flucytosine has been researched along with Optic Nerve Glioma in 1 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Optic Nerve Glioma: Glial cell derived tumors arising from the optic nerve, usually presenting in childhood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast, CD-UPRT-expressing tumors had increased CD gene activity with a threefold higher intratumoral accumulation of 5FU and significant generation of F-nucs." | 1.32 | The use of 19F spectroscopy and diffusion-weighted MRI to evaluate differences in gene-dependent enzyme prodrug therapies. ( Chen, M; Chenevert, TL; Dornfeld, KJ; Gelovani, JT; Hamstra, DA; Lawrence, TS; Lee, KC; Moffat, BA; Rehemtulla, A; Ross, BD; Schepkin, VD; Tychewicz, JM, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamstra, DA | 1 |
| Lee, KC | 1 |
| Tychewicz, JM | 1 |
| Schepkin, VD | 1 |
| Moffat, BA | 1 |
| Chen, M | 1 |
| Dornfeld, KJ | 1 |
| Lawrence, TS | 1 |
| Chenevert, TL | 1 |
| Ross, BD | 1 |
| Gelovani, JT | 1 |
| Rehemtulla, A | 1 |
1 other study available for flucytosine and Optic Nerve Glioma
| Article | Year |
|---|---|
The use of 19F spectroscopy and diffusion-weighted MRI to evaluate differences in gene-dependent enzyme prodrug therapies.
Topics: Animals; Antineoplastic Agents; Artificial Gene Fusion; Brain; Cytosine Deaminase; Diffusion Magneti | 2004 |