Page last updated: 2024-10-27

flufenamic acid and Insulinoma

flufenamic acid has been researched along with Insulinoma in 1 studies

Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
" Here, we demonstrate, using patch clamp electrophysiology, that the non-steroidal anti-inflammatory compound flufenamic acid (FFA) inhibits recombinant human TRPM2 (hTRPM2) as well as currents activated by intracellular ADP-ribose in the CRI-G1 rat insulinoma cell line."3.72Flufenamic acid is a pH-dependent antagonist of TRPM2 channels. ( Benham, CD; Hill, K; McNulty, S; Randall, AD, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hill, K1
Benham, CD1
McNulty, S1
Randall, AD1

Other Studies

1 other study available for flufenamic acid and Insulinoma

ArticleYear
Flufenamic acid is a pH-dependent antagonist of TRPM2 channels.
    Neuropharmacology, 2004, Volume: 47, Issue:3

    Topics: Adenosine Diphosphate Ribose; Animals; Cell Line; Dose-Response Relationship, Drug; Drug Interaction

2004