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flumazenil and Acute Kidney Injury

flumazenil has been researched along with Acute Kidney Injury in 3 studies

Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Renal hypouricemia (RHUC) is a heterogeneous inherited disorder characterized by impaired tubular uric acid (UA) transport with severe complications, such as acute kidney injury (AKI)."3.79Novel allelic variants and evidence for a prevalent mutation in URAT1 causing renal hypouricemia: biochemical, genetics and functional analysis. ( Hulkova, H; Ichida, K; Jahnova, H; Krylov, V; Kryspinova, L; Nakamura, M; Sebesta, I; Stiburkova, B, 2013)
"To report a fatal case of refractory status epilepticus precipitated by flumazenil use in a mixed benzodiazepine-tricyclic antidepressant overdose."3.69Fatal seizures after flumazenil administration in a patient with mixed overdose. ( DiSalvo, RP; Haverkos, GP; Imhoff, TE, 1994)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Haverkos, GP1
DiSalvo, RP1
Imhoff, TE1
Williams, D1
Dawson, P1
Stiburkova, B1
Sebesta, I1
Ichida, K1
Nakamura, M1
Hulkova, H1
Krylov, V1
Kryspinova, L1
Jahnova, H1

Other Studies

3 other studies available for flumazenil and Acute Kidney Injury

ArticleYear
Fatal seizures after flumazenil administration in a patient with mixed overdose.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:12

    Topics: Acute Kidney Injury; Adult; Antidepressive Agents, Tricyclic; Benzodiazepines; Charcoal; Drug Overdo

1994
An unusual result with flumazenil.
    Anaesthesia and intensive care, 1989, Volume: 17, Issue:3

    Topics: Acute Kidney Injury; Critical Care; Female; Flumazenil; Humans; Midazolam; Middle Aged; Nervous Syst

1989
Novel allelic variants and evidence for a prevalent mutation in URAT1 causing renal hypouricemia: biochemical, genetics and functional analysis.
    European journal of human genetics : EJHG, 2013, Volume: 21, Issue:10

    Topics: Absorption; Acute Kidney Injury; Adult; Alleles; Animals; Child; Czech Republic; Endoplasmic Reticul

2013