flumazenil has been researched along with Apnea, Sleep in 2 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flumazenil is a selective benzodiazepine-antagonist." | 2.68 | Benzodiazepine receptor antagonist (flumazenil) does not affect sleep-related breathing disorders. ( Köhler, D; Schönhofer, B, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schönhofer, B | 1 |
| Köhler, D | 1 |
| Dhonneur, G | 1 |
| Combes, X | 1 |
| Leroux, B | 1 |
| Duvaldestin, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| TAP) Block in Morbid Obese Patients Undergoing Laparoscopic Gastric Bypass Surgery: A Prospective,Randomized, Blinded Study[NCT01075087] | 19 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
24 Hour total opioid consumption translated into IV morphine equivalents. (NCT01075087)
Timeframe: 24 hours
| Intervention | miligram IV morphine equivalents (Median) |
|---|---|
| Placebo | 13 |
| Active Comparator | 7.5 |
Quality of Recovery 40 Score at 24 hours postoperative. (NCT01075087)
Timeframe: 24 hours post operatively
| Intervention | units on scale 40 (low) - 200 (high) (Median) |
|---|---|
| Placebo | 170 |
| Active Comparator | 175.5 |
2 trials available for flumazenil and Apnea, Sleep
| Article | Year |
|---|---|
Benzodiazepine receptor antagonist (flumazenil) does not affect sleep-related breathing disorders.
Topics: Body Mass Index; Cross-Over Studies; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Human | 1996 |
Postoperative obstructive apnea.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Diaphragm; Electromyography; Flumazenil; GABA | 1999 |