fludarabine phosphate has been researched along with Leucocythaemia in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Appelhans, D; Gorzkiewicz, M; Jatczak-Pawlik, I; Klajnert-Maculewicz, B; Pułaski, Ł; Studzian, M; Voit, B | 1 |
| Czarnik, AC; Dai, Y; Grant, S; Kramer, LB; Maggio, SC; Paik, DS; Payne, SG; Rahmani, M; Rosato, RR; Spiegel, S | 1 |
| Bosanquet, AG | 1 |
| Brown, KR; Chen, S; Choi, BY; Lin, ZY; Skalski, V | 1 |
| Gandhi, V; Plunkett, W | 1 |
| Balcerzak, S; Grever, M; Kraut, E; Leiby, J; Malspeis, L; Metz, E; Neidhart, J | 1 |
| Cheson, BD | 1 |
| Cheson, BD; Chun, HG; Leyland-Jones, B | 1 |
| Catapano, CV; Chandler, KB; Fernandes, DJ | 1 |
| Berman, E; Warrell, RP | 1 |
| Caryk, SM; Chun, HG; Hoth, DF; Leyland-Jones, BR | 1 |
| Cabanillas, F; Danhauser, L; Keating, M; Plunkett, W | 1 |
3 review(s) available for fludarabine phosphate and Leucocythaemia
| Article | Year |
|---|---|
Cellular and clinical pharmacology of fludarabine.
Topics: Antineoplastic Agents; Biological Availability; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Evaluation, Preclinical; Humans; Leukemia; Lymphoma; Phosphorylation; Vidarabine; Vidarabine Phosphate | 2002 |
Issues for the future development of fludarabine phosphate.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Drug Evaluation; Humans; Infusions, Intravenous; Leukemia; Lymphoproliferative Disorders; Vidarabine Phosphate | 1990 |
Fludarabine phosphate: a synthetic purine antimetabolite with significant activity against lymphoid malignancies.
Topics: Antimetabolites, Antineoplastic; Humans; Leukemia; Neoplasms; Vidarabine Phosphate | 1991 |
2 trial(s) available for fludarabine phosphate and Leucocythaemia
| Article | Year |
|---|---|
A comprehensive phase I and II clinical investigation of fludarabine phosphate.
Topics: Adult; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Neoplasms; Vidarabine Phosphate | 1990 |
Fludarabine phosphate: a synthetic purine antimetabolite with significant activity against lymphoid malignancies.
Topics: Antimetabolites, Antineoplastic; Humans; Leukemia; Neoplasms; Vidarabine Phosphate | 1991 |
8 other study(ies) available for fludarabine phosphate and Leucocythaemia
| Article | Year |
|---|---|
Glycodendrimer Nanocarriers for Direct Delivery of Fludarabine Triphosphate to Leukemic Cells: Improved Pharmacokinetics and Pharmacodynamics of Fludarabine.
Topics: Dendrimers; Drug Carriers; Humans; Leukemia; THP-1 Cells; U937 Cells; Vidarabine Phosphate | 2018 |
The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Caspases; Cell Cycle; Cell Cycle Proteins; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histones; Humans; Jurkat Cells; Leukemia; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitochondria; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reactive Oxygen Species; S Phase; Tumor Necrosis Factor-alpha; U937 Cells; Vidarabine Phosphate | 2004 |
Re: V.I. Avramis et al., Pharmacokinetic and pharmacodynamic studies of fludarabine and cytosine arabinoside administered as loading boluses followed by continuous infusions after a Phase I/II study in pediatric patients with relapsed leukemias. Clin. Can
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Humans; Leukemia; Terminology as Topic; Vidarabine; Vidarabine Phosphate | 1999 |
A 3'-5' exonuclease in human leukemia cells: implications for resistance to 1-beta -D-arabinofuranosylcytosine and 9-beta -D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate.
Topics: Antimetabolites, Antineoplastic; Arabinonucleotides; Cell Nucleus; Cells, Cultured; Cytidine Monophosphate; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Exodeoxyribonuclease V; Exodeoxyribonucleases; Exonucleases; Humans; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphocytes; Magnesium; Neoplasm Proteins; Potassium Chloride; Protein Biosynthesis; Time Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation; Vidarabine Phosphate | 2000 |
Inhibition of primer RNA formation in CCRF-CEM leukemia cells by fludarabine triphosphate.
Topics: Aphidicolin; Arabinofuranosylcytosine Triphosphate; Deoxyguanine Nucleotides; Diterpenes; DNA Primase; DNA-Directed DNA Polymerase; DNA, Neoplasm; Humans; Leukemia; RNA; RNA Nucleotidyltransferases; Tumor Cells, Cultured; Vidarabine Phosphate | 1991 |
Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity.
Topics: Acute Disease; Adult; Arabinonucleotides; Central Nervous System; Drug Evaluation; Humans; Infusions, Parenteral; Leukemia; Leukemia, Lymphoid; Middle Aged; Nervous System Diseases; Vidarabine Phosphate | 1986 |
Central nervous system toxicity of fludarabine phosphate.
Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Arabinonucleotides; Blindness; Brain Diseases; Central Nervous System Diseases; Child; Drug Evaluation; Electroencephalography; Female; Humans; Leukemia; Male; Middle Aged; Tomography, X-Ray Computed; Vidarabine Phosphate; Vision Disorders | 1986 |
9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate pharmacokinetics in plasma and tumor cells of patients with relapsed leukemia and lymphoma.
Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; DNA; Humans; Kinetics; Leukemia; Lymphoma; Vidarabine Phosphate | 1986 |