flumazenil has been researched along with Body Weight in 24 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 7.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "The benzodiazepine receptor antagonist flumazenil reduces anxiety-like behavior and sensitization of anxiety-like behavior in various models of ethanol withdrawal in rodents." | 7.74 | The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress. ( Angel, RA; Breese, GR; Knapp, DJ; Navarro, M; Overstreet, DH, 2007) |
| " In the present study, we investigated the possible involvement of GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice." | 3.74 | Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. ( Kumar, A; Singh, A, 2008) |
| "The benzodiazepine receptor antagonist flumazenil reduces anxiety-like behavior and sensitization of anxiety-like behavior in various models of ethanol withdrawal in rodents." | 3.74 | The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress. ( Angel, RA; Breese, GR; Knapp, DJ; Navarro, M; Overstreet, DH, 2007) |
| "Changes in body weight (BW) in female rats treated for 5 weeks (wk) with weekly subcutaneous implantation of silastic capsules containing different benzodiazepines (BZs): diazepam (DZ) 90, 180, 360 and 540 mg wk-1; nordiazepam (ND) 600 mg wk-1; oxazepam (OX) 600 mg wk-1 and flunitrazepam (FN) 540 mg wk-1 and in male rats exposed to DZ (540 mg wk-1) were evaluated herein." | 3.70 | The effect of chronic benzodiazepines exposure on body weight in rats. ( Jing, X; Sloan, JW; Wala, EP, 1998) |
| "Treatment with melatonin (5 mg/kg and 10 mg/kg, ip) significantly improved locomotor activity, weight loss and antianxiety effect as compared with control (sleep-deprived)." | 1.35 | Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. ( Kumar, A; Singh, A, 2009) |
| "When PK 11195 was administered weekly (5 weeks), rather than daily, tolerance did not develop in either sex." | 1.31 | The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats. ( Holtman, JR; Jing, X; Sloan, JW; Wala, EP, 2000) |
| "Sex differences, and the influence of drug dosage and additional upper airway obstruction were studied in midazolam-induced breathing patterns and sedation in 30 healthy volunteers (8 males and 22 females)." | 1.29 | Differences in midazolam-induced breathing patterns in healthy volunteers. ( Haji, A; Ito, Y; Masuda, A; Shakunaga, K; Shibuya, N; Wakasugi, M, 1995) |
| " In both rats and cats, neither acute nor chronic administration of benzodiazepines or their antagonists altered the retinal functions, as determined by the electroretinogram." | 1.28 | Benzodiazepines and the mammalian retina. I. Autoradiographic localisation of receptor sites and the lack of effect on the electroretinogram. ( Ikeda, H; Robbins, J, 1989) |
| "When clonazepam was finally withdrawn, a self-limiting abstinence syndrome was observed in all dogs, consisting of behavioral alterations (listlessness, wet dog shakes, dorsal recumbency), tremor, a severe clonic-tonic seizure in 1 case, hyperthermia, and weight loss." | 1.27 | Physical dependence on clonazepam in dogs. ( Frey, HH; Scherkl, R, 1986) |
| "Buspirone-treated rats gain weight during withdrawal, suggesting that this novel anxiolytic should lack dependence liability in man." | 1.27 | Lack of withdrawal signs of dependence following cessation of treatment or Ro-15,1788 administration to rats chronically treated with buspirone. ( Eison, MS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (29.17) | 18.7374 |
| 1990's | 9 (37.50) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, A | 2 |
| Kumar, A | 2 |
| Knapp, DJ | 3 |
| Overstreet, DH | 3 |
| Breese, GR | 3 |
| Navarro, M | 2 |
| Wills, TA | 1 |
| Angel, RA | 2 |
| Masuda, A | 1 |
| Haji, A | 1 |
| Wakasugi, M | 1 |
| Shibuya, N | 1 |
| Shakunaga, K | 1 |
| Ito, Y | 1 |
| Pesce, ME | 1 |
| Acevedo, X | 1 |
| Pinardi, G | 1 |
| Miranda, HF | 1 |
| Atsmon, J | 1 |
| Oaknin, S | 1 |
| Laudon, M | 1 |
| Laschiner, S | 1 |
| Gavish, M | 1 |
| Dagan, Y | 1 |
| Zisapel, N | 1 |
| Jing, X | 4 |
| Wala, EP | 3 |
| Sloan, JW | 4 |
| Wala, E | 1 |
| Holtman, JR | 3 |
| Milliken, B | 1 |
| Weerts, EM | 1 |
| Griffiths, RR | 1 |
| Pankaj, V | 1 |
| Brain, PF | 1 |
| Chan, AW | 1 |
| Leong, FW | 1 |
| Langan, MC | 1 |
| Schanley, DL | 1 |
| Penetrante, ML | 1 |
| Van Miert, AS | 1 |
| Koot, M | 1 |
| Van Duin, CT | 1 |
| Robbins, J | 1 |
| Ikeda, H | 1 |
| Shibata, S | 1 |
| Yamashita, K | 1 |
| Yamamoto, E | 1 |
| Ozaki, T | 1 |
| Ueki, S | 1 |
| Scherkl, R | 1 |
| Frey, HH | 1 |
| Gallager, DW | 1 |
| Heninger, K | 1 |
| Heninger, G | 1 |
| Eison, MS | 1 |
| Brcanski, J | 1 |
| Jović-Vraneš, A | 1 |
| Marinković, J | 1 |
| Favre, D | 1 |
| Gasparovic, J | 1 |
| Raslová, K | 1 |
| Basistová, Z | 1 |
| Zacharová, M | 1 |
| Wsólová, L | 1 |
| Avdicová, M | 1 |
| Blazícek, P | 1 |
| Lietava, J | 1 |
| Siváková, D | 1 |
| Malá, H | 1 |
| Machová, J | 1 |
24 other studies available for flumazenil and Body Weight
| Article | Year |
|---|---|
Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice.
Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Catalase; Dose-Response Relationship, Drug; Flumaze | 2008 |
Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Fem | 2009 |
Baclofen blocks expression and sensitization of anxiety-like behavior in an animal model of repeated stress and ethanol withdrawal.
Topics: Alcohol Drinking; Animals; Anxiety; Baclofen; Body Weight; Central Nervous System Depressants; Diet; | 2007 |
Repeated lipopolysaccharide (LPS) or cytokine treatments sensitize ethanol withdrawal-induced anxiety-like behavior.
Topics: Analysis of Variance; Animals; Antidotes; Anxiety; Behavior, Animal; Body Weight; Cytokines; Disease | 2008 |
The amygdala regulates the antianxiety sensitization effect of flumazenil during repeated chronic ethanol or repeated stress.
Topics: Alcohol Drinking; Alcoholism; Amygdala; Animals; Anxiety; Behavior, Animal; Body Weight; Disease Mod | 2007 |
Differences in midazolam-induced breathing patterns in healthy volunteers.
Topics: Abdominal Muscles; Adult; Body Height; Body Weight; Conscious Sedation; Female; Flumazenil; Humans; | 1995 |
Gender differences in diazepam withdrawal syndrome in mice.
Topics: Animals; Body Weight; Castration; Diazepam; Disease Models, Animal; Estrogens; Female; Flumazenil; I | 1994 |
Reciprocal effects of chronic diazepam and melatonin on brain melatonin and benzodiazepine binding sites.
Topics: Animals; Body Weight; Brain; Cerebral Cortex; Diazepam; Flumazenil; Flunitrazepam; Kinetics; Male; M | 1996 |
The effect of chronic benzodiazepines exposure on body weight in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationshi | 1998 |
Diazepam-treated female rats: flumazenil- and PK 11195-induced withdrawal in the hippocampus CA1.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationship, Drug; Electroenceph | 1998 |
Zolpidem self-injection with concurrent physical dependence under conditions of long-term continuous availability in baboons.
Topics: Animals; Behavior, Animal; Body Weight; Flumazenil; Food; GABA Modulators; Hypnotics and Sedatives; | 1998 |
Precipitated withdrawal in the substantia nigra in diazepam-dependent female rats.
Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Electroencephalography; Female; Flumazenil; GAB | 1999 |
The pharmacodynamics of PK 11195 in diazepam-dependent male and female rats.
Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Body Weight; Brain; Diazepam; Female; Flumazeni | 2000 |
Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in Swiss mice--II. Antagonists.
Topics: Animals; Behavior, Animal; Benzodiazepines; Body Weight; Female; Flumazenil; Growth; Male; Mice; Pos | 1991 |
The ability of chlordiazepoxide to maintain ethanol tolerance and dependence.
Topics: Animals; Body Temperature; Body Weight; Chlordiazepoxide; Diet; Drug Tolerance; Ethanol; Flumazenil; | 1991 |
Appetite-modulating drugs in dwarf goats, with special emphasis on benzodiazepine-induced hyperphagia and its antagonism by flumazenil and RO 15-3505.
Topics: Animals; Anti-Anxiety Agents; Appetite Regulation; Azepines; Benzodiazepines; Benzodiazepinones; Bod | 1989 |
Benzodiazepines and the mammalian retina. I. Autoradiographic localisation of receptor sites and the lack of effect on the electroretinogram.
Topics: Animals; Benzodiazepines; Body Weight; Cats; Flumazenil; Flunitrazepam; Flurazepam; Membrane Potenti | 1989 |
Effects of benzodiazepine and GABA antagonists on anticonflict effects of antianxiety drugs injected into the rat amygdala in a water-lick suppression test.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Behavior, Animal; Body Weight; Carbolines; Conflict, Psychol | 1989 |
Physical dependence on clonazepam in dogs.
Topics: Animals; Benzodiazepinones; Body Temperature; Body Weight; Clonazepam; Dogs; Female; Flumazenil; Mal | 1986 |
Periodic benzodiazepine antagonist administration prevents benzodiazepine withdrawal symptoms in primates.
Topics: Animals; Behavior, Animal; Body Weight; Diazepam; Drug Administration Schedule; Flumazenil; Macaca m | 1986 |
Lack of withdrawal signs of dependence following cessation of treatment or Ro-15,1788 administration to rats chronically treated with buspirone.
Topics: Animals; Body Weight; Buspirone; Diazepam; Flumazenil; Food Deprivation; Male; Pyrimidines; Rats; Ra | 1986 |
Social determinants of malnutrition among Serbian children aged <5 years: ethnic and regional disparities.
Topics: Body Weight; Child Nutrition Disorders; Child, Preschool; Cross-Sectional Studies; Ethnicity; Female | 2014 |
Effect of C677T methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine levels in ethnic groups.
Topics: Adult; Body Height; Body Mass Index; Body Weight; Ethnicity; Female; Gene Frequency; Genotype; Hemat | 2004 |
Birthweight of newborn Romanies and their physical development during the school age period.
Topics: Adolescent; Birth Weight; Body Height; Body Weight; Child; Czechoslovakia; Ethnicity; Female; Humans | 1978 |