flumazenil has been researched along with Brain Neoplasms in 10 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed to determine whether the exacerbated upper limb motor-sensory deficits are mediated through benzodiazepine sites by demonstrating reversibility by flumazenil in patients with gliomas in eloquent areas." | 7.91 | Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas. ( Gelb, AW; Han, R; Hui, X; Lin, N; Zhang, K, 2019) |
| " This study aimed to determine whether the exacerbated upper limb motor-sensory deficits are mediated through benzodiazepine sites by demonstrating reversibility by flumazenil in patients with gliomas in eloquent areas." | 3.91 | Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas. ( Gelb, AW; Han, R; Hui, X; Lin, N; Zhang, K, 2019) |
| "Intracranial meningiomas are the most common types of neoplasms that cause mental disorders." | 1.40 | Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection. ( Ideguchi, M; Ishihara, H; Iwanaga, H; Koizumi, H; Nomura, S; Oka, F; Sadahiro, H; Shirao, S; Suehiro, E; Suzuki, M; Yoneda, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murata, H | 1 |
| Yokoyama, A | 1 |
| Hara, T | 1 |
| Lin, N | 1 |
| Han, R | 1 |
| Hui, X | 1 |
| Zhang, K | 1 |
| Gelb, AW | 1 |
| Koizumi, H | 1 |
| Ideguchi, M | 1 |
| Iwanaga, H | 1 |
| Shirao, S | 1 |
| Sadahiro, H | 1 |
| Oka, F | 1 |
| Suehiro, E | 1 |
| Yoneda, H | 1 |
| Ishihara, H | 1 |
| Nomura, S | 1 |
| Suzuki, M | 1 |
| Horky, LL | 1 |
| Treves, ST | 1 |
| Ito, H | 2 |
| Goto, R | 2 |
| Koyama, M | 2 |
| Kawashima, R | 2 |
| Ono, S | 2 |
| Sato, K | 2 |
| Fukuda, H | 2 |
| Richardson, MP | 1 |
| Hammers, A | 1 |
| Brooks, DJ | 1 |
| Duncan, JS | 1 |
| Knudsen, L | 1 |
| Cold, GE | 1 |
| Holdgård, HO | 1 |
| Johansen, UT | 1 |
| Jensen, S | 1 |
| Ferrarese, C | 1 |
| Appollonio, I | 1 |
| Frigo, M | 1 |
| Gaini, SM | 1 |
| Piolti, R | 1 |
| Frattola, L | 1 |
| Tan, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Imaging After Stereotactic Radiosurgery for Brain Metastases or Primary Tumor Can Hybrid PET-MRI Differentiate Between Radiation Effects and Disease ?[NCT03068520] | 140 participants (Anticipated) | Interventional | 2017-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for flumazenil and Brain Neoplasms
| Article | Year |
|---|---|
PET and SPECT in brain tumors and epilepsy.
Topics: Brain; Brain Neoplasms; Cell Proliferation; Dideoxynucleosides; Epilepsy; Flumazenil; Fluorodeoxyglu | 2011 |
1 trial available for flumazenil and Brain Neoplasms
| Article | Year |
|---|---|
Effects of flumazenil on cerebral blood flow and oxygen consumption after midazolam anaesthesia for craniotomy.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Brain Neoplas | 1991 |
8 other studies available for flumazenil and Brain Neoplasms
| Article | Year |
|---|---|
Titration of flumazenil during awake craniotomy.
Topics: Brain Neoplasms; Craniotomy; Flumazenil; Humans; Wakefulness | 2023 |
Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas.
Topics: Adult; Brain Neoplasms; Female; Flumazenil; GABA Modulators; Glioma; Humans; Hypnotics and Sedatives | 2019 |
Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection.
Topics: Aged; Aged, 80 and over; Brain; Brain Neoplasms; Cell Survival; Cerebrovascular Circulation; Cogniti | 2014 |
A simple method for the quantification of benzodiazepine receptors using iodine-123 iomazenil and single-photon emission tomography.
Topics: Brain; Brain Neoplasms; Cerebrovascular Disorders; Computer Simulation; Dementia; Flumazenil; Humans | 1996 |
A method for the quantification of benzodiazepine receptors by using 123I-iomazenil and SPECT with one scan and one blood sampling.
Topics: Adult; Aged; Autoradiography; Brain; Brain Neoplasms; Cerebrovascular Disorders; Computer Simulation | 1997 |
Benzodiazepine-GABA(A) receptor binding is very low in dysembryoplastic neuroepithelial tumor: a PET study.
Topics: Adult; Amygdala; Brain Neoplasms; Carbon Radioisotopes; Cerebral Cortex; Epilepsy; Female; Flumazeni | 2001 |
Benzodiazepine receptors and diazepam-binding inhibitor in human cerebral tumors.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Diazepam Binding Inhibitor; Female; Fl | 1989 |
Perianal melanoma with a BRAF gene mutation in a young Portuguese Roma native.
Topics: Adult; Anal Gland Neoplasms; Brain Neoplasms; Fatal Outcome; Humans; Lung Neoplasms; Male; Melanoma; | 2016 |