flumazenil has been researched along with Charcot-Marie-Tooth Disease in 10 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Charcot-Marie-Tooth Disease: A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)
| Excerpt | Relevance | Reference |
|---|---|---|
| "HMSNR affects only patients with Roma origin, similar to the better known HMSN type Lom clarified earlier." | 1.43 | HSMNR belongs to the most frequent types of hereditary neuropathy in the Czech Republic and is twice more frequent than HMSNL. ( Haberlová, J; Laštůvková, J; Mazanec, R; Šafka Brožková, D; Seeman, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gabrikova, D | 1 |
| Mistrik, M | 1 |
| Bernasovska, J | 1 |
| Bozikova, A | 1 |
| Behulova, R | 1 |
| Tothova, I | 1 |
| Macekova, S | 1 |
| Fernández-Ramos, JA | 1 |
| López-Laso, E | 1 |
| Camino-León, R | 1 |
| Gascón-Jiménez, FJ | 1 |
| Jiménez-González, MD | 1 |
| Šafka Brožková, D | 2 |
| Haberlová, J | 1 |
| Mazanec, R | 1 |
| Laštůvková, J | 1 |
| Seeman, P | 3 |
| Paulasová Schwabová, J | 1 |
| Neupauerová, J | 1 |
| Sabová, J | 1 |
| Krůtová, M | 1 |
| Peřina, V | 1 |
| Trková, M | 1 |
| Laššuthová, P | 1 |
| Sevilla, T | 2 |
| Martínez-Rubio, D | 1 |
| Márquez, C | 1 |
| Paradas, C | 1 |
| Colomer, J | 2 |
| Jaijo, T | 1 |
| Millán, JM | 2 |
| Palau, F | 2 |
| Espinós, C | 2 |
| Guergueltcheva, V | 1 |
| Tournev, I | 1 |
| Bojinova, V | 1 |
| Hantke, J | 1 |
| Litvinenko, I | 1 |
| Ishpekova, B | 1 |
| Shmarov, A | 1 |
| Petrova, J | 1 |
| Jordanova, A | 1 |
| Kalaydjieva, L | 2 |
| Gooding, R | 1 |
| Angelicheva, D | 1 |
| King, RH | 1 |
| Guillén-Navarro, E | 1 |
| Parman, Y | 1 |
| Nascimento, A | 1 |
| Conill, J | 1 |
| Echaniz-Laguna, A | 1 |
| Degos, B | 1 |
| Bonnet, C | 1 |
| Latour, P | 1 |
| Hamadouche, T | 1 |
| Lévy, N | 1 |
| Leheup, B | 1 |
| Claramunt, R | 1 |
| Lupo, V | 1 |
| Cuesta, A | 1 |
| Vílchez, JJ | 1 |
| Baránková, L | 1 |
| Sisková, D | 1 |
| Hühne, K | 1 |
| Vyhnálková, E | 1 |
| Sakmaryová, I | 1 |
| Bojar, M | 1 |
| Rautenstrauss, B | 1 |
10 other studies available for flumazenil and Charcot-Marie-Tooth Disease
| Article | Year |
|---|---|
Founder mutations in NDRG1 and HK1 genes are common causes of inherited neuropathies among Roma/Gypsies in Slovakia.
Topics: Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Consanguinity; Female; Founder Effect; Genes, Rece | 2013 |
[Experience in molecular diagnostic in hereditary neuropathies in a pediatric tertiary hospital].
Topics: Adolescent; Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Connexins; Co | 2015 |
HSMNR belongs to the most frequent types of hereditary neuropathy in the Czech Republic and is twice more frequent than HMSNL.
Topics: Adolescent; Adult; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Czech Republic; Female; Fou | 2016 |
HMSN Lom in 12 Czech patients, with one unusual case due to uniparental isodisomy of chromosome 8.
Topics: Adult; Age of Onset; Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Chro | 2017 |
Genetics of the Charcot-Marie-Tooth disease in the Spanish Gypsy population: the hereditary motor and sensory neuropathy-Russe in depth.
Topics: Adolescent; Adult; Cell Cycle Proteins; Charcot-Marie-Tooth Disease; Child; DNA Mutational Analysis; | 2013 |
Early clinical and electrophysiologic features of the two most common autosomal recessive forms of Charcot-Marie-Tooth disease in the Roma (Gypsies).
Topics: Adolescent; Bulgaria; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Diagnosis, Differential; | 2006 |
Clinical spectrum of CMT4C disease in patients homozygous for the p.Arg1109X mutation in SH3TC2.
Topics: Adolescent; Adult; Age of Onset; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Female; Found | 2006 |
NDRG1-linked Charcot-Marie-Tooth disease (CMT4D) with central nervous system involvement.
Topics: Adolescent; Brain; Cell Cycle Proteins; Central Nervous System; Charcot-Marie-Tooth Disease; Deafnes | 2007 |
The p.R1109X mutation in SH3TC2 gene is predominant in Spanish Gypsies with Charcot-Marie-Tooth disease type 4.
Topics: Charcot-Marie-Tooth Disease; Chromosome Mapping; Chromosomes, Human, Pair 10; Chromosomes, Human, Pa | 2007 |
A 71-nucleotide deletion in the periaxin gene in a Romani patient with early-onset slowly progressive demyelinating CMT.
Topics: Age of Onset; Base Sequence; Charcot-Marie-Tooth Disease; Child, Preschool; Demyelinating Diseases; | 2008 |