flumazenil has been researched along with Acute Brain Injuries in 13 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Traumatic brain injuries demonstrate various symptoms, including the disturbance of higher brain function, which is not visualized as a morphological lesion on magnetic resonance (MR) imaging." | 1.39 | Evaluation of cerebral function using iomazenil SPECT for patients with traumatic brain injury. ( Endo, K; Shibata, Y, 2013) |
| "Four patients with homonymous hemianopia and 15 healthy subjects were examined using PET to measure cerebral glucose metabolism, C-flumazenil (FMZ) binding to the central benzodiazepine receptor, and MPDX binding to A1R." | 1.38 | Increased adenosine A1 receptor levels in hemianopia patients after cerebral injury: an application of PET using 11C-8-dicyclopropylmethyl-1-methyl-3-propylxanthine. ( Ishii, K; Ishiwata, K; Kimura, Y; Kiyosawa, M; Mochizuki, M; Nariai, T; Oda, K; Suzuki, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Sebastiani, A | 1 |
| Bender, S | 1 |
| Schäfer, MKE | 1 |
| Thal, SC | 1 |
| Koizumi, H | 2 |
| Fujisawa, H | 2 |
| Suehiro, E | 2 |
| Iwanaga, H | 2 |
| Nakagawara, J | 3 |
| Suzuki, M | 2 |
| Kamiyama, K | 1 |
| Takahashi, M | 1 |
| Nakamura, H | 1 |
| Shibata, Y | 1 |
| Endo, K | 1 |
| Qin, P | 1 |
| Wu, X | 2 |
| Duncan, NW | 1 |
| Bao, W | 1 |
| Tang, W | 1 |
| Zhang, Z | 1 |
| Hu, J | 1 |
| Jin, Y | 1 |
| Gao, L | 1 |
| Lu, L | 1 |
| Guan, Y | 1 |
| Lane, T | 1 |
| Huang, Z | 1 |
| Bodien, YG | 1 |
| Giacino, JT | 1 |
| Mao, Y | 1 |
| Northoff, G | 1 |
| Ochalski, PG | 2 |
| Okonkwo, DO | 2 |
| Bell, MJ | 1 |
| Adelson, PD | 2 |
| Fellows-Mayle, W | 1 |
| Hsieh, LB | 1 |
| Srinivas, R | 1 |
| Dixon, CE | 1 |
| Kurokawa, T | 1 |
| Heiss, WD | 1 |
| Kawai, N | 1 |
| Maeda, Y | 1 |
| Kudomi, N | 1 |
| Yamamoto, Y | 1 |
| Nishiyama, Y | 1 |
| Tamiya, T | 1 |
| Suzuki, Y | 1 |
| Nariai, T | 1 |
| Kiyosawa, M | 1 |
| Mochizuki, M | 1 |
| Kimura, Y | 1 |
| Oda, K | 1 |
| Ishii, K | 1 |
| Ishiwata, K | 1 |
| Buylaert, WA | 1 |
| Sihver, S | 1 |
| Marklund, N | 1 |
| Hillered, L | 1 |
| Långström, B | 1 |
| Watanabe, Y | 1 |
| Bergström, M | 1 |
1 review available for flumazenil and Acute Brain Injuries
| Article | Year |
|---|---|
Coma induced by intoxication.
Topics: Accidental Falls; Alcohol-Induced Disorders, Nervous System; Alcoholic Intoxication; Antidotes; Brai | 2000 |
12 other studies available for flumazenil and Acute Brain Injuries
| Article | Year |
|---|---|
Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury.
Topics: Animals; Benzodiazepines; Brain; Brain Injuries; Brain Injuries, Traumatic; Flumazenil; Humans; Mice | 2022 |
Cortical damage following traumatic brain injury evaluated by iomazenil SPECT and in vivo microdialysis.
Topics: Brain Injuries; Cerebral Cortex; Female; Flumazenil; Humans; Middle Aged; Time Factors; Tomography, | 2013 |
Cortical neuron loss in post-traumatic higher brain dysfunction using (123)I-iomazenil SPECT.
Topics: Adult; Aged; Brain; Brain Injuries; Brain Mapping; Cell Death; Female; Flumazenil; Humans; Male; Mid | 2013 |
Evaluation of cerebral function using iomazenil SPECT for patients with traumatic brain injury.
Topics: Adolescent; Aged; Brain Injuries; Brain Mapping; Flumazenil; Humans; Magnetic Resonance Imaging; Mal | 2013 |
GABAA receptor deficits predict recovery in patients with disorders of consciousness: A preliminary multimodal [(11) C]Flumazenil PET and fMRI study.
Topics: Adult; Behavior; Brain Injuries; Consciousness Disorders; Female; Flumazenil; Gyrus Cinguli; Humans; | 2015 |
Reversal of sedation with flumazenil in a child after traumatic brain injury.
Topics: Accidents, Traffic; Benzodiazepines; Brain Injuries; Child; Female; Flumazenil; Humans; Hypnotics an | 2009 |
Flumazenil administration attenuates cognitive impairment in immature rats after controlled cortical impact.
Topics: Animals; Brain; Brain Chemistry; Brain Injuries; Cognition Disorders; Disease Models, Animal; Dose-R | 2010 |
Recovered neuronal viability revealed by Iodine-123-iomazenil SPECT following traumatic brain injury.
Topics: Adult; Aged; Brain; Brain Injuries; Cell Survival; Female; Flumazenil; Humans; Iodine Radioisotopes; | 2010 |
Reversible dysfunction of receptors in traumatic brain injury?
Topics: Brain Injuries; Flumazenil; Humans; Iodine Radioisotopes; Neurons; Receptors, GABA-A | 2010 |
Focal neuronal damage in patients with neuropsychological impairment after diffuse traumatic brain injury: evaluation using ¹¹C-flumazenil positron emission tomography with statistical image analysis.
Topics: Adult; Brain; Brain Injuries; Brain Mapping; Carbon Isotopes; Cognition; Cognition Disorders; Female | 2010 |
Increased adenosine A1 receptor levels in hemianopia patients after cerebral injury: an application of PET using 11C-8-dicyclopropylmethyl-1-methyl-3-propylxanthine.
Topics: Adult; Aged; Brain Injuries; Female; Flumazenil; Glucose; Hemianopsia; Humans; Male; Middle Aged; Po | 2012 |
Changes in mACh, NMDA and GABA(A) receptor binding after lateral fluid-percussion injury: in vitro autoradiography of rat brain frozen sections.
Topics: Animals; Autoradiography; Binding Sites; Brain; Brain Injuries; Cerebral Cortex; Dizocilpine Maleate | 2001 |