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flufenamic acid and Innate Inflammatory Response

flufenamic acid has been researched along with Innate Inflammatory Response in 31 studies

Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.

Research Excerpts

ExcerptRelevanceReference
" Flufenamic acid and mefenamic acid are efficacious in NLRP3-dependent rodent models of inflammation in air pouch and peritoneum."3.83Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models. ( Allan, SM; Bagnall, J; Baldwin, AG; Booth, SJ; Brough, D; Daniels, MJ; Eder, C; Fasolino, V; Fischer, N; Freeman, S; Galea, J; Harte, MK; Jackson, J; Koziel, V; Latta, C; Lawrence, CB; Paszek, P; Pillot, T; Rivers-Auty, J; Schilling, T; Spencer, NG; Watremez, W; White, CS; Wong, R; Yu, S, 2016)
"Burns are soft tissue injuries that require particular care for wound healing."1.51Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications. ( Albu-Kaya, MG; Costache, M; Danilă, E; Dinescu, S; Ghica, MV; Ignat, SR; Lazar, AD; Marin, MM; Marin, Ș; Udeanu, DI, 2019)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199024 (77.42)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (22.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Maccari, R1
Ottanà, R1
Vivier, D1
Bennis, K1
Lesage, F1
Ducki, S1
Spray, DC1
Iglesias, R1
Shraer, N1
Suadicani, SO1
Belzer, V1
Hanstein, R1
Hanani, M1
Dinescu, S1
Ignat, SR1
Lazar, AD1
Marin, Ș1
Danilă, E1
Marin, MM1
Udeanu, DI1
Ghica, MV1
Albu-Kaya, MG1
Costache, M1
Calder, BW1
Matthew Rhett, J1
Bainbridge, H1
Fann, SA1
Gourdie, RG1
Yost, MJ1
Daniels, MJ1
Rivers-Auty, J1
Schilling, T1
Spencer, NG1
Watremez, W1
Fasolino, V1
Booth, SJ1
White, CS1
Baldwin, AG1
Freeman, S1
Wong, R1
Latta, C1
Yu, S1
Jackson, J1
Fischer, N1
Koziel, V1
Pillot, T1
Bagnall, J1
Allan, SM1
Paszek, P1
Galea, J1
Harte, MK1
Eder, C1
Lawrence, CB1
Brough, D1
WINDER, CV2
WAX, J2
SERRANO, B1
JONES, EM1
McPHEE, ML1
WELFORD, M1
Mörsdorf, K2
Cornelissen, G1
Balestrieri, B1
Capasso, L1
Masiello, S1
Castaldo, S1
Capasso, F1
Caramanis, C1
Varonos, DD1
Dell, HD1
Fiedler, J1
Jacobi, H1
Kolle, J1
Roubal, Z1
Grimová, J1
Nĕmecek, O1
Cepelák, V1
Ito, M2
Anspach, K1
Perper, RJ1
Sanda, M1
Chinea, G1
Oronsky, AL1
Jancsó-Gábor, A1
Szolcsányi, J1
Mizushima, Y1
Tsukada, W1
Akimoto, T1
Iizuka, Y1
Tanaka, K1
Bacon, PA1
Dieppe, PA1
Wawrzyńska-Pagowska, J1
Di Perri, T1
Auteri, A1
Tsurumi, K2
Hiramatsu, Y2
Nozaki, M1
Hayashi, M2
Shibuya, T2
Yamaguchi, A1
Kimura, S1
Kaump, DH1
Nakanishi, M1
Imamura, H1
Ikegami, K1
Goto, K1
Homma, M1
Jahn, U1
Adrian, RW1

Reviews

3 reviews available for flufenamic acid and Innate Inflammatory Response

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc

2016
[Clinical use of non-steroid anti-inflammatory agents].
    Reumatologia, 1974, Volume: 12, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Aspirin; Cell Mi

1974
[Non-steroidal anti-inflammatory drugs for eye diseases].
    Ganka. Ophthalmology, 1968, Volume: 10, Issue:12

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Enzyme Therapy; Eye Diseases;

1968

Trials

1 trial available for flufenamic acid and Innate Inflammatory Response

ArticleYear
Skin testing in the assessment of antiinflammatory drugs in man.
    The Journal of clinical pharmacology and new drugs, 1972, Volume: 12, Issue:7

    Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Flufenamic Acid; Histamine; Humans; Hypersensiti

1972

Other Studies

27 other studies available for flufenamic acid and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Targeting aldose reductase for the treatment of diabetes complications and inflammatory diseases: new insights and future directions.
    Journal of medicinal chemistry, 2015, Mar-12, Volume: 58, Issue:5

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Diabetes Complications; Diabetes Mellitus; Enzyme Inhibito

2015
Gap junction mediated signaling between satellite glia and neurons in trigeminal ganglia.
    Glia, 2019, Volume: 67, Issue:5

    Topics: Animals; Boron Compounds; Carbenoxolone; Cells, Cultured; Disease Models, Animal; Female; Flufenamic

2019
Efficiency of Multiparticulate Delivery Systems Loaded with Flufenamic Acid Designed for Burn Wound Healing Applications.
    Journal of immunology research, 2019, Volume: 2019

    Topics: Animals; Burns; Capsules; Cell Proliferation; Cell Survival; Cells, Cultured; Collagen; Drug Compoun

2019
Inhibition of connexin 43 hemichannel-mediated ATP release attenuates early inflammation during the foreign body response.
    Tissue engineering. Part A, 2015, Volume: 21, Issue:11-12

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Biotinylation; Calcium; Cells, Cultured; Conne

2015
Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models.
    Nature communications, 2016, 08-11, Volume: 7

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Cell Death;

2016
Anti-inflammatory and antipyretic properties of N-(alpha,alpha,alpha-trifluoro-m-tolyl) anthranilic acid (CI-440; flufenamic acid).
    Arthritis and rheumatism, 1963, Volume: 6

    Topics: Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Body Temperature; Eryt

1963
ANTI-INFLAMMATORY AND ANTIPYRETIC PROPERTIES OF N-(2,6-DICHLORO-M-TOLYL)ANTHRANILIC ACID (CI-583).
    The Journal of pharmacology and experimental therapeutics, 1965, Volume: 148

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Antipyretics; Aspirin;

1965
[Contribution to the evaluation of anti-inflammatory agents in vitro].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 15, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cortisone; Esterases; Flufenamic Acid; Indomethacin; Inflammation

1966
[Scopolamine and its pharmacological effects on some experimental inflammation tests].
    La Clinica terapeutica, 1980, Jan-31, Volume: 92, Issue:2

    Topics: Animals; Carrageenan; Cellulose; Dextrans; Edema; Flufenamic Acid; Granuloma; Indomethacin; Inflamma

1980
The influence of acetylsalicylic acid, phenylbutazone, indomethacin, and flufenamic acid on the kinetics of leucocytes during acute inflammation.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 4

    Topics: Analgesics; Animals; Aspirin; Cell Movement; Flufenamic Acid; Indomethacin; Inflammation; Kinetics;

1980
[Gas-liquid chromatographic determination of etofenamate/ Determination, method and use in biological material (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Flufenamic Acid; Half-Life; H

1981
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
    Acta Universitatis Carolinae. Medica. Monographia, 1972, Volume: 53

    Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depressio

1972
[Influence of various drugs on the tissue permeability. 6. Effect of anti-inflammatory drugs on quantitative changes in connective tissue components in inflamed tissues of filter paper-implanted rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Barbiturates; Benzyl Compounds; Connective

1973
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D

1971
Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation.
    The Journal of laboratory and clinical medicine, 1974, Volume: 84, Issue:3

    Topics: Animals; Bucladesine; Carrageenan; Chemotaxis; Chloroquine; Chlorpromazine; Chromium Radioisotopes;

1974
Action of rare earth metal complexes on neurogenic as well as on bradykinin-induced inflammation.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antivenins; Blood Coagulation; Bradykinin; Catech

1970
A modification of rat adjuvant arthritis for testing antirheumatic drugs.
    The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:10

    Topics: Adjuvants, Immunologic; Aminopyrine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthr

1972
][A new method for screening of analgesics applied to heat induced inflammatory pain].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:5

    Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Hab

1974
[Influence of various drugs on the tissue permeability. 7. Effect of anti-inflammatory drugs on the changes in mucopolysaccharase activity in inflamed tissues of filter paper-implanted rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Dexamethasone; Enzyme Activation; Female; F

1973
[Anti-complement activity in vitro and in vivo of some non-steroid anti-inflammatory drugs].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Feb-28, Volume: 49, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Complement Inactivator Proteins; Flufenamic Acid; Hemoly

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 2. On subacute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Body Weight; Ed

1973
Experimental observations on flufenamic, mefanamic and meclofenamic acids. II. Toxicology in animals.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Aluminum; Animals; Anti-Inflammatory Agents; Calcium; Colon; Dogs; Edema; Female; Flufenamic Acid; F

1966
Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Acid Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Antibody Formation; Aspirin; Blood

1970
[Clinical evaluation of non-steroid anti-inflammatory drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Flufenamic Acid; Humans; Indomethacin; Inf

1968
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo

1969