Page last updated: 2024-10-27

flumazenil and Anterior Choroidal Artery Infarction

flumazenil has been researched along with Anterior Choroidal Artery Infarction in 20 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Research Excerpts

ExcerptRelevanceReference
" To determine whether viable neurones of low functional activity are represented in in vivo neuroreceptor imaging, we undertook experiments in gerbils with cerebral infarction, in which we examined histological changes and the results of dual-tracer in vivo autoradiography of glucose utilization with 14C-labelled deoxyglucose and benzodiazepine receptor binding with 123I-labelled Ro 16-0154."3.69A potential use of a 123I-labelled benzodiazepine receptor antagonist as a predictor of neuronal cell viability: comparisons with 14C-labelled 2-deoxyglucose autoradiography and histopathological examination. ( Fujita, M; Ikuta, F; Minoshima, S; Miyashita, K; Nakajima, T; Odano, I; Takahashi, N, 1995)
" We have evaluated by positron emission tomography the time course of changes in brain uptake in vivo of 11C-labeled PK 11195 and flumazenil (an antagonist of central benzodiazepine receptors) as indirect and direct markers of neuronal loss, respectively, after focal cerebral ischemia."3.68In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon. ( Baron, JC; Barré, L; Derlon, JM; MacKenzie, ET; Miyazawa, H; Sette, G; Tillet, I; Travère, JM; Young, AR, 1993)
"The porcine ET-1 model of cerebral ischemia is easier to implement then other large animal models of stroke, and performs similarly as long as CBF is monitored using CTP to prevent reperfusion."1.43Absolute Cerebral Blood Flow Infarction Threshold for 3-Hour Ischemia Time Determined with CT Perfusion and 18F-FFMZ-PET Imaging in a Porcine Model of Cerebral Ischemia. ( Cockburn, N; d'Esterre, CD; Kovacs, M; Lee, TY; Morrison, LB; Wright, EA, 2016)
"Two patients with subacute cerebral infarction underwent benzodiazepine receptor imaging using I-123-iomazenil and cerebral perfusion imaging with Tc-99m HMPAO and Tc-99m ECD."1.30Brain SPECT imaging using three different tracers in subacute cerebral infarction. ( Amano, T; Fukuuchi, Y; Hashimoto, J; Itoh, Y; Kubo, A; Nakamura, K; Sasaki, T, 1998)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (60.00)18.2507
2000's4 (20.00)29.6817
2010's2 (10.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Yamauchi, H1
Kagawa, S1
Kusano, K1
Ito, M1
Okuyama, C1
Hughes, JL1
Beech, JS1
Jones, PS1
Wang, D1
Menon, DK1
Aigbirhio, FI1
Fryer, TD1
Baron, JC2
Wright, EA1
d'Esterre, CD1
Morrison, LB1
Cockburn, N1
Kovacs, M1
Lee, TY1
Heiss, WD2
Müller, V1
Saur, D2
Klutmann, S1
Weiller, C2
Röther, J2
Clausen, M1
Dohmen, C1
Sobesky, J1
Kracht, L1
Bosche, B1
Staub, F1
Toyota, S1
Valentino, M1
Graf, R1
Abe, K1
Kashiwagi, Y1
Tokumura, M1
Hosoi, R1
Hatazawa, J2
Inoue, O1
Buchert, R1
Knab, R1
Odano, I1
Miyashita, K1
Minoshima, S1
Nakajima, T1
Fujita, M1
Takahashi, N2
Ikuta, F1
Sette, G1
Young, AR1
Miyazawa, H1
Tillet, I1
Barré, L1
Travère, JM1
Derlon, JM1
MacKenzie, ET1
Matsuda, H1
Tsuji, S1
Kuji, I1
Hisada, K1
Satoh, T1
Shimosegawa, E1
Okudera, T1
Inugami, A1
Ogawa, T1
Fujita, H1
Noguchi, K1
Kanno, I1
Miura, S1
Onishi, Y1
Yonekura, Y2
Tanaka, F1
Nishizawa, S1
Okazawa, H1
Ishizu, K1
Fujita, T1
Konishi, J1
Mukai, T1
Nakagawara, J1
Sperling, B1
Lassen, NA1
Takahashi, W1
Ohnuki, Y1
Ohta, T1
Hamano, H1
Yamamoto, M1
Shinohara, Y1
Sasaki, M1
Ichiya, Y1
Kuwabara, Y1
Yoshida, T1
Fukumura, T1
Masuda, K1
Hashimoto, J1
Sasaki, T1
Itoh, Y1
Nakamura, K1
Kubo, A1
Amano, T1
Fukuuchi, Y1
Ramírez-Moreno, JM1
Cordero, JA1
Durán-Herrera, C1
Makino, K1
Kamiyama, H1
Takamura, H1
Gotoh, S1
Kobayashi, N1
Tsuchida, T1
Sadato, N1
Yamamoto, K1
Ishii, Y1

Reviews

1 review available for flumazenil and Anterior Choroidal Artery Infarction

ArticleYear
The ischemic penumbra: how does tissue injury evolve?
    Annals of the New York Academy of Sciences, 2012, Volume: 1268

    Topics: Animals; Brain; Brain Edema; Brain Ischemia; Cats; Cerebral Infarction; Cerebrovascular Circulation;

2012

Trials

1 trial available for flumazenil and Anterior Choroidal Artery Infarction

ArticleYear
Experience with 123I-iomazenil SPECT in acute cerebral infarction.
    Nuclear medicine communications, 2002, Volume: 23, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Cerebral Infarction; Data Interpretation, Statistical; Female; Fluma

2002

Other Studies

18 other studies available for flumazenil and Anterior Choroidal Artery Infarction

ArticleYear
Neuronal Alterations in Secondary Thalamic Degeneration Due to Cerebral Infarction: A
    Stroke, 2022, Volume: 53, Issue:10

    Topics: Animals; Cerebral Arterial Diseases; Cerebral Infarction; Flumazenil; Humans; Oxygen; Positron-Emiss

2022
Early-stage
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020, Volume: 40, Issue:10

    Topics: Animals; Antigens, Nuclear; Cerebral Infarction; Female; Flumazenil; Immunohistochemistry; Infarctio

2020
Absolute Cerebral Blood Flow Infarction Threshold for 3-Hour Ischemia Time Determined with CT Perfusion and 18F-FFMZ-PET Imaging in a Porcine Model of Cerebral Ischemia.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; F

2016
Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis.
    Acta neurochirurgica. Supplement, 2003, Volume: 86

    Topics: Amino Acids; Animals; Brain Edema; Cats; Cerebral Infarction; Cerebrovascular Circulation; Flumazeni

2003
Discrepancy between cell injury and benzodiazepine receptor binding after transient middle cerebral artery occlusion in rats.
    Synapse (New York, N.Y.), 2004, Sep-15, Volume: 53, Issue:4

    Topics: Animals; Autoradiography; Benzazepines; Benzilates; Binding Sites; Binding, Competitive; Cerebral Co

2004
Iomazenil-single-photon emission computed tomography reveals selective neuronal loss in magnetic resonance-defined mismatch areas.
    Stroke, 2006, Volume: 37, Issue:11

    Topics: Adult; Aged; Cell Count; Cerebral Infarction; Female; Flumazenil; Follow-Up Studies; Humans; Magneti

2006
A potential use of a 123I-labelled benzodiazepine receptor antagonist as a predictor of neuronal cell viability: comparisons with 14C-labelled 2-deoxyglucose autoradiography and histopathological examination.
    Nuclear medicine communications, 1995, Volume: 16, Issue:6

    Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Cell Survival; Cerebral Infarction; Cerebrova

1995
In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon.
    Stroke, 1993, Volume: 24, Issue:12

    Topics: Animals; Brain Ischemia; Brain Mapping; Cerebral Infarction; Flumazenil; Isoquinolines; Macrophages;

1993
[Central type benzodiazepine receptor and cerebral blood flow in experimental chronic brain infarction--evaluation using a double-tracer autoradiography technique].
    Kaku igaku. The Japanese journal of nuclear medicine, 1993, Volume: 30, Issue:6

    Topics: Animals; Autoradiography; Brain; Cerebral Infarction; Cerebrovascular Circulation; Chronic Disease;

1993
Evaluation of cerebral infarction with iodine 123-iomazenil SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:12

    Topics: Aphasia, Broca; Aphasia, Wernicke; Brain; Cerebral Infarction; Cerebrovascular Circulation; Female;

1995
Delayed image of iodine-123 iomazenil as a relative map of benzodiazepine receptor binding: the optimal scan time.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:11

    Topics: Alzheimer Disease; Brain; Case-Control Studies; Cerebral Infarction; Computer Simulation; Dementia,

1996
Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil.
    Stroke, 1997, Volume: 28, Issue:1

    Topics: Aged; Cerebellum; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Female; Flumaze

1997
Mechanism of reduction of cortical blood flow in striatocapsular infarction: studies using [123I]iomazenil SPECT.
    NeuroImage, 1997, Volume: 6, Issue:2

    Topics: Aphasia; Basal Ganglia; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Female; F

1997
Benzodiazepine receptors in chronic cerebrovascular disease: comparison with blood flow and metabolism.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:11

    Topics: Brain; Cerebral Infarction; Cerebrovascular Circulation; Female; Flumazenil; Humans; Iodine Radioiso

1997
Brain SPECT imaging using three different tracers in subacute cerebral infarction.
    Clinical nuclear medicine, 1998, Volume: 23, Issue:5

    Topics: Adult; Brain; Cerebellum; Cerebral Infarction; Cerebrovascular Circulation; Cysteine; Female; Flumaz

1998
[Transitory comatose situation secondary to an infarction of the posterior circulation, reversed by naloxone?].
    Revista de neurologia, 1998, Volume: 26, Issue:154

    Topics: Adult; Brain Ischemia; Cerebral Infarction; Coma; Drug Therapy, Combination; Emergency Medical Servi

1998
Assessment of outcome by EC/IC bypass with 123I-iomazenil brain SPECT.
    Annals of nuclear medicine, 1999, Volume: 13, Issue:4

    Topics: Aged; Arterial Occlusive Diseases; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Arter

1999
Prediction of improvement of cerebral perfusion with I-123 iomazenil SPECT.
    Annals of nuclear medicine, 1999, Volume: 13, Issue:4

    Topics: Arterial Occlusive Diseases; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebral Arterial Di

1999