fludarabine and Leukemia L 1210

fludarabine has been researched along with Leukemia L 1210 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montgomery, JA; Secrist, JA; Shortnacy, AT1
King, I; Li, Z; Liu, L; Song, BL; Zheng, LM1
Brockman, RW; Cheng, YC; Montgomery, JA; Schabel, FM1
Cory, JG; Montgomery, JA; Sato, A1
Chello, PL; Dorick, DM; Montgomery, JA; Sirotnak, FM1
Chello, PL; Dorick, DM; Montgomery, JA; Sirotnak, FM; Yang, CH1
Bennett, LL; Brockman, RW; Shaddix, SC; White, EL1
Brockman, RW; El Dareer, SM; Hill, DL; Kirk, MC; Montgomery, JA; Shortnacy, AT; Struck, RF; Thorpe, MC1
Fabianowska-Majewska, K; Wyczechowska, D1
Adjei, AA; Dagnino, L; Paterson, AR; Wong, MM1
Barrueco, JR; Brockman, RW; Chang, CH; Jacobsen, DM; Sirotnak, FM1
Bacon, PE; Brown, NC; Carter, GL; Cory, JG; Montgomery, JA; Sato, A1

Other Studies

12 other study(ies) available for fludarabine and Leukemia L 1210

ArticleYear
2-Fluoroformycin and 2-aminoformycin. Synthesis and biological activity.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:11

    Topics: Adenosine; Adenosine Deaminase; Animals; Antibiotics, Antineoplastic; Formycins; Kinetics; Leukemia L1210; Nucleotides; Phosphates; Substrate Specificity

1985
Anti-tumor efficacy of Cloretazine (VNP40101M) alone and in combination with fludarabine in murine tumor and human xenograft tumor models.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:1

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Injections, Intraperitoneal; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Sulfonamides; Survival Analysis; Time Factors; Tumor Burden; Vidarabine; Weight Loss; Xenograft Model Antitumor Assays

2007
Metabolism and chemotherapeutic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase.
    Cancer research, 1980, Volume: 40, Issue:10

    Topics: Animals; Cell Line; Chromatography, DEAE-Cellulose; Deoxycytidine Kinase; DNA; Electrophoresis, Polyacrylamide Gel; Leukemia L1210; Mice; Mutation; Oxidative Phosphorylation; Phosphotransferases; Vidarabine

1980
Synergistic inhibition of leukemia L1210 cell growth in vitro by combinations of 2-fluoroadenine nucleosides and hydroxyurea or 2,3-dihydro-1H-pyrazole[2,3-a]imidazole.
    Cancer research, 1984, Volume: 44, Issue:8

    Topics: Animals; Cell Survival; Cytidine; Deferoxamine; Deoxyadenosines; Deoxycytidine; Drug Synergism; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Pyrazoles; Vidarabine

1984
Specificity of systems mediating transport of adenosine, 9-beta-d-arabinofuranosyl-2-fluoroadenine, and other purine nucleoside analogues in L1210 cells.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Adenosine; Animals; Biological Transport; Kinetics; Leukemia L1210; Mice; Purine Nucleosides; Temperature; Time Factors; Vidarabine

1983
Initial rate kinetics and evidence for duality of mediated transport of adenosine, related purine nucleosides, and nucleoside analogues in L1210 cells.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Adenosine; Animals; Biological Transport; Cell Membrane; Kinetics; Leukemia L1210; Mice; Purine Nucleosides; Temperature; Time Factors; Vidarabine

1983
Comparison of the actions of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine on target enzymes from mouse tumor cells.
    Cancer research, 1982, Volume: 42, Issue:6

    Topics: Adenosylhomocysteinase; Animals; DNA Polymerase I; DNA Polymerase II; DNA Replication; Hydrolases; Leukemia L1210; Mice; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases; Vidarabine

1982
Identification of metabolites of 9-beta-D-arabinofuranosyl-2-fluoroadenine, an antitumor and antiviral agent.
    Biochemical pharmacology, 1982, Jun-01, Volume: 31, Issue:11

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Chemical Phenomena; Chemistry; Dogs; Female; Leukemia L1210; Macaca mulatta; Male; Mice; Vidarabine

1982
Does 2-chlorodeoxyadenosine contribute to alteration of DNA methyltransferase activity?
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosylhomocysteinase; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Cladribine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Hydrolases; Kinetics; Leukemia L1210; Mice; Tumor Cells, Cultured; Vidarabine

1998
Protection against fludarabine neurotoxicity in leukemic mice by the nucleoside transport inhibitor nitrobenzylthioinosine.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Hindlimb; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Nervous System Diseases; Paralysis; Prodrugs; Thioinosine; Thionucleotides; Vidarabine

1992
Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.
    Cancer research, 1987, Feb-01, Volume: 47, Issue:3

    Topics: Animals; Biological Transport; Epithelium; Intestine, Small; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Organ Specificity; Phosphorylation; Tritium; Vidarabine

1987
The utility of combinations of drugs directed at specific sites of the same target enzyme--ribonucleotide reductase as the model.
    Advances in enzyme regulation, 1985, Volume: 23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cells, Cultured; Deoxyadenosines; Deoxyguanosine; Hydroxyurea; Isoquinolines; Leukemia L1210; Models, Biological; Nucleic Acid Synthesis Inhibitors; Phosphorylases; Pyrazoles; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thymidine; Vidarabine

1985