flufenamic acid has been researched along with Hemolysis in 21 studies
Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The kinetic studies in isotonic suspensions of erythrocytes indicated that the hemolysis induced by the amphipathic drug chlorpromazine (CPZ) or flufenamic acid (FA) was retarded by addition of sugars, and the degree of the anti-hemolytic effect increased with increases in molecular size." | 3.69 | Protective effects of neutral amino acids against amphipathic drug-induced hemolysis. ( Iida, T; Kado, Y; Morimoto, Y; Shiota, M; Takeuchi, Y; Yutani, Y, 1995) |
| "beta-Cyclodextrin (beta-CyD) significantly protected the human erythrocytes from hemolysis and shape changes induced with chlorpromazine and flufenamic acid in isotonic solution." | 3.66 | Protective effects of cyclodextrins on drug-induced hemolysis in vitro. ( Irie, T; Otagiri, M; Sunada, M; Tsubaki, K; Uekama, K, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gullikson, GW | 1 |
| Sender, M | 1 |
| Bass, P | 1 |
| Uekama, K | 1 |
| Irie, T | 1 |
| Sunada, M | 1 |
| Otagiri, M | 1 |
| Tsubaki, K | 1 |
| Raghava, GP | 1 |
| Goel, A | 1 |
| Singh, AM | 1 |
| Varshney, GC | 1 |
| Morimoto, Y | 1 |
| Yutani, Y | 1 |
| Kado, Y | 1 |
| Iida, T | 1 |
| Shiota, M | 1 |
| Takeuchi, Y | 1 |
| Roubal, Z | 1 |
| Grimová, J | 1 |
| Nĕmecek, O | 1 |
| Cepelák, V | 1 |
| Tanaka, K | 1 |
| Kobayashi, K | 1 |
| Kazui, S | 1 |
| Harrity, TW | 1 |
| Goldlust, MB | 1 |
| Mizushima, Y | 2 |
| Sakai, S | 2 |
| Tsurumi, K | 3 |
| Nozaki, M | 2 |
| Hayashi, M | 3 |
| Yamaguchi, A | 1 |
| Hiramatsu, Y | 2 |
| Di Perri, T | 1 |
| Auteri, A | 1 |
| Fujimura, H | 1 |
| Abe, A | 1 |
| Nakano, K | 1 |
| Shibuya, T | 1 |
| Fujihira, E | 3 |
| Otomo, S | 3 |
| Sota, K | 1 |
| Nakazawa, M | 1 |
| Kalbhen, DA | 1 |
| Gelderblom, P | 1 |
| Domenjoz, R | 1 |
| Nakanishi, M | 2 |
| Imamura, H | 2 |
| Goto, K | 2 |
| Yamaura, M | 1 |
| Ikegami, K | 1 |
| Artini, D | 1 |
| Logemann, W | 1 |
| Melloni, P | 1 |
| Vita, G | 1 |
| Buttinoni, A | 1 |
| Tommasini, R | 1 |
| Brown, JH | 1 |
| Mackey, HK | 1 |
21 other studies available for flufenamic acid and Hemolysis
| Article | Year |
|---|---|
Laxative-like effects of nonsteroidal anti-inflammatory drugs on intestinal fluid movement and membrane integrity.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Cathartics; Cricetinae; Diarrh | 1982 |
Protective effects of cyclodextrins on drug-induced hemolysis in vitro.
Topics: Chlorpromazine; Cyclodextrins; Dextrins; Erythrocytes; Flufenamic Acid; Hemolysis; Humans; In Vitro | 1981 |
A simple microassay for computing the hemolytic potency of drugs.
Topics: Animals; Electronic Data Processing; Erythrocytes; Flufenamic Acid; Hemolysis; Ibuprofen; Indomethac | 1994 |
Protective effects of neutral amino acids against amphipathic drug-induced hemolysis.
Topics: Amino Acids; Animals; Carbohydrates; Chlorpromazine; Erythrocytes; Flufenamic Acid; Hemolysis; In Vi | 1995 |
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depressio | 1972 |
Temperature-dependent reaction of flufenamic acid with rat erythrocyte membrane.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents; Cell Membrane; Chlorpromazine; Dose-Response | 1973 |
Anti-complement effects of two anti-inflammatory agents. Niflumic and flufenamic acids.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Antibodies; Buffers; Calcium; Chelating Agents | 1974 |
Stabilization of erythrocyte membrane by non-steroianti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Cell Membrane; Dogs; Erythrocytes; Flufenamic Acid; Hemolysis; Ho | 1969 |
[Pharmacological studies on niflumic acid, with special reference to the comparison with fenametes. 1. Anti-inflammatory and analgesic actions].
Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability; | 1972 |
[Anti-complement activity in vitro and in vivo of some non-steroid anti-inflammatory drugs].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Complement Inactivator Proteins; Flufenamic Acid; Hemoly | 1973 |
[Pharmacological studies of N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F1). 3. Interaction with proteins].
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Benzyl Compounds; Blo | 1973 |
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth | 1973 |
[Anti-inflammatory activities of compounds related to anthranilic acid. II. On acridine mono- and dicarboxylic, and oxo-acridan monocarboxylic acid derivatives].
Topics: Acridines; Aminopyrine; Animals; Anti-Inflammatory Agents; Carboxylic Acids; Carrageenan; Cattle; Ch | 1971 |
Effects of antirheumatic drugs on human erythrocyte membranes.
Topics: Aminobenzoates; Analgesics; Antipyrine; Aspirin; Barbiturates; Benzoates; Cell Membrane; Erythrocyte | 1970 |
[Studies on anti-inflammatory agents. IX. Effect of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine(Y-3642) on heat-induced hemolysis].
Topics: Animals; Anti-Inflammatory Agents; Carbon Isotopes; Erythrocytes; Flufenamic Acid; Hemolysis; In Vit | 1970 |
[Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. II. On UV-induced canine erythrocyte hemolysisand lipid peroxidation, on UV-induced peroxide formation in extracted lipid, and on irradiated lipid-induced hemolysis].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Capillary Permeability; Chloroquine; Dogs | 1970 |
[Stabilizing effect of anti-inflammatory drugs on erythrocyte membrane. I. On hemolysis and lipid peroxidation induced by H202 in canine erythrocyte].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Cell Membrane; Chloroquine; Dogs; Erythro | 1970 |
Mode of stabilizing action of non-steroid anti-inflammatory drugs on erythrocyte membrane.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Blood Coagulation; Cell Membrane; Dogs; Ery | 1970 |
Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine.
Topics: Acid Phosphatase; Analgesics; Animals; Anti-Inflammatory Agents; Antibody Formation; Aspirin; Blood | 1970 |
[Analgesic and antiphlogistic action of amide and amine compounds. 1].
Topics: Amides; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Depression, Chemical; Ed | 1970 |
Further studies on the erythrocyte anti-inflammatory assay.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Aspirin; Dimethyl Sulfoxide; Erythrocytes; Estrog | 1968 |