Page last updated: 2024-10-27

flumazenil and Benign Neoplasms, Brain

flumazenil has been researched along with Benign Neoplasms, Brain in 10 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Research Excerpts

ExcerptRelevanceReference
" This study aimed to determine whether the exacerbated upper limb motor-sensory deficits are mediated through benzodiazepine sites by demonstrating reversibility by flumazenil in patients with gliomas in eloquent areas."7.91Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas. ( Gelb, AW; Han, R; Hui, X; Lin, N; Zhang, K, 2019)
" This study aimed to determine whether the exacerbated upper limb motor-sensory deficits are mediated through benzodiazepine sites by demonstrating reversibility by flumazenil in patients with gliomas in eloquent areas."3.91Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas. ( Gelb, AW; Han, R; Hui, X; Lin, N; Zhang, K, 2019)
"Intracranial meningiomas are the most common types of neoplasms that cause mental disorders."1.40Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection. ( Ideguchi, M; Ishihara, H; Iwanaga, H; Koizumi, H; Nomura, S; Oka, F; Sadahiro, H; Shirao, S; Suehiro, E; Suzuki, M; Yoneda, H, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Murata, H1
Yokoyama, A1
Hara, T1
Lin, N1
Han, R1
Hui, X1
Zhang, K1
Gelb, AW1
Koizumi, H1
Ideguchi, M1
Iwanaga, H1
Shirao, S1
Sadahiro, H1
Oka, F1
Suehiro, E1
Yoneda, H1
Ishihara, H1
Nomura, S1
Suzuki, M1
Horky, LL1
Treves, ST1
Ito, H2
Goto, R2
Koyama, M2
Kawashima, R2
Ono, S2
Sato, K2
Fukuda, H2
Richardson, MP1
Hammers, A1
Brooks, DJ1
Duncan, JS1
Knudsen, L1
Cold, GE1
HoldgÄrd, HO1
Johansen, UT1
Jensen, S1
Ferrarese, C1
Appollonio, I1
Frigo, M1
Gaini, SM1
Piolti, R1
Frattola, L1
Tan, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Imaging After Stereotactic Radiosurgery for Brain Metastases or Primary Tumor Can Hybrid PET-MRI Differentiate Between Radiation Effects and Disease ?[NCT03068520]140 participants (Anticipated)Interventional2017-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for flumazenil and Benign Neoplasms, Brain

ArticleYear
PET and SPECT in brain tumors and epilepsy.
    Neurosurgery clinics of North America, 2011, Volume: 22, Issue:2

    Topics: Brain; Brain Neoplasms; Cell Proliferation; Dideoxynucleosides; Epilepsy; Flumazenil; Fluorodeoxyglu

2011

Trials

1 trial available for flumazenil and Benign Neoplasms, Brain

ArticleYear
Effects of flumazenil on cerebral blood flow and oxygen consumption after midazolam anaesthesia for craniotomy.
    British journal of anaesthesia, 1991, Volume: 67, Issue:3

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Anesthesia, Intravenous; Brain Neoplas

1991

Other Studies

8 other studies available for flumazenil and Benign Neoplasms, Brain

ArticleYear
Titration of flumazenil during awake craniotomy.
    Journal of anesthesia, 2023, Volume: 37, Issue:1

    Topics: Brain Neoplasms; Craniotomy; Flumazenil; Humans; Wakefulness

2023
Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas.
    Anesthesiology, 2019, Volume: 131, Issue:1

    Topics: Adult; Brain Neoplasms; Female; Flumazenil; GABA Modulators; Glioma; Humans; Hypnotics and Sedatives

2019
Cognitive dysfunction might be improved in association with recovered neuronal viability after intracranial meningioma resection.
    Brain research, 2014, Jul-29, Volume: 1574

    Topics: Aged; Aged, 80 and over; Brain; Brain Neoplasms; Cell Survival; Cerebrovascular Circulation; Cogniti

2014
A simple method for the quantification of benzodiazepine receptors using iodine-123 iomazenil and single-photon emission tomography.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:7

    Topics: Brain; Brain Neoplasms; Cerebrovascular Disorders; Computer Simulation; Dementia; Flumazenil; Humans

1996
A method for the quantification of benzodiazepine receptors by using 123I-iomazenil and SPECT with one scan and one blood sampling.
    Annals of nuclear medicine, 1997, Volume: 11, Issue:2

    Topics: Adult; Aged; Autoradiography; Brain; Brain Neoplasms; Cerebrovascular Disorders; Computer Simulation

1997
Benzodiazepine-GABA(A) receptor binding is very low in dysembryoplastic neuroepithelial tumor: a PET study.
    Epilepsia, 2001, Volume: 42, Issue:10

    Topics: Adult; Amygdala; Brain Neoplasms; Carbon Radioisotopes; Cerebral Cortex; Epilepsy; Female; Flumazeni

2001
Benzodiazepine receptors and diazepam-binding inhibitor in human cerebral tumors.
    Annals of neurology, 1989, Volume: 26, Issue:4

    Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Diazepam Binding Inhibitor; Female; Fl

1989
Perianal melanoma with a BRAF gene mutation in a young Portuguese Roma native.
    BMJ case reports, 2016, Feb-15, Volume: 2016

    Topics: Adult; Anal Gland Neoplasms; Brain Neoplasms; Fatal Outcome; Humans; Lung Neoplasms; Male; Melanoma;

2016