flucytosine has been researched along with Melanoma in 10 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (10.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (50.00) | 29.6817 |
2010's | 2 (20.00) | 24.3611 |
2020's | 2 (20.00) | 2.80 |
Authors | Studies |
---|---|
Allende, JB | 1 |
Finocchiaro, LME | 1 |
Glikin, GC | 1 |
Jakubechova, J | 1 |
Smolkova, B | 1 |
Furdova, A | 1 |
Demkova, L | 1 |
Altanerova, U | 1 |
Nicodemou, A | 1 |
Zeleznikova, T | 1 |
Klimova, D | 1 |
Altaner, C | 1 |
Liu, S | 1 |
Song, W | 1 |
Liu, F | 1 |
Zhang, J | 1 |
Zhu, S | 1 |
Kaufmann, JK | 1 |
Bossow, S | 1 |
Grossardt, C | 1 |
Sawall, S | 1 |
Kupsch, J | 1 |
Erbs, P | 1 |
Hassel, JC | 1 |
von Kalle, C | 1 |
Enk, AH | 1 |
Nettelbeck, DM | 1 |
Ungerechts, G | 1 |
Dabrowska, A | 1 |
Szary, J | 1 |
Kowalczuk, M | 1 |
Szala, S | 1 |
Ugorski, M | 1 |
Liu, Y | 2 |
Ye, T | 1 |
Sun, D | 1 |
Maynard, J | 1 |
Deisseroth, A | 2 |
An, LN | 1 |
Li, ZH | 1 |
Yue, Y | 1 |
Wang, SR | 1 |
Guo, ZY | 1 |
Zamboni, S | 1 |
Mallano, A | 1 |
Flego, M | 1 |
Ascione, A | 1 |
Dupuis, ML | 1 |
Gellini, M | 1 |
Barca, S | 1 |
Cianfriglia, M | 1 |
Roth, EF | 1 |
McKitrick, JC | 1 |
Herz, F | 1 |
10 other studies available for flucytosine and Melanoma
Article | Year |
---|---|
Therapeutic potential of the cytosine deaminase::uracil phosphoribosyl transferase/5-fluorocytosine suicide system for canine melanoma.
Topics: Animals; Cell Death; Cytosine Deaminase; Dog Diseases; Dogs; Flucytosine; Melanoma; Pentosyltransfer | 2022 |
Suicide-Gene-Modified Extracellular Vesicles of Human Primary Uveal Melanoma in Future Therapies.
Topics: Animals; Extracellular Vesicles; Flucytosine; Fluorouracil; Humans; Melanoma; Skin Neoplasms; Uveal | 2023 |
Antitumor efficacy of VP22-CD/5-FC suicide gene system mediated by lentivirus in a murine uveal melanoma model.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Cytosine Deaminase; Disease Models, Animal; Flow Cytom | 2018 |
Chemovirotherapy of malignant melanoma with a targeted and armed oncolytic measles virus.
Topics: Animals; Antigens, Neoplasm; Antimetabolites; Biopsy; Cell Line, Tumor; Chlorocebus aethiops; Combin | 2013 |
CEA-negative glioblastoma and melanoma cells are sensitive to cytosine deaminase/5-fluorocytosine therapy directed by the carcinoembryonic antigen promoter.
Topics: Base Sequence; Carcinoembryonic Antigen; Cell Line, Tumor; Cytosine Deaminase; DNA, Complementary; D | 2004 |
Tumor-specific therapeutic effect induced by an oncolytic adenoviral vector containing heat shock protein 70 and prodrug activation genes.
Topics: Adenoviridae; Adenovirus E1A Proteins; Animals; Antimetabolites; Cell Line, Tumor; Combined Modality | 2006 |
Oncolytic adenoviral vector carrying the cytosine deaminase gene for melanoma gene therapy.
Topics: Adenoviridae; Animals; Blotting, Western; Cell Line, Tumor; Cytosine Deaminase; DNA Primers; Flucyto | 2006 |
[Gene therapy for melanoma by bifidobacterium infantis-mediated transfer of CD and UPRT genes with 5-FC in vitro].
Topics: Animals; Bifidobacterium; Cell Line, Tumor; Culture Media, Conditioned; Cytosine Deaminase; Flucytos | 2007 |
Genetic construction, expression, and characterization of a single chain anti-CEA antibody fused to cytosine deaminase from yeast.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Apoptosis; Blotting, Western; Carcinoembryonic Antigen; | 2008 |
The use of 5-fluorocytosine and ketoconazole in the culture of the erythrocytic stages of Plasmodium falciparum and some tumor cell lines.
Topics: Animals; Cell Line; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Erythrocytes; Fe | 1989 |