flumazenil has been researched along with Benign Essential Tremor in 3 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using (11)C-flumazenil and PET, we calculated the distribution volume, an index of availability of benzodiazepine receptor sites of the GABA(A) complex, in a group of 8 patients with bilateral essential tremor, as compared with 11 healthy controls." | 7.76 | GABAergic dysfunction in essential tremor: an 11C-flumazenil PET study. ( Boecker, H; Brooks, DJ; Ceballos-Baumann, AO; Liedtke, C; Miederer, I; Miederer, M; Sprenger, T; Wagner, KJ; Weindl, A, 2010) |
| " Only non-impairing doses were used to evaluate for anti-tremor efficacy in the harmaline model, which was assessed in wildtype and α6 subunit knockout littermates." | 4.31 | Search for Novel Therapies for Essential Tremor Based on Positive Modulation of α6-Containing GABA ( Ernst, M; Handforth, A; Singh, RP; Treven, M, 2023) |
| "We measured the tremor clinical rating scale score and acquired DASB and Flumazenil PET scans in 10 patients who presented with essential tremor at different stages of clinical severity." | 3.78 | Gaba and serotonin molecular neuroimaging in essential tremor: a clinical correlation study. ( Figueiras, FP; Gironell, A; Gispert, JD; Herance, JR; Pagonabarraga, J; Pascual-Sedano, B; Trampal, C, 2012) |
| "Using (11)C-flumazenil and PET, we calculated the distribution volume, an index of availability of benzodiazepine receptor sites of the GABA(A) complex, in a group of 8 patients with bilateral essential tremor, as compared with 11 healthy controls." | 3.76 | GABAergic dysfunction in essential tremor: an 11C-flumazenil PET study. ( Boecker, H; Brooks, DJ; Ceballos-Baumann, AO; Liedtke, C; Miederer, I; Miederer, M; Sprenger, T; Wagner, KJ; Weindl, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Handforth, A | 1 |
| Singh, RP | 1 |
| Treven, M | 1 |
| Ernst, M | 1 |
| Boecker, H | 1 |
| Weindl, A | 1 |
| Brooks, DJ | 1 |
| Ceballos-Baumann, AO | 1 |
| Liedtke, C | 1 |
| Miederer, M | 1 |
| Sprenger, T | 1 |
| Wagner, KJ | 1 |
| Miederer, I | 1 |
| Gironell, A | 1 |
| Figueiras, FP | 1 |
| Pagonabarraga, J | 1 |
| Herance, JR | 1 |
| Pascual-Sedano, B | 1 |
| Trampal, C | 1 |
| Gispert, JD | 1 |
3 other studies available for flumazenil and Benign Essential Tremor
| Article | Year |
|---|---|
Search for Novel Therapies for Essential Tremor Based on Positive Modulation of α6-Containing GABA
Topics: Animals; Essential Tremor; Flumazenil; gamma-Aminobutyric Acid; Harmaline; Humans; Ketamine; Mice; M | 2023 |
GABAergic dysfunction in essential tremor: an 11C-flumazenil PET study.
Topics: Aged; Brain; Cerebellum; Essential Tremor; Female; Flumazenil; GABA Modulators; gamma-Aminobutyric A | 2010 |
Gaba and serotonin molecular neuroimaging in essential tremor: a clinical correlation study.
Topics: Aged; Cerebellum; Essential Tremor; Female; Flumazenil; gamma-Aminobutyric Acid; Humans; Image Proce | 2012 |