flumazenil has been researched along with ALS - Amyotrophic Lateral Sclerosis in 6 studies
Flumazenil: A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
flumazenil : An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We used the benzodiazepine GABA(A) marker [(11)C] flumazenil to study cerebral dysfunction in amyotrophic lateral sclerosis (ALS) with PET." | 3.70 | Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil. ( Al-Chalabi, A; Brooks, DJ; Leigh, PN; Lloyd, CM; Richardson, MP, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caioli, S | 1 |
| Pieri, M | 1 |
| Antonini, A | 1 |
| Guglielmotti, A | 1 |
| Severini, C | 1 |
| Zona, C | 1 |
| Turner, MR | 3 |
| Hammers, A | 3 |
| Al-Chalabi, A | 3 |
| Shaw, CE | 2 |
| Andersen, PM | 2 |
| Brooks, DJ | 4 |
| Leigh, PN | 4 |
| Osei-Lah, AD | 1 |
| Mills, KR | 1 |
| Wicks, P | 1 |
| Abrahams, S | 1 |
| Goldstein, LH | 1 |
| Gredal, O | 1 |
| Pakkenberg, B | 1 |
| Nielsen, M | 1 |
| Lloyd, CM | 1 |
| Richardson, MP | 1 |
6 other studies available for flumazenil and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Monocyte Chemoattractant Protein-1 upregulates GABA-induced current: evidence of modified GABAA subunit composition in cortical neurons from the G93A mouse model of Amyotrophic Lateral Sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Cerebral Cortex; Chemokine CCL2; Disease Mo | 2013 |
Distinct cerebral lesions in sporadic and 'D90A' SOD1 ALS: studies with [11C]flumazenil PET.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Carbon Radioisotopes; Cerebral Cortex; Disease Progressi | 2005 |
Abnormal cortical excitability in sporadic but not homozygous D90A SOD1 ALS.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Case-Control Studies; Cerebral Cortex; Disease Progressi | 2005 |
Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Carbon Radioisotopes; Cognition Disorders; Female; Fluma | 2008 |
Muscarinic, N-methyl-D-aspartate (NMDA) and benzodiazepine receptor binding sites in cortical membranes from amyotrophic lateral sclerosis patients.
Topics: Aged; Amyotrophic Lateral Sclerosis; Binding Sites; Brain Chemistry; Dizocilpine Maleate; Excitatory | 1996 |
Extramotor involvement in ALS: PET studies with the GABA(A) ligand [(11)C]flumazenil.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Benzodiazepines; Brain Mapping; Carbon Radioisotopes; Ce | 2000 |