flumazenil has been researched along with Central Nervous System Diseases in 4 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ivermectin is considered a very safe drug; however, there are reports of toxic effects in particularly sensitive populations or due to accidental overdose." | 1.37 | Central and peripheral neurotoxic effects of ivermectin in rats. ( Nedeljkovic, JT; Trailovic, SM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hulse, G | 1 |
| Kelty, E | 1 |
| Hood, S | 1 |
| Norman, A | 1 |
| Basso, MR | 1 |
| Reece, AS | 1 |
| Trailovic, SM | 1 |
| Nedeljkovic, JT | 1 |
| Ferrer, A | 1 |
| Civeira, E | 1 |
| Lopez, P | 1 |
| Loren, B | 1 |
| Koeppe, RA | 1 |
| Raffel, DM | 1 |
| Snyder, SE | 1 |
| Ficaro, EP | 1 |
| Kilbourn, MR | 1 |
| Kuhl, DE | 1 |
2 reviews available for flumazenil and Central Nervous System Diseases
| Article | Year |
|---|---|
Novel Indications for Benzodiazepine Antagonist Flumazenil in GABA Mediated Pathological Conditions of the Central Nervous System.
Topics: Animals; Central Nervous System; Central Nervous System Diseases; Flumazenil; GABA Antagonists; gamm | 2015 |
The use of antidotes in the management of central nervous system depression.
Topics: Antidotes; Benzodiazepines; Central Nervous System Depressants; Central Nervous System Diseases; Eme | 1997 |
1 trial available for flumazenil and Central Nervous System Diseases
| Article | Year |
|---|---|
Dual-[11C]tracer single-acquisition positron emission tomography studies.
Topics: Brain; Carbon Radioisotopes; Central Nervous System Diseases; Computer Simulation; Flumazenil; GABA | 2001 |
1 other study available for flumazenil and Central Nervous System Diseases
| Article | Year |
|---|---|
Central and peripheral neurotoxic effects of ivermectin in rats.
Topics: Adjuvants, Anesthesia; Animals; Antidotes; Antiparasitic Agents; Atropine; Central Nervous System Di | 2011 |