flucytosine and Lupus Erythematosus, Systemic
flucytosine has been researched along with Lupus Erythematosus, Systemic in 11 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" Long term administration of amphotericin B (cumulative dose 5 g) combined with 5-flucytosine eradicated this fungal infection." | 5.28 | [A case of systemic lupus erythematosus associated with cryptococcal meningitis which was successfully cured by the administration of massive dose of amphotericin B]. ( Chida, Y; Hiruma, M; Ida, T; Makiguchi, K; Malumo, F; Matsuda, O; Tsutsui, H, 1990) |
"A case of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) associated with pulmonary cryptococcosis which was successfully treated with fluconazole (FCZ) and flucytosine (5-FC) is described." | 4.78 | [A case report--pulmonary cryptococcosis associated with systemic lupus erythematosus and review of 44 cases in Japan]. ( Kano, S; Minato, N; Saito, K; Saito, T; Saku, N; Sato, M; Suzuki, N; Takeda, A, 1993) |
"This is a case report of fatal cryptococcal meningitis in a child with systemic lupus erythematosus being treated with prednisolone and azathioprine." | 3.68 | Cryptococcal meningitis in a child with systemic lupus erythematosus. ( al-Fawaz, IM; al-Rasheed, SA, 1990) |
"Patients with systemic lupus erythematosus (SLE) complicated with cryptococcal meningitis (CM) are easy to be misdiagnosed as neuropsychiatric lupus or tuberculous meningitis due to the lack of specificity of clinical symptoms, which may delay treatment." | 1.91 | Systemic lupus erythematosus complicated with cryptococcal meningitis: A case report. ( Du, L; Liu, J; Ma, H; Wang, X; Wang, Y, 2023) |
" Ventricular drainage and amphotericin B intraventricularly via an implanted tube into dilated ventricle could improve the clinical condition of serious cryptococcal meningitis and decrease the dosage of systemic use of amphotericin B, therefore, reduce the side-effects of the drugs." | 1.31 | [A clinical study of 26 cases of cryptococcal meningitis]. ( Li, T; Liu, Z; Qin, S; Sheng, R; Wang, A, 2002) |
"Sixty days after the treatment, thrombocytopenia was observed with positive lupus anticoagulant and anticardiolipin antibody." | 1.31 | [A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis]. ( Izumi, Y; Kameyama, M; Sakoda, H; Udaka, F, 2001) |
"Two cases of cryptococcal meningitis occurring in patients with systemic lupus erythematosus (SLE) are presented, and 24 additional cases from the literature are reviewed." | 1.28 | Cryptococcal meningitis in systemic lupus erythematosus. ( Lally, EV; Spiegel, M; Zimmermann, B, 1992) |
" Long term administration of amphotericin B (cumulative dose 5 g) combined with 5-flucytosine eradicated this fungal infection." | 1.28 | [A case of systemic lupus erythematosus associated with cryptococcal meningitis which was successfully cured by the administration of massive dose of amphotericin B]. ( Chida, Y; Hiruma, M; Ida, T; Makiguchi, K; Malumo, F; Matsuda, O; Tsutsui, H, 1990) |
" Cryptococcemia was strongly associated with corticosteroid therapy, especially when the dosage had recently been increased." | 1.27 | Cryptococcemia. ( Durack, DT; Gallis, HA; Perfect, JR, 1983) |
Research
Studies (11)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (36.36) | 18.7374 |
1990's | 4 (36.36) | 18.2507 |
2000's | 2 (18.18) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (9.09) | 2.80 |
Authors
Authors | Studies |
---|---|
Ma, H | 1 |
Wang, Y | 2 |
Liu, J | 1 |
Du, L | 1 |
Wang, X | 1 |
Liu, Z | 1 |
Wang, A | 1 |
Li, T | 1 |
Qin, S | 1 |
Sheng, R | 1 |
Perfect, JR | 1 |
Durack, DT | 1 |
Gallis, HA | 1 |
Fathizadeh, A | 1 |
Rippon, JW | 1 |
Rosenfeld, SI | 1 |
Fretzin, DF | 1 |
Lorincz, AL | 1 |
Sato, M | 1 |
Saku, N | 1 |
Takeda, A | 2 |
Suzuki, N | 1 |
Saito, T | 1 |
Minato, N | 1 |
Saito, K | 1 |
Kano, S | 2 |
Izumi, Y | 1 |
Sakoda, H | 1 |
Udaka, F | 1 |
Kameyama, M | 1 |
Speller, DC | 1 |
Fakunle, F | 1 |
Cairns, SA | 1 |
Stephens, M | 1 |
Zimmermann, B | 1 |
Spiegel, M | 1 |
Lally, EV | 1 |
al-Rasheed, SA | 1 |
al-Fawaz, IM | 1 |
Matsuda, O | 1 |
Hiruma, M | 1 |
Makiguchi, K | 1 |
Tsutsui, H | 1 |
Chida, Y | 1 |
Ida, T | 1 |
Malumo, F | 1 |
Kimura, K | 1 |
Hatakeyama, M | 1 |
Miyagi, J | 1 |
Sumiya, M | 1 |
Takaku, F | 1 |
Yamamoto, K | 1 |
Reviews
1 review available for flucytosine and Lupus Erythematosus, Systemic
Article | Year |
---|---|
[A case report--pulmonary cryptococcosis associated with systemic lupus erythematosus and review of 44 cases in Japan].
Topics: Arthritis, Rheumatoid; Cryptococcosis; Drug Therapy, Combination; Female; Fluconazole; Flucytosine; | 1993 |
Other Studies
10 other studies available for flucytosine and Lupus Erythematosus, Systemic
Article | Year |
---|---|
Systemic lupus erythematosus complicated with cryptococcal meningitis: A case report.
Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Female; Flucytosine; Humans; Lupu | 2023 |
[A clinical study of 26 cases of cryptococcal meningitis].
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Amphotericin B; Child; Cryptococcus; Drainage | 2002 |
Cryptococcemia.
Topics: Adrenal Cortex Hormones; Adult; Aged; Amphotericin B; Cryptococcosis; Cryptococcus neoformans; Femal | 1983 |
Pheomycotic cyst in an immunosuppressed host.
Topics: Aged; Cysts; Dermatomycoses; Female; Flucytosine; Humans; Immunosuppression Therapy; Leukemia, Lymph | 1981 |
[A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis].
Topics: Adult; Amphotericin B; Antifungal Agents; Antiphospholipid Syndrome; Female; Flucytosine; Humans; Im | 2001 |
Cryptococcal meningitis complicating systemic lupus erythematosus: two patients treated with flucytosine and amphotericin B.
Topics: Amphotericin B; Cryptococcosis; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Fem | 1977 |
Cryptococcal meningitis in systemic lupus erythematosus.
Topics: Adult; Amphotericin B; Cryptococcus; Female; Flucytosine; Humans; Lupus Erythematosus, Systemic; Men | 1992 |
Cryptococcal meningitis in a child with systemic lupus erythematosus.
Topics: Amphotericin B; Azathioprine; Cerebrospinal Fluid; Child; Cryptococcosis; Diagnosis, Differential; F | 1990 |
[A case of systemic lupus erythematosus associated with cryptococcal meningitis which was successfully cured by the administration of massive dose of amphotericin B].
Topics: Adult; Amphotericin B; Cryptococcosis; Drug Therapy, Combination; Flucytosine; Humans; Infusions, In | 1990 |
[A case of systemic lupus erythematosus with cryptococcal meningitis successfully treated with amphotericin B and 5-FC].
Topics: Adult; Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Female; Flucytosine; Hum | 1986 |