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flumazenil and Akinetic-Rigid Variant of Huntington Disease

flumazenil has been researched along with Akinetic-Rigid Variant of Huntington Disease in 5 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Research Excerpts

ExcerptRelevanceReference
"Flumazenil Kd was similar in the Huntington's disease group and the control group (11."1.31Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECT. ( Hasselbalch, SG; Knudsen, GM; Paulson, OB; Pinborg, LH; Sørensen, SA; Videbaek, C; Wagner, A, 2001)
"Flumazenil data were analyzed with a recently developed two-compartment, two-parameter tracer kinetic model."1.29Positron emission tomography measures of benzodiazepine receptors in Huntington's disease. ( Frey, KA; Holthoff, VA; Koeppe, RA; Kuhl, DE; Markel, DS; Penney, JB; Young, AB, 1993)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holthoff, VA1
Koeppe, RA1
Frey, KA2
Penney, JB1
Markel, DS1
Kuhl, DE1
Young, AB1
File, SE1
Mahal, A1
Mangiarini, L1
Bates, GP1
Künig, G1
Leenders, KL1
Sanchez-Pernaute, R1
Antonini, A1
Vontobel, P1
Verhagen, A1
Günther, I1
Pinborg, LH1
Videbaek, C1
Hasselbalch, SG1
Sørensen, SA1
Wagner, A1
Paulson, OB1
Knudsen, GM1
Suzuki, M1
Desmond, TJ1
Albin, RL1

Other Studies

5 other studies available for flumazenil and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Positron emission tomography measures of benzodiazepine receptors in Huntington's disease.
    Annals of neurology, 1993, Volume: 34, Issue:1

    Topics: Adult; Analysis of Variance; Brain; Carbon Radioisotopes; Female; Flumazenil; Humans; Huntington Dis

1993
Striking changes in anxiety in Huntington's disease transgenic mice.
    Brain research, 1998, Sep-14, Volume: 805, Issue:1-2

    Topics: Animals; Anxiety; Exploratory Behavior; Female; Flumazenil; Huntington Disease; Maze Learning; Mice;

1998
Benzodiazepine receptor binding in Huntington's disease: [11C]flumazenil uptake measured using positron emission tomography.
    Annals of neurology, 2000, Volume: 47, Issue:5

    Topics: Adult; Carbon Radioisotopes; Caudate Nucleus; Dopamine Antagonists; Female; Flumazenil; GABA Modulat

2000
Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECT.
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 70, Issue:5

    Topics: Adult; Female; Flumazenil; Humans; Huntington Disease; Iodine Radioisotopes; Male; Middle Aged; Rece

2001
Vesicular neurotransmitter transporters in Huntington's disease: initial observations and comparison with traditional synaptic markers.
    Synapse (New York, N.Y.), 2001, Sep-15, Volume: 41, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Animals; Autoradiography; Carrier Proteins; Choline O-Acetyltransfer

2001