flucytosine has been researched along with Neoplasm Metastasis in 3 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a hepatic metastasis model, mice treated with an intravenous administration of both AdCD (2 x 10(8) pfu) and an intermediate dose of AdmIL-2 (1 x 10(6) pfu) demonstrated the most significant reduction of metastatic foci and the longest survival following a 5-FC administration." | 1.31 | Dose of adenoviral vectors expressing interleukin-2 plays an important role in combined gene therapy with cytosine deaminase/5-fluorocytosine: preclinical consideration. ( Hamada, H; Iwahashi, M; Nakamori, M; Terasawa, H; Tsunoda, T; Ueda, K; Yamaue, H, 2002) |
| "The growth of the human colon cancer cells was quantified by dot blot analysis of genomic DNA extracted from tumor-bearing liver, hybridized with a human-specific Alu probe." | 1.29 | Regional delivery of an adenovirus vector containing the Escherichia coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver. ( Crystal, RG; Hirschowitz, EA; Ohwada, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gavelli, A | 1 |
| Baqué, P | 1 |
| Brossettej, N | 1 |
| Bourgeon, A | 1 |
| Staccini, P | 1 |
| Rossi, B | 1 |
| Pierrefite-Carle, V | 1 |
| Ohwada, A | 1 |
| Hirschowitz, EA | 1 |
| Crystal, RG | 1 |
| Nakamori, M | 1 |
| Iwahashi, M | 1 |
| Ueda, K | 1 |
| Tsunoda, T | 1 |
| Terasawa, H | 1 |
| Hamada, H | 1 |
| Yamaue, H | 1 |
3 other studies available for flucytosine and Neoplasm Metastasis
| Article | Year |
|---|---|
Per os administration of 5-fluorocytosine is effective in the regression of CD-expressing liver metastases in rats.
Topics: Administration, Oral; Animals; Antimetabolites; Cancer Vaccines; Cell Line, Tumor; Cytosine Deaminas | 2004 |
Regional delivery of an adenovirus vector containing the Escherichia coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver.
Topics: Animals; Antineoplastic Agents; Blotting, Northern; Cell Division; Colonic Neoplasms; Cytosine Deami | 1996 |
Dose of adenoviral vectors expressing interleukin-2 plays an important role in combined gene therapy with cytosine deaminase/5-fluorocytosine: preclinical consideration.
Topics: Adenoviridae; Animals; Antimetabolites; Combined Modality Therapy; Cytosine Deaminase; Escherichia c | 2002 |