flufenamic acid has been researched along with Arthritis, Rheumatoid in 56 studies
Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The absorption of etofenamate (CAS 30544-47-9, Rheumon gel) by iontophoresis in 11 patients with low back pain and in 13 patients with synovitis of the knee was evaluated." | 5.09 | Etofenamate levels in human serum and synovial fluid following iontophoresis. ( Bálint, G; Bariska, J; Bender, T; Rojkovich, B, 2001) |
| " Levels of PGB (presumed to arise from PGE) in synovial fluids are elevated in the majority of a group of patients with inflammatory rheumatic diseases, as compared to similar patients treated with aspirin and indomethacin and patients with osteoarthritis." | 3.65 | Prostaglandins in the rheumatic diseases. ( Levine, L; McGuire, MB; Robinson, DR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (98.21) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (1.79) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| COODLEY, EL | 1 |
| Simpson, MR | 2 |
| Simpson, NR | 2 |
| Masheter, HC | 4 |
| Hardy, SM | 1 |
| Sydnes, OA | 2 |
| Mason, RM | 1 |
| Barnardo, DE | 1 |
| Fox, WR | 1 |
| Weatherall, M | 2 |
| Tsvetkova, ES | 1 |
| Sigidin, IaA | 1 |
| Kagan, G | 1 |
| Huddlestone, L | 1 |
| Wolstencroft, P | 1 |
| Bender, T | 1 |
| Bariska, J | 1 |
| Rojkovich, B | 1 |
| Bálint, G | 1 |
| Heindl, I | 1 |
| Lorenz, D | 1 |
| Sieberns, S | 1 |
| Blumberger, W | 1 |
| Robinson, DR | 1 |
| McGuire, MB | 1 |
| Levine, L | 1 |
| Leynadier, F | 1 |
| Perrault, M | 1 |
| Mavrikakis, ME | 1 |
| Madkour, MM | 1 |
| Buchanan, WW | 2 |
| Reinicke, C | 1 |
| Shichikawa, K | 1 |
| Onoda, T | 1 |
| Klein, G | 1 |
| Wottawa, A | 1 |
| Wax, J | 1 |
| Tessman, DK | 1 |
| Winder, CV | 1 |
| Stephens, MD | 1 |
| Cherevatov, BG | 1 |
| Shelest, AN | 1 |
| Volnenko, NB | 1 |
| Cherevatova, SKh | 1 |
| Kluft, C | 1 |
| Cooper, P | 1 |
| Jie, AF | 1 |
| Lowe, GD | 1 |
| Forbes, CD | 1 |
| Blamey, SL | 1 |
| van de Putte, LB | 1 |
| Mastandrea, G | 1 |
| Migliari, M | 1 |
| De Salcedo, I | 1 |
| Fonseca Ferreira, FM | 1 |
| Silva, JL | 1 |
| Carrington, MD | 1 |
| Mizushima, Y | 1 |
| Cosh, JA | 1 |
| Siegmeth, W | 1 |
| Herkner, W | 1 |
| Tausch, G | 1 |
| Tuschl, P | 1 |
| Dunky, A | 1 |
| Eberl, R | 1 |
| Fujimura, H | 1 |
| Tsurumi, K | 1 |
| Go, K | 1 |
| Hiramatsu, Y | 1 |
| Tamura, Y | 1 |
| Evans, DP | 1 |
| Lees, LJ | 1 |
| Wawrzyńska-Pagowska, J | 1 |
| Mathies, H | 3 |
| Kanková, D | 1 |
| Vojtísek, O | 1 |
| Pavelka, K | 1 |
| Hándlová, D | 1 |
| Jeremy, R | 1 |
| Eichhorn, M | 1 |
| Bain, LS | 1 |
| Fearnley, ME | 2 |
| Hill, AG | 2 |
| Cardoe, N | 1 |
| Beltrán Gutiérrez, J | 1 |
| Fernández del Vallado, P | 1 |
| Gijón Baños, J | 1 |
| Dick, WC | 1 |
| Schmied, P | 1 |
| Van Rossum, P | 1 |
| Fallet, GH | 1 |
| Bossa, G | 1 |
| Giordano, M | 1 |
| Camus, JP | 1 |
| Tudhope, GR | 1 |
| Cabanel, G | 1 |
| Phélip, X | 1 |
| Verdier, JM | 1 |
| Rajan, KT | 1 |
| Barr, A | 1 |
| Whitwell, E | 1 |
| Böni, A | 1 |
| López Prats, JL | 1 |
| Hingorani, K | 1 |
| Kater, RM | 1 |
| Brown, JH | 1 |
| Mackey, HK | 1 |
| Gigante, D | 1 |
| Teodori, S | 1 |
| Homma, M | 1 |
6 reviews available for flufenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
[Nonsteroid antirheumatic agents].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Flufenamic Acid; Humans; Indomethacin; | 1977 |
[Clinical use of non-steroid anti-inflammatory agents].
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Aspirin; Cell Mi | 1974 |
A critical appraisal of therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Arthritis, Rheumatoid; Aspirin; Flufenamic | 1968 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
Advances in the treatment of rheumatic disorders.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Female; Flu | 1971 |
[The conservative treatment of chronic inflammatory rheumatism].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Anti-Inflammatory Agents; Antimalarials; Art | 1969 |
19 trials available for flufenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Controlled clinical trial of flufenamic acid in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Flufenamic Acid; Humans; Indomethaci | 1967 |
[Comparative effectiveness of new antirheumatic drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Flufenamic Ac | 1980 |
Flufenamic acid and placebo compared in rheumatoid arthritis and osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Fl | 1981 |
Etofenamate levels in human serum and synovial fluid following iontophoresis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chromatography, High Press | 2001 |
[Clinical trial of the new percutaneously active antirheumatic etofenamate. Summarising report (author's transl)].
Topics: Administration, Topical; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Back Pain; Bursitis; Clinic | 1977 |
[Effect of niflumic acid on chronic rheumatoid arthritis].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Female; Flufena | 1976 |
[Experiences with a new combination drug (Realin) in the treatment of acute rheumatic conditions].
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Combinations; Drug | 1974 |
Trial design for assessing initiation of anti-inflammatory therapy.
Topics: Adult; Analgesics; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Dose-Respon | 1972 |
[Evaluation of the therapeutic action of flufenamic acid in patients with chronic polyarthritis in a double blind study].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Flufenamic Acid; Humans; | 1967 |
Flufenamic acid and indomethacin in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diarrhea; Digestion; Fema | 1966 |
An investigation of possible synergism between flufenamic acid and prednisone.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Synergism; Flufenami | 1966 |
Clinical trials of the fenamates. The value of computers in analysing clinical trials.
Topics: Analysis of Variance; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Com | 1966 |
Review of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diarrhea; Dyspep | 1966 |
A controlled clinical trial of flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Flufenamic Acid; | 1966 |
A clinical trial of flufenamic acid in the treatment of rheumatoid arthritis.
Topics: Abdomen, Acute; Acetaminophen; Aluminum; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate | 1966 |
[Double-blind study using flufenamic acid (F.I. 440) and oxyphenylbutazone in rheumatoid arthritis and ankylosing spine].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Flufenamic Acid; Fluorine | 1968 |
Flufenamic acid in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Clinical Trials as To | 1967 |
Double-blind crossover trial comparing ibuprofen with flufenamic acid in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Benzyl Compounds; Female; Flufenamic A | 1970 |
Double-blind evaluation of the analgesic and toxic effects of flufenamic acid and mefenamic acid in patients with chronic pain.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; | 1968 |
32 other studies available for flufenamic acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Evaluation of drug therapy in rheumatoid arthritis-study of flufenamic acid.
Topics: Arthritis; Arthritis, Rheumatoid; Flufenamic Acid; Humans; ortho-Aminobenzoates | 1963 |
Flufenamic acid in rheumatoid arthritis. The second six months of treatment.
Topics: Alanine Transaminase; Alcohol Oxidoreductases; Alkaline Phosphatase; Anti-Inflammatory Agents; Arthr | 1966 |
Assessment of drugs in out-patients with rheumatoid arthritis. Evaluation of methods and a comparison of mefenamic and flufenamic acids with phenylbutazone and aspirin.
Topics: Acetaminophen; Adult; Agglutination Tests; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; | 1967 |
Flufenamic acid in rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Guinea Pigs; Hu | 1967 |
Prostaglandins in the rheumatic diseases.
Topics: Arthritis, Rheumatoid; Aspirin; Bone Resorption; Cell Line; Colchicine; Cyclic AMP; Flufenamic Acid; | 1975 |
[Anti-inflammatory agents in current therapeutics].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1975 |
The place of mefenamic acid in the treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Flufenamic Acid; Humans; Mefenamic A | 1978 |
[Effect of antirheumatic agents on DNA-systems and DNA repair of various cell systems].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; DNA; DNA Repair; Flufenamic Acid; Humans; In Vitro | 1976 |
A sensitive method for the comparative bioassay of nonsteroidal anti-inflammatory compounds in adjuvant-induced primary inflammation in the rat.
Topics: Aminopyrine; Analysis of Variance; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin | 1975 |
[Topical use of Rheumon-Gel in the combined treatment of patients with rheumatoid arthritis].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Diclofenac; Drug Ev | 1987 |
Evaluation of euglobulin methods for the study of blood fibrinolytic activity: results for patients with rheumatoid arthritis and in the postoperative period.
Topics: Abdomen; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Chemical Fractionation; Complement C1 Inact | 1985 |
[Clinical studies on the use of a new combination of substances with antirheumatic action in the treatment of osteo-articular painful syndromes].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Back Pain; Cervical Vertebrae; Drug Combinations; Dru | 1974 |
Some metabolic and hormonal effects of flufenamic acid.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Albuminuria; Alcohols; Anti-Inflammatory Agents; Arthr | 1966 |
Method of treatment of rheumatoid arthritis in different countries.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chloroquine; | 1966 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
[In vivo investigation of the effect of antirheumatic drugs on DNA synthesis and DNA repair in patients with chronic rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Dimethylamines; DNA; DNA Repair; Female; Flufen | 1974 |
[Pharmacological study of phthalazino-(2,3-b)-phthalazine-5 (14H), 12(7H)-dione (L-5418)].
Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Barbiturates; Blood Co | 1974 |
[Therapy of chronic polyarthritis. 2].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Betamethasone; Dexamethasone; Flufenamic Ac | 1972 |
[Our experience with the new antirheumatic drug niflumic acid].
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Drug The | 1974 |
[Use of indomethacin in combination with other antirheumatic drugs in the therapy of chronic inflammatory rheumatism].
Topics: Arthritis, Rheumatoid; Aspirin; Chronic Disease; Dexamethasone; Drug Synergism; Flufenamic Acid; Gol | 1972 |
[The new anti-inflammatory acids. Niflumic acid in rheumatology].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid; | 1968 |
[Possibilities and limitations of an antirheumatic therapy].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Balneology; Drug Synergism; Electric Stimulation The | 1968 |
Discussion on clinical trials of the fenamates.
Topics: Analgesia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Central Nervous System; Flufena | 1966 |
Comparison of flufenamic acid with aspirin and paracetamol in terms of gastrointestinal blood loss.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chromium Isotopes; Fe | 1966 |
[Flufenamic acid in rheumatology].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Female; Flufenamic Acid; Gastritis; Gastrointestinal | 1970 |
[Therapy of progressive chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cortisone; Flufenamic Acid; Gold; Humans; Indoles; Mefenamic | 1970 |
[Clinical experience with the flufenamic acid--thyocolchicoside combination].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Colchicine; Flufenamic Acid; Fluorine; Glycosides; | 1970 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufen | 1968 |
[Flufenamic acid in the therapy of rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Flufenamic Acid; Fluorine; Hum | 1968 |
[Clinical evaluation of non-steroid anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Flufenamic Acid; Humans; Indomethacin; Inf | 1968 |
New drugs. VII. A controlled trial of flufenamic acid therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Female; Flufenamic Acid; Human | 1966 |
New drugs. 8. Flufenamic acid in rheumatoid arthritis. Comparison with aspirin and the results of extended treatment.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Diarrhea; Flufenamic | 1966 |