flumazenil has been researched along with Angelman Syndrome in 2 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
Angelman Syndrome: A syndrome characterized by multiple abnormalities, MENTAL RETARDATION, and movement disorders. Present usually are skull and other abnormalities, frequent infantile spasms (SPASMS, INFANTILE); easily provoked and prolonged paroxysms of laughter (hence happy); jerky puppetlike movements (hence puppet); continuous tongue protrusion; motor retardation; ATAXIA; MUSCLE HYPOTONIA; and a peculiar facies. It is associated with maternal deletions of chromosome 15q11-13 and other genetic abnormalities. (From Am J Med Genet 1998 Dec 4;80(4):385-90; Hum Mol Genet 1999 Jan;8(1):129-35)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asahina, N | 1 |
| Shiga, T | 1 |
| Egawa, K | 1 |
| Shiraishi, H | 1 |
| Kohsaka, S | 1 |
| Saitoh, S | 1 |
| Odano, I | 1 |
| Anezaki, T | 1 |
| Ohkubo, M | 1 |
| Yonekura, Y | 1 |
| Onishi, Y | 1 |
| Inuzuka, T | 1 |
| Takahashi, M | 1 |
| Tsuji, S | 1 |
2 other studies available for flumazenil and Angelman Syndrome
| Article | Year |
|---|---|
[(11)C]flumazenil positron emission tomography analyses of brain gamma-aminobutyric acid type A receptors in Angelman syndrome.
Topics: Adult; Angelman Syndrome; Brain; Case-Control Studies; Child; Female; Flumazenil; Humans; Imaging, T | 2008 |
Decrease in benzodiazepine receptor binding in a patient with Angelman syndrome detected by iodine-123 iomazenil and single-photon emission tomography.
Topics: Adult; Amphetamines; Angelman Syndrome; Brain; Cerebrovascular Circulation; Female; Flumazenil; Huma | 1996 |