flucytosine has been researched along with Recrudescence in 40 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Excerpt | Relevance | Reference |
---|---|---|
"One hundred ninety-four patients with cryptococcal meningitis were enrolled in a multicenter, prospective, randomized clinical trial to compare the efficacy and toxicity of four as compared with six weeks of combination amphotericin B and flucytosine therapy." | 9.06 | Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks. ( Blackwelder, WC; Bowles, CA; Cloud, G; Craven, PC; Diasio, RB; Dismukes, WE; Fisher, JF; Gallis, HA; Gregg, CR; Kaplowitz, LG; Kaufman, L; Kerkering, TM; Medoff, G; Shadomy, S; Soong, S; Stamm, AM, 1987) |
"An antifungal agent (Flucytosine) was used to treat urinary candidiasis in 9 patients who had an indwelling catheter and developed fungal colony counts greater than 10(4)." | 7.67 | [Clinical efficacy of flucytosine on urinary candidiasis]. ( Asakawa, M; Kakinoki, K; Kawashima, H; Mori, K; Tanaka, S; Tsurusaki, K; Umeda, M; Yasumoto, R, 1988) |
"Intravenous miconazole, an investigational, broad-spectrum, antifungal imidazole drug, was clinically effective when used for the first time in a patient with life-threatening sporotrichosis." | 7.65 | Pulmonary sporotrichosis: Treatment with miconazole. ( Archer, G; Rohwedder, JJ, 1976) |
"In patients with the acquired immunodeficiency syndrome (AIDS), the rate of relapse after primary treatment for cryptococcal meningitis remains high." | 6.67 | A placebo-controlled trial of maintenance therapy with fluconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome. California Collaborative Treatment Group. ( Bozzette, SA; Chiu, J; Gilbert, G; Jacobsen, J; Larsen, RA; Leal, MA; McCutchan, JA; Robinson, P; Rothman, P; Tilles, J, 1991) |
"One hundred ninety-four patients with cryptococcal meningitis were enrolled in a multicenter, prospective, randomized clinical trial to compare the efficacy and toxicity of four as compared with six weeks of combination amphotericin B and flucytosine therapy." | 5.06 | Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks. ( Blackwelder, WC; Bowles, CA; Cloud, G; Craven, PC; Diasio, RB; Dismukes, WE; Fisher, JF; Gallis, HA; Gregg, CR; Kaplowitz, LG; Kaufman, L; Kerkering, TM; Medoff, G; Shadomy, S; Soong, S; Stamm, AM, 1987) |
" We examined four issues: the efficacy of treatment with amphotericin plus flucytosine as compared with amphotericin alone, the efficacy of suppressive therapy, the prognostic clinical characteristics, and the course of nonmeningeal cryptococcosis." | 3.67 | Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome. ( Chuck, SL; Sande, MA, 1989) |
"In an attempt to decrease the risk for reactivation of life-threatening invasive aspergillosis (IA) during subsequent myelosuppression in patients with previously diagnosed IA who were receiving antileukemic treatment, we evaluated the role of intensive antifungal therapy with amphotericin B and 5-fluorocytosine administered prophylactically throughout the antileukemic regimen and induced granulocytopenia to prevent IA reactivation without compromising the intensive chemotherapy." | 3.67 | An approach to intensive antileukemia therapy in patients with previous invasive aspergillosis. ( Burch, PA; Karp, JE; Merz, WG, 1988) |
"An antifungal agent (Flucytosine) was used to treat urinary candidiasis in 9 patients who had an indwelling catheter and developed fungal colony counts greater than 10(4)." | 3.67 | [Clinical efficacy of flucytosine on urinary candidiasis]. ( Asakawa, M; Kakinoki, K; Kawashima, H; Mori, K; Tanaka, S; Tsurusaki, K; Umeda, M; Yasumoto, R, 1988) |
"A 50-year-old woman with cryptococcal meningitis was treated with amphotericin B intrathecally through a Rickham reservoir and intravenously, together with flucytosine orally." | 3.66 | Cryptococcal meningitis: complications due to intrathecal treatment. ( Esmann, V; Schønheyder, H; Stenderup, A; Thestrup-Pedersen, K, 1980) |
"Intravenous miconazole, an investigational, broad-spectrum, antifungal imidazole drug, was clinically effective when used for the first time in a patient with life-threatening sporotrichosis." | 3.65 | Pulmonary sporotrichosis: Treatment with miconazole. ( Archer, G; Rohwedder, JJ, 1976) |
"In patients with the acquired immunodeficiency syndrome (AIDS), the rate of relapse after primary treatment for cryptococcal meningitis remains high." | 2.67 | A placebo-controlled trial of maintenance therapy with fluconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome. California Collaborative Treatment Group. ( Bozzette, SA; Chiu, J; Gilbert, G; Jacobsen, J; Larsen, RA; Leal, MA; McCutchan, JA; Robinson, P; Rothman, P; Tilles, J, 1991) |
" The proper duration and dosage and the combination of antifungal drugs have not been clearly defined." | 2.38 | [Primary Aspergillus endocarditis. Apropos of a case and review of the international literature]. ( Cajot, MA; Gosselin, B; Goullard, L; Koussa, A; Marquette, F; Pol, A; Roux, JP; Soots, G; Warembourg, H, 1992) |
"He had multiple prior episodes of cryptococcal meningitis with complications necessitating ventriculoperitoneal shunt placement and was on suppressive fluconazole when he developed worsening brain manifestations." | 1.56 | Case Report: A Case of Severe Cryptococcal Immune Reconstitution Inflammatory Syndrome Presenting with Brain and Intradural Abscesses in an HIV Patient. ( Jeng, A; Kalinoski, T; Malenfant, J; Yim, C, 2020) |
"parapsilosis infection without recurrence was confirmed." | 1.36 | Candida parapsilosis meningitis associated with shunt infection in an adult male. ( Bagheri, F; Cervellione, KL; Marino, W; Maruf, M; Santucci, T, 2010) |
"Cryptococcal meningitis is a common cause of chronic meningitis in Papua New Guinea, affecting apparently immunocompetent people." | 1.29 | Cryptococcal meningitis (C. neoformans var. gattii) leading to blindness in previously healthy Melanesian adults in Papua New Guinea. ( Fisher, D; Lalloo, D; Laurenson, I; Mavo, B; Naraqi, S; Saweri, A; Sinha, A; Temu, P, 1994) |
" Because amphotericin B nephrotoxicity was suspected, further intravenous administration was stopped after a cumulative dosage of 2 g." | 1.28 | [Cryptococcal meningitis in AIDS: successful long-term prophylaxis with fluconazole]. ( Glück, T; Weber, P; Wiedmann, KH, 1991) |
"In 2 cases recurrences occurred (6,66 por 100)." | 1.27 | [Chromomycosis. Treatment with a combination of thiabendazole and 5-fluorocytosine, 6-year follow-up]. ( Castro, A; Hidalgo, H; Montero-Gei, F; Solano, E, 1983) |
"Cryptococcal meningitis is a life-threatening disease." | 1.27 | [Cryptococcal meningitis]. ( Biniek, R; Hilgenstock, F; Schuchardt, V, 1986) |
"Peritonitis was usually treated with intraperitoneal administration of cefazolin sodium, and 61% of the episodes were treated at home." | 1.27 | Peritonitis in children undergoing continuous ambulatory peritoneal dialysis. ( Calvin, S; Luis, ES; McDaid, T; Potter, D; Powell, D, 1985) |
"Successful treatment of fungal endocarditis is being described with increasing frequency." | 1.26 | Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported. ( Galgiani, JN; Stevens, DA, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 19 (47.50) | 18.7374 |
1990's | 10 (25.00) | 18.2507 |
2000's | 4 (10.00) | 29.6817 |
2010's | 5 (12.50) | 24.3611 |
2020's | 2 (5.00) | 2.80 |
Authors | Studies |
---|---|
Kalinoski, T | 1 |
Malenfant, J | 1 |
Yim, C | 1 |
Jeng, A | 1 |
Xue, X | 1 |
Deng, H | 1 |
Zhao, L | 1 |
Zang, X | 1 |
Asuquo, IP | 1 |
Meng, M | 1 |
Ma, X | 1 |
Qin, C | 1 |
Meng, Y | 1 |
Wu, C | 1 |
Gao, J | 1 |
Pan, L | 1 |
Chiron, LM | 1 |
Pihet, M | 1 |
Rouleau, F | 1 |
de Gentile, L | 1 |
Bouchara, JP | 1 |
Chabasse, D | 1 |
Chung, T | 1 |
Na, J | 1 |
Kim, YI | 2 |
Chang, DY | 1 |
Kim, H | 1 |
Moon, HE | 1 |
Kang, KW | 1 |
Lee, DS | 1 |
Chung, JK | 1 |
Kim, SS | 1 |
Suh-Kim, H | 1 |
Paek, SH | 1 |
Youn, H | 1 |
Pérez Melón, C | 1 |
Conde Rivera, O | 1 |
Novoa Fernández, E | 1 |
Borrajo Prol, M | 1 |
Bagheri, F | 1 |
Cervellione, KL | 1 |
Maruf, M | 1 |
Marino, W | 1 |
Santucci, T | 1 |
Hamoud, S | 1 |
Keidar, Z | 1 |
Hayek, T | 1 |
Kresch, ZA | 1 |
Espinosa-Heidmann, D | 1 |
Harper, T | 1 |
Jamie Miller, G | 1 |
Shann, S | 1 |
Wilson, J | 1 |
Martínez-Baltanás, A | 1 |
Cuadrado, JM | 1 |
Jover, F | 1 |
Roig, P | 1 |
Thompson, HJ | 1 |
Samelson, LE | 1 |
Lerner, SA | 1 |
Resnekov, L | 1 |
Anagnostopoulos, C | 1 |
Solano, E | 1 |
Hidalgo, H | 1 |
Castro, A | 1 |
Montero-Gei, F | 1 |
Schønheyder, H | 1 |
Thestrup-Pedersen, K | 1 |
Esmann, V | 1 |
Stenderup, A | 1 |
Hietala, SO | 1 |
Jonsson, M | 1 |
Burman, LA | 1 |
Lalloo, D | 1 |
Fisher, D | 1 |
Naraqi, S | 1 |
Laurenson, I | 1 |
Temu, P | 1 |
Sinha, A | 1 |
Saweri, A | 1 |
Mavo, B | 1 |
Offner, F | 1 |
Cordonnier, C | 1 |
Ljungman, P | 1 |
Prentice, HG | 1 |
Engelhard, D | 1 |
De Bacquer, D | 1 |
Meunier, F | 1 |
De Pauw, B | 1 |
Alonso, M | 1 |
García, F | 1 |
Mallolas, J | 1 |
Soriano, A | 1 |
Ortega, M | 1 |
Miró, JM | 1 |
Gatell, JM | 1 |
Soriano, E | 1 |
Kirsch, LS | 1 |
Brownstein, S | 1 |
Deschênes, J | 1 |
Sorgini, C | 1 |
Jackson, WB | 1 |
Codish, SD | 1 |
Monaco, AP | 1 |
Galgiani, JN | 1 |
Stevens, DA | 1 |
Rohwedder, JJ | 1 |
Archer, G | 1 |
Wise, GJ | 1 |
Goldberg, P | 1 |
Kozinn, PJ | 1 |
Nawabi, IU | 1 |
Roux, JP | 1 |
Koussa, A | 1 |
Cajot, MA | 1 |
Marquette, F | 1 |
Goullard, L | 1 |
Gosselin, B | 1 |
Pol, A | 1 |
Warembourg, H | 1 |
Soots, G | 1 |
Larsen, RA | 2 |
Glück, T | 1 |
Weber, P | 1 |
Wiedmann, KH | 1 |
Bozzette, SA | 1 |
Chiu, J | 1 |
Leal, MA | 1 |
Jacobsen, J | 1 |
Rothman, P | 1 |
Robinson, P | 1 |
Gilbert, G | 1 |
McCutchan, JA | 1 |
Tilles, J | 1 |
Nelson, MR | 1 |
Bower, M | 1 |
Smith, D | 1 |
Reed, C | 1 |
Shanson, D | 1 |
Gazzard, B | 1 |
Mitchell, DM | 1 |
Fitz-Henley, M | 1 |
Horner-Bryce, J | 1 |
Chuck, SL | 1 |
Sande, MA | 1 |
Karp, JE | 1 |
Burch, PA | 1 |
Merz, WG | 1 |
Schmutzhard, E | 1 |
Vejajjiva, A | 1 |
Yasumoto, R | 1 |
Asakawa, M | 1 |
Umeda, M | 1 |
Tanaka, S | 1 |
Tsurusaki, K | 1 |
Mori, K | 1 |
Kakinoki, K | 1 |
Kawashima, H | 1 |
Dismukes, WE | 1 |
Cloud, G | 1 |
Gallis, HA | 1 |
Kerkering, TM | 1 |
Medoff, G | 1 |
Craven, PC | 1 |
Kaplowitz, LG | 1 |
Fisher, JF | 1 |
Gregg, CR | 1 |
Bowles, CA | 1 |
Shadomy, S | 1 |
Stamm, AM | 1 |
Diasio, RB | 1 |
Kaufman, L | 1 |
Soong, S | 1 |
Blackwelder, WC | 1 |
Horowitz, BJ | 1 |
Zuger, A | 1 |
Louie, E | 1 |
Holzman, RS | 1 |
Simberkoff, MS | 1 |
Rahal, JJ | 1 |
Biniek, R | 1 |
Hilgenstock, F | 1 |
Schuchardt, V | 1 |
Powell, D | 1 |
Luis, ES | 1 |
Calvin, S | 1 |
McDaid, T | 1 |
Potter, D | 1 |
Hill, HR | 1 |
Mitchell, TG | 1 |
Matsen, JM | 1 |
Quie, PG | 1 |
Hoeprich, PD | 1 |
Ingraham, JL | 1 |
Kleker, E | 1 |
Winship, MJ | 1 |
3 reviews available for flucytosine and Recrudescence
Article | Year |
---|---|
Cryptococcosis caused by cryptococcus gattii: 2 case reports and literature review.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Asian Peopl | 2020 |
Not your "typical patient": cryptococcal meningitis in an immunocompetent patient.
Topics: Amphotericin B; Antifungal Agents; Biopsy, Needle; Consciousness Disorders; Fatigue; Flucytosine; He | 2005 |
[Primary Aspergillus endocarditis. Apropos of a case and review of the international literature].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Combined Modality Therapy; | 1992 |
2 trials available for flucytosine and Recrudescence
Article | Year |
---|---|
A placebo-controlled trial of maintenance therapy with fluconazole after treatment of cryptococcal meningitis in the acquired immunodeficiency syndrome. California Collaborative Treatment Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Cryptococcosis; Double-Blind Method; Drug Evaluatio | 1991 |
Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Antigens, Fungal; Child; Clinical Trials | 1987 |
35 other studies available for flucytosine and Recrudescence
Article | Year |
---|---|
Case Report: A Case of Severe Cryptococcal Immune Reconstitution Inflammatory Syndrome Presenting with Brain and Intradural Abscesses in an HIV Patient.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Anti-Inflammatory Agents; Anti-Retroviral Agents | 2020 |
[Comment on this case report].
Topics: Adult; Amphotericin B; Antifungal Agents; Buprenorphine; Candidiasis; Endocarditis; Endophthalmitis; | 2012 |
Dihydropyrimidine Dehydrogenase Is a Prognostic Marker for Mesenchymal Stem Cell-Mediated Cytosine Deaminase Gene and 5-Fluorocytosine Prodrug Therapy for the Treatment of Recurrent Gliomas.
Topics: Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Cytosine Deaminase; Dihydrouracil Dehy | 2016 |
[Candida-induced recurrent peritonitis after peritoneal catheter reinsertion].
Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Candidiasis; Catheter-Related Infections; Device Rem | 2009 |
Candida parapsilosis meningitis associated with shunt infection in an adult male.
Topics: Amphotericin B; Antifungal Agents; Brain Abscess; Candida; Candidiasis; Drainage; Fluconazole; Flucy | 2010 |
Recurrent Saccharomyces cerevisiae fungemia in an otherwise healthy patient.
Topics: Abdominal Pain; Adult; Amphotericin B; Antifungal Agents; Chills; Diagnosis, Differential; Female; F | 2011 |
Disseminated Cryptococcus with ocular cryptococcoma in a human immunodeficiency virus-negative patient.
Topics: Amphotericin B; Anemia, Hemolytic, Autoimmune; Antifungal Agents; Cryptococcosis; Cryptococcus; Drug | 2012 |
Treatment of Candida glabrata using topical amphotericin B and flucytosine.
Topics: Administration, Intravaginal; Adult; Amphotericin B; Antifungal Agents; Candidiasis, Vulvovaginal; D | 2003 |
[Meningeal cryptococcosis as a sign of immune reconstitution syndrome].
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; An | 2005 |
Relapse of Candida parapsilosis endocarditis after long-term suppression with flucytosin: retreatment with valve replacement and ketoconazole.
Topics: Adult; Amphotericin B; Candidiasis; Cytosine; Drug Therapy, Combination; Endocarditis; Female; Flucy | 1980 |
[Chromomycosis. Treatment with a combination of thiabendazole and 5-fluorocytosine, 6-year follow-up].
Topics: Adult; Aged; Agricultural Workers' Diseases; Chromoblastomycosis; Cytosine; Drug Evaluation; Drug Th | 1983 |
Cryptococcal meningitis: complications due to intrathecal treatment.
Topics: Amphotericin B; Catheterization; Cryptococcosis; Drug Therapy, Combination; Female; Flucytosine; Hum | 1980 |
Candida albicans pneumonia.
Topics: Adult; Aged; Bronchopneumonia; Candidiasis; Diagnosis, Differential; Female; Flucytosine; Humans; Lu | 1982 |
Cryptococcal meningitis (C. neoformans var. gattii) leading to blindness in previously healthy Melanesian adults in Papua New Guinea.
Topics: Adolescent; Adult; Amphotericin B; Blindness; Child; Cryptococcus neoformans; Female; Flucytosine; H | 1994 |
Impact of previous aspergillosis on the outcome of bone marrow transplantation.
Topics: Amphotericin B; Anemia, Aplastic; Antifungal Agents; Aspergillosis; Bone Marrow Transplantation; Flu | 1998 |
[Disseminated cryptococcosis in patients with AIDS. Prognostic factors of poor outcome].
Topics: Acute Disease; Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Amphotericin B; Analy | 1999 |
Saccharomyces keratitis and endophthalmitis.
Topics: Aged; Amphotericin B; Anterior Chamber; Antifungal Agents; Cornea; Endophthalmitis; Eye Infections, | 1999 |
Case report: immunosuppressive therapy following Cryptococcal meningitis.
Topics: Adult; Amphotericin B; Cryptococcosis; Female; Flucytosine; Humans; Immunosuppression Therapy; Kidne | 1976 |
Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported.
Topics: Adult; Amphotericin B; Aortic Valve Stenosis; Candidiasis; Cytosine; Endocarditis; Flucytosine; Hear | 1977 |
Pulmonary sporotrichosis: Treatment with miconazole.
Topics: Amphotericin B; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Therapy, Combinat | 1976 |
Agranulocytosis associated with flucytosine for urinary candidiasis.
Topics: Aged; Agranulocytosis; Candidiasis; Cytosine; Cytotoxicity Tests, Immunologic; Drug Hypersensitivity | 1976 |
Suppressive therapy for cryptococcal meningitis.
Topics: Amphotericin B; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Meningitis, Cryptococca | 1992 |
[Cryptococcal meningitis in AIDS: successful long-term prophylaxis with fluconazole].
Topics: Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Antigens, Bacterial; Cryptococcus; Drug T | 1991 |
The value of serum cryptococcal antigen in the diagnosis of cryptococcal infection in patients infected with the human immunodeficiency virus.
Topics: Amphotericin B; Antigens, Fungal; Cryptococcosis; Cryptococcus neoformans; Flucytosine; HIV Infectio | 1990 |
A case of disseminated phaeohyphomycosis caused by Cladosporium devriesii.
Topics: Adult; Amphotericin B; Cause of Death; Cladosporium; Female; Flucytosine; Humans; Mycoses; Recurrenc | 1990 |
Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Amphotericin B; Cryptococcosis; Cryptococcus neofor | 1989 |
An approach to intensive antileukemia therapy in patients with previous invasive aspergillosis.
Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Drug Therapy, | 1988 |
Treatment of cryptococcal meningitis with high-dose, long-term combination amphotericin B and flucytosine.
Topics: Administration, Oral; Adolescent; Adult; Amphotericin B; Cryptococcosis; Drug Therapy, Combination; | 1988 |
[Clinical efficacy of flucytosine on urinary candidiasis].
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Candida; Candidiasis; Drug Evaluation; Fema | 1988 |
Topical flucytosine therapy for chronic recurrent Candida tropicalis infections.
Topics: Candidiasis; Chronic Disease; Female; Flucytosine; Humans; Recurrence; Vaginal Creams, Foams, and Je | 1986 |
Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Diagnostic features and outcome of treatment.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Brain Diseases; Cryptococcosis; Drug Ther | 1986 |
[Cryptococcal meningitis].
Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcosis; Drug Resistance, Microbial; Drug Therapy, | 1986 |
Peritonitis in children undergoing continuous ambulatory peritoneal dialysis.
Topics: Adolescent; Adult; Amphotericin B; Anti-Bacterial Agents; Cefazolin; Child; Child, Preschool; Drug T | 1985 |
Recovery from disseminated candidiasis in a premature neonate.
Topics: Amphotericin B; Antifungal Agents; Arthritis, Infectious; Candidiasis; Cytosine; Drug Resistance, Mi | 1974 |
Development of resistance to 5-fluorocytosine in Candida parapsilosis during therapy.
Topics: Adult; Aminohydrolases; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Cell-Free System; C | 1974 |