flufenamic acid has been researched along with Diarrhea in 8 studies
Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Flufenamic acid (FFA) has previously been demonstrated to be a potent activator of AMP-activated protein kinase (AMPK), which is a negative regulator of NF-κB signaling." | 5.46 | Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation. ( Chatsudthipong, V; Chittavanich, P; Kittayaruksakul, S; Muanprasat, C; Pongkorpsakol, P; Satitsri, S; Srimanote, P; Wongkrasant, P, 2017) |
| "Flufenamic acid (FFA) has previously been demonstrated to be a potent activator of AMP-activated protein kinase (AMPK), which is a negative regulator of NF-κB signaling." | 1.46 | Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation. ( Chatsudthipong, V; Chittavanich, P; Kittayaruksakul, S; Muanprasat, C; Pongkorpsakol, P; Satitsri, S; Srimanote, P; Wongkrasant, P, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pongkorpsakol, P | 1 |
| Satitsri, S | 1 |
| Wongkrasant, P | 1 |
| Chittavanich, P | 1 |
| Kittayaruksakul, S | 1 |
| Srimanote, P | 1 |
| Chatsudthipong, V | 1 |
| Muanprasat, C | 1 |
| Gullikson, GW | 1 |
| Sender, M | 1 |
| Bass, P | 1 |
| Zwarenstein, H | 1 |
| Sapeika, N | 1 |
| Holmes, JH | 1 |
| Bain, LS | 1 |
| Masheter, HC | 2 |
| Holmes, EL | 1 |
| Hill, AG | 1 |
| Cardoe, N | 1 |
| Simpson, MR | 1 |
| Simpson, NR | 1 |
1 review available for flufenamic acid and Diarrhea
| Article | Year |
|---|---|
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
4 trials available for flufenamic acid and Diarrhea
| Article | Year |
|---|---|
Flufenamic acid and indomethacin in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diarrhea; Digestion; Fema | 1966 |
Experimental observations on flufenamic, mefenamic, and meclofenamic acids. IV. Toleration by normal human subjects.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Biphenyl Compounds; Blood Coagulation; Blood Urea Nitrogen | 1966 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
A clinical trial of flufenamic acid in the treatment of rheumatoid arthritis.
Topics: Abdomen, Acute; Acetaminophen; Aluminum; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate | 1966 |
4 other studies available for flufenamic acid and Diarrhea
| Article | Year |
|---|---|
Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation.
Topics: AMP-Activated Protein Kinases; Animals; Body Fluids; Calcium-Calmodulin-Dependent Protein Kinase Kin | 2017 |
Laxative-like effects of nonsteroidal anti-inflammatory drugs on intestinal fluid movement and membrane integrity.
Topics: Alprostadil; Animals; Anti-Inflammatory Agents; Aspirin; Body Fluids; Cathartics; Cricetinae; Diarrh | 1982 |
Effect of anti-inflammatory drugs on lipase in vitro.
Topics: Animals; Anti-Inflammatory Agents; Diarrhea; Flufenamic Acid; Humans; In Vitro Techniques; Lipase; M | 1976 |
New drugs. 8. Flufenamic acid in rheumatoid arthritis. Comparison with aspirin and the results of extended treatment.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Diarrhea; Flufenamic | 1966 |