flumazenil has been researched along with Affective Psychosis, Bipolar in 5 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "M, 385+/-44 fmol/mg ETE) and control (383+/-44 fmol/mg ETE) subjects, there was an increase in the density of [(3)H]flumazenil binding to the benzodiazepine binding site on the GABA(A) receptor in subjects with bipolar disorder (451+/-17 fmol/mg ETE; P<0." | 7.71 | A change in the density of [(3)H]flumazenil, but not [(3)H]muscimol binding, in Brodmann's Area 9 from subjects with bipolar disorder. ( Copolov, D; Dean, B; Keks, N; McLeod, M; Opeskin, K; Pavey, G, 2001) |
| "Postmortem CNS studies have suggested an uncoupling of the gamma-aminobutyric acid (GABA) and benzodiazepine binding sites on the hippocampal GABA(A) receptor in schizophrenia." | 3.73 | Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder. ( Dean, B; McLeod, M; Scarr, E, 2005) |
| "M, 385+/-44 fmol/mg ETE) and control (383+/-44 fmol/mg ETE) subjects, there was an increase in the density of [(3)H]flumazenil binding to the benzodiazepine binding site on the GABA(A) receptor in subjects with bipolar disorder (451+/-17 fmol/mg ETE; P<0." | 3.71 | A change in the density of [(3)H]flumazenil, but not [(3)H]muscimol binding, in Brodmann's Area 9 from subjects with bipolar disorder. ( Copolov, D; Dean, B; Keks, N; McLeod, M; Opeskin, K; Pavey, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dean, B | 2 |
| Scarr, E | 1 |
| McLeod, M | 2 |
| Pavey, G | 1 |
| Opeskin, K | 1 |
| Keks, N | 1 |
| Copolov, D | 1 |
| Schumacher, J | 1 |
| Kaneva, R | 3 |
| Jamra, RA | 1 |
| Diaz, GO | 1 |
| Ohlraun, S | 1 |
| Milanova, V | 3 |
| Lee, YA | 1 |
| Rivas, F | 1 |
| Mayoral, F | 1 |
| Fuerst, R | 1 |
| Flaquer, A | 1 |
| Windemuth, C | 1 |
| Gay, E | 1 |
| Sanz, S | 1 |
| González, MJ | 1 |
| Gil, S | 1 |
| Cabaleiro, F | 1 |
| del Rio, F | 1 |
| Perez, F | 1 |
| Haro, J | 1 |
| Kostov, C | 2 |
| Chorbov, V | 1 |
| Nikolova-Hill, A | 1 |
| Stoyanova, V | 3 |
| Onchev, G | 2 |
| Kremensky, I | 2 |
| Strauch, K | 1 |
| Schulze, TG | 1 |
| Nürnberg, P | 1 |
| Gaebel, W | 1 |
| Klimke, A | 1 |
| Auburger, G | 1 |
| Wienker, TF | 1 |
| Kalaydjieva, L | 3 |
| Propping, P | 1 |
| Cichon, S | 1 |
| Jablensky, A | 3 |
| Rietschel, M | 1 |
| Nöthen, MM | 1 |
| Angelicheva, D | 1 |
| MacGregor, S | 1 |
| Vladimirova, R | 1 |
| Aleksiev, S | 1 |
| Angelova, M | 1 |
| Loh, A | 1 |
| Hallmayer, J | 2 |
| Chakarova, CH | 1 |
| Nikolova, A | 1 |
| Belemezova, M | 1 |
| Milenska, T | 1 |
| Kirov, G | 1 |
5 other studies available for flumazenil and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
Changes in hippocampal GABAA receptor subunit composition in bipolar 1 disorder.
Topics: Adult; Aged; Binding, Competitive; Bipolar Disorder; Brain Chemistry; Clonazepam; Female; Flumazenil | 2005 |
A change in the density of [(3)H]flumazenil, but not [(3)H]muscimol binding, in Brodmann's Area 9 from subjects with bipolar disorder.
Topics: Adult; Aged; Autoradiography; Bipolar Disorder; Brain Mapping; Female; Flumazenil; Frontal Lobe; Hum | 2001 |
Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.
Topics: Bipolar Disorder; Bulgaria; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 4; Chromosomes, Hum | 2005 |
Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.
Topics: Adolescent; Adult; Aged; Alleles; Bipolar Disorder; Bulgaria; Female; Founder Effect; Genetic Hetero | 2009 |
A linkage study of affective disorders in two Bulgarian Gypsy families: results for candidate regions on chromosomes 18 and 21.
Topics: Bipolar Disorder; Bulgaria; Centromere; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 21; Fe | 1998 |