flumazenil has been researched along with Amphetamine Abuse in 3 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients seeking treatment for methylamphetamine dependence must cope with drug cravings as they engage in psychosocial treatments." | 2.76 | A controlled trial of flumazenil and gabapentin for initial treatment of methylamphetamine dependence. ( Baron, M; Hanselka, LL; Urschel, HC, 2011) |
| "12mg/kg/infusion) were tested, producing an inverted U-shaped dose-response curve." | 1.43 | The differential effects of alprazolam and oxazepam on methamphetamine self-administration in rats. ( Goeders, NE; Guerin, GF; Spence, AL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spence, AL | 1 |
| Guerin, GF | 1 |
| Goeders, NE | 1 |
| Urschel, HC | 1 |
| Hanselka, LL | 1 |
| Baron, M | 1 |
| Ling, W | 1 |
| Shoptaw, S | 1 |
| Hillhouse, M | 1 |
| Bholat, MA | 1 |
| Charuvastra, C | 1 |
| Heinzerling, K | 1 |
| Chim, D | 1 |
| Annon, J | 1 |
| Dowling, PT | 1 |
| Doraimani, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-Blind, Placebo Controlled Trial of Prometa Pharmacotherapy for the Treatment of Methamphetamine Abuse[NCT00260481] | Phase 2/Phase 3 | 120 participants (Actual) | Interventional | 2006-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for flumazenil and Amphetamine Abuse
| Article | Year |
|---|---|
A controlled trial of flumazenil and gabapentin for initial treatment of methylamphetamine dependence.
Topics: Adolescent; Adult; Amines; Amphetamine-Related Disorders; Anticonvulsants; Behavior, Addictive; Cycl | 2011 |
Double-blind placebo-controlled evaluation of the PROMETA™ protocol for methamphetamine dependence.
Topics: Adult; Amines; Amphetamine-Related Disorders; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug | 2012 |
1 other study available for flumazenil and Amphetamine Abuse
| Article | Year |
|---|---|
The differential effects of alprazolam and oxazepam on methamphetamine self-administration in rats.
Topics: Alprazolam; Amphetamine-Related Disorders; Animals; Dose-Response Relationship, Drug; Flumazenil; Is | 2016 |