Page last updated: 2024-10-27

flufenamic acid and Anasarca

flufenamic acid has been researched along with Anasarca in 44 studies

Flufenamic Acid: An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
flufenamic acid : An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.

Research Excerpts

ExcerptRelevanceReference
" Finally, these active inhibitors of 5-lipoxygenase inhibited arachidonic acid-induced mouse ear edema more than phenidone."3.683,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors. ( Izumi, A; Matsumoto, H; Miki, T; Nihro, Y; Satoh, T; Sogawa, S; Ueda, H, 1993)
" Significant inhibition of oedema formation caused by thermal injury was observed for calcium carbaspirin, phenylbutazone, hydrocortisone, cryogenine and indomethacin when given daily beginning 2 days prior to thermal exposure and afterwards."3.65Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus. ( Malone, MH; Trottier, RW, 1973)
" The proven inhibition of inflammatory edema by chronic administration of Rheumon gel evidences the percutaneous absorption of the active principle through the intact skin."1.26[Pharmacology and toxicology of etofenamate. 1st Communication (author's transl)]. ( Breier, P; Dell, HD; Jacobi, H; Lorenz, D, 1977)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199039 (88.64)18.7374
1990's1 (2.27)18.2507
2000's0 (0.00)29.6817
2010's3 (6.82)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Nagakura, M1
Ota, T1
Shimidzu, N1
Kawamura, K1
Eto, Y1
Wada, Y1
Sogawa, S1
Nihro, Y1
Ueda, H1
Izumi, A1
Miki, T1
Matsumoto, H1
Satoh, T1
Theodosis-Nobelos, P2
Kourti, M2
Tziona, P1
Kourounakis, PN1
Rekka, EA2
Gavalas, A1
Alshehri, S1
Imam, SS1
Altamimi, MA1
Hussain, A1
Shakeel, F1
Alshehri, A1
Marto, J1
Baltazar, D1
Duarte, A1
Fernandes, A1
Gouveia, L1
Militão, M1
Salgado, A1
Simões, S1
Oliveira, E1
Ribeiro, HM1
Starr, MS1
West, GB1
Balestrieri, B1
Capasso, L1
Masiello, S1
Castaldo, S1
Capasso, F2
Nakamura, H2
Motoyoshi, S2
Seto, Y1
Imazu, C1
Kadokawa, T2
Shimizu, M2
Yokoyama, Y1
Sugishita, E1
Amagaya, S1
Ogihara, Y1
Jacobi, H1
Breier, P1
Dell, HD1
Lorenz, D1
Waterloh, E1
Groth, KH1
Ziel, R1
Krupp, P1
Horodniak, JW1
Matz, ED1
Walz, DT1
Sutton, BM1
Berkoff, CE1
Zarembo, JE1
Bender, AD1
Sorrentino, L1
Di Rosa, M1
Sauer, T1
Lehn, N1
Eitel, F1
Bauer, JA1
Vertuani, G1
Giori, P1
Guarneri, M1
Sarto, GP1
Wilhelmi, G2
Menassé-Gdynia, R1
Tsuji, H1
Aizawa, Y1
Iwasaki, M1
Domenjoz, R1
Mörsdorf, K1
Anspach, K1
Kobayashi, S1
Takagi, H1
Fregnan, GB1
Torsello, AL1
Brunet, S1
Fujimura, H2
Tsurumi, K5
Go, K1
Hiramatsu, Y4
Tamura, Y1
Nozaki, M3
Hayashi, M4
Yamaguchi, A2
Malone, MH1
Trottier, RW1
Nakano, K1
Wagner-Jauregg, T2
Jahn, U3
Bürlimann, W1
Shibuya, T2
Tamisier, JN1
Lamarche, M1
Pourel, J1
Louyot, P1
Kaump, DH1
Fischer, J1
Tanaka, K1
Iizuka, Y1
Marazzi-Uberti, E1
Lumachi, B1
Gaetani, M1
Coppi, G1
Bianchi, C1
Fujihira, E1
Otomo, S1
Sota, K1
Nakazawa, M1
Swingle, KF1
Hamilton, RR1
Harrington, JK1
Kvam, DC1
Földi-Börcsök, E1
Bedall, F1
Rahlfs, VW1
Artini, D1
Logemann, W1
Melloni, P1
Vita, G1
Buttinoni, A1
Tommasini, R1
Sancilio, LF1
Adrian, RW1

Trials

1 trial available for flufenamic acid and Anasarca

ArticleYear
[Experience with etofenamate in sport injuries (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:6B

    Topics: Adolescent; Adult; Ankle Injuries; Athletic Injuries; Drug Evaluation; Edema; Flufenamic Acid; Hemat

1977

Other Studies

43 other studies available for flufenamic acid and Anasarca

ArticleYear
Syntheses and antiinflammatory actions of 4,5,6,7-tetrahydroindazole-5-carboxylic acids.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Edema; Indazole

1979
3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.
    Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Cell Line; Chalcone; C

1993
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine ma

2015
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3

    Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hype

2016
Stimulatory Effects of Soluplus® on Flufenamic Acid β-Cyclodextrin Supramolecular Complex: Physicochemical Characterization and Pre-clinical Anti-inflammatory Assessment.
    AAPS PharmSciTech, 2020, May-19, Volume: 21, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Calorimetry, Differential Scan

2020
Topical gels of etofenamate: in vitro and in vivo evaluation.
    Pharmaceutical development and technology, 2015, Volume: 20, Issue:6

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Ethanol; Flufenami

2015
Bradykinin and oedema formation in heated paws of rats.
    British journal of pharmacology and chemotherapy, 1967, Volume: 31, Issue:1

    Topics: Animals; Aspirin; Bradykinin; Edema; Flufenamic Acid; Guinea Pigs; Histamine Release; Hot Temperatur

1967
[Scopolamine and its pharmacological effects on some experimental inflammation tests].
    La Clinica terapeutica, 1980, Jan-31, Volume: 92, Issue:2

    Topics: Animals; Carrageenan; Cellulose; Dextrans; Edema; Flufenamic Acid; Granuloma; Indomethacin; Inflamma

1980
[Effect of a transcutaneous non-steroidal anti-inflammatory agent, etofenamate gel, on mixed phlogistic-induced hind paw edema and traumatic edema].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1983, Volume: 103, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Edema; Flufenamic Acid; Gels; Male; Rats; Rats, Inbred Strains; W

1983
[Anti-edema activity of a trans-cutaneous non-steroidal anti-inflammatory agent, etofenamate gel, in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 80, Issue:2

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arthritis, Experim

1982
Anti-inflammatory testing methods: comparative evaluation of mice and rats.
    Journal of pharmacobio-dynamics, 1981, Volume: 4, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Cyproheptadine; Edema; Female;

1981
[Pharmacology and toxicology of etofenamate. 1st Communication (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:6B

    Topics: Animals; Drug Evaluation, Preclinical; Edema; Female; Flufenamic Acid; Guinea Pigs; Male; Mice; Rats

1977
The significance of inhibition of prostaglandin synthesis in the selection of non-steroidal anti-inflammatory agents.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Analgesia; Animals; Anti-Inflammatory Agents; Aspirin; Body Temperature; Cyclooxygenase Inhibitors;

1975
Inhibition of prostaglandin synthetase and carrageenan-induced edema by tricyclic analogs of flufenamic acid.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 11, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cattle; Cyclooxygenase Inhibitors; Edema; Flufenamic

1975
Anti-inflammatory properties of griseofulvin.
    Agents and actions, 1977, Volume: 7, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cell Migration Inhibition; Dose-Response Relationshi

1977
[Effect of etofenamate on early scald-induced edema. An experimental ultrasound study].
    Der Unfallchirurg, 1987, Volume: 90, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Edema; Female; Flufenamic Acid; Rats; Rats,

1987
Synthesis and anti-inflammatory and analgesic activities of 3-methyl-N-phenyl-1H-pyrazol-5-ylcarboxamides.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Edema; Flufenamic A

1985
Gastric mucosal damage induced by non-steroid anti-inflammatory agents in rats of different ages.
    Pharmacology, 1972, Volume: 8, Issue:4

    Topics: Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Body Weight; Dose-Response Relationship, Dr

1972
[Anti-inflammatory principle synthesized by a strain of Serratia sp].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, May-20, Volume: 65, Issue:3

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Aspirin; Bromelains; Carrageenan; Chymotrypsin; Ed

1969
[Relationship between the inhibition of ATPase activity and inflammatory edema by nonsteroid anti-inflammatory drugs. Approach to the screening test in vitro of nonsteroid anti-inflammatory drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Jul-20, Volume: 66, Issue:4

    Topics: Acetanilides; Adenosine Triphosphatases; Aminocaproates; Aminopyrine; Aminosalicylic Acids; Animals;

1970
[Pharmacology of antirheumatic drugs].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1969, Volume: 1

    Topics: Adenosine Triphosphate; Analgesics; Animals; Anti-Inflammatory Agents; Central Nervous System; Chemi

1969
[Efficacy of different antiphlogistic agents with respect to carrageenan-inflammation, compared with other models of inflammation].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:1

    Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; D

1971
Pharmacological studies of a new antiinflammatory compound, 2-phenyl-6-dimethylamino-6H-cycloheptoxazole.
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:10

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Carrageenan; Chloro

1968
Local anti-inflammatory properties of etoclofene. A new fenamate derivative.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Benzyl Co

1974
Species differences in susceptibility to the gastro-ulcerogenic action of anti-inflammatory agents.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Administration, Oral; Ambystoma; Animals; Anti-Inflammatory Agents; Cricetinae; Dose-Response Relati

1974
[Pharmacological study of phthalazino-(2,3-b)-phthalazine-5 (14H), 12(7H)-dione (L-5418)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:3

    Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Barbiturates; Blood Co

1974
[Pharmacological studies on niflumic acid, with special reference to the comparison with fenametes. 1. Anti-inflammatory and analgesic actions].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis; Capillary Permeability;

1972
Evaluation of cryogenine on rat paw thermal oedema and rat isolated uterus.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Benzocaine; Bradykinin; Burns; Chlorpromazine; Dose-Re

1973
[Pharmacological studies on N-benzoyl-N'-phenyl-2,6-diaminobenzoic acid (F-1). 1. Anti-inflammatory action].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:5

    Topics: Adrenal Glands; Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis; Ascorbic Acid; Aspirin; B

1973
[Antirheumatics with fibrinolytic properties. Comparison between compounds of the flufenamic acid series with trifluoromethyl analogues of azapropazone].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:7

    Topics: Analgesics; Aniline Compounds; Animals; Anti-Inflammatory Agents; Dimethylamines; Edema; Fibrinolysi

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 1. On acute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Edema; Electrolytes; Eryth

1973
[Anti-inflammatory action of N-(2,6-dichlorophenyl)-o-aminophenylacetic acid, its sodium salt, N-(2,6-dichlorophenyl)-anthranilic acid and its sodium salt. 2. On subacute inflammation].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1973, Volume: 69, Issue:2

    Topics: Acute Disease; Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis; Body Weight; Ed

1973
[Experimental results of combinations of nonsteroid anti-inflammatory agents in acute and chronic inflammation].
    Revue du rhumatisme et des maladies osteo-articulaires, 1974, Volume: 41, Issue:3

    Topics: Acute Disease; Animals; Arthritis; Carrageenan; Chronic Disease; Drug Therapy, Combination; Edema; F

1974
Experimental observations on flufenamic, mefanamic and meclofenamic acids. II. Toxicology in animals.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Aluminum; Animals; Anti-Inflammatory Agents; Calcium; Colon; Dogs; Edema; Female; Flufenamic Acid; F

1966
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agen

1970
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid;

1972
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 7. Pharmacological comparison with standard anti-inflammatory drugs.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Edema; Female; Fever; Flufenamic Acid; Indometh

1972
[Anti-inflammatory activities of compounds related to anthranilic acid. II. On acridine mono- and dicarboxylic, and oxo-acridan monocarboxylic acid derivatives].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1971, Volume: 91, Issue:2

    Topics: Acridines; Aminopyrine; Animals; Anti-Inflammatory Agents; Carboxylic Acids; Carrageenan; Cattle; Ch

1971
3-Benzoyldifluoromethanesulfonanilide, sodium salt (diflumidone sodium, MBR 4164-8): a new anti-inflammatory agent.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 189, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Benzoates; Car

1971
[The anti-inflammatory and anti-edematous effects of coumarins from Melilotus officinalis].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:12

    Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Arthritis; Coumarins; Edema; Flufenamic Aci

1971
[Analgesic and antiphlogistic action of amide and amine compounds. 1].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Amides; Amines; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Depression, Chemical; Ed

1970
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed

1969
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Bloo

1969