artery: a PET study].
Topics: Aged; Brain Ischemia; Carbon Radioisotopes; Carotid Artery Diseases; Cerebral Cortex; Cognition Diso | 2011 |
Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Carbon Radioisotopes; Cognition Disorders; Female; Fluma | 2008 |
Early-onset cerebellar ataxia (EOCA) with retained reflexes: reduced cerebellar benzodiazepine-receptor binding, progressive metabolic and cognitive impairment.
Topics: Adult; Blood Glucose; Brain Mapping; Cerebellum; Cognition Disorders; Diagnosis, Differential; Energ | 1998 |
Scopolamine and benzodiazepine models of dementia: cross-reversals by Ro 15-1788 and physostigmine.
Topics: Acoustic Stimulation; Adult; Anti-Anxiety Agents; Attention; Cognition Disorders; Dementia; Disease | 1989 |