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flucytosine and Lupus Erythematosus, Systemic

flucytosine has been researched along with Lupus Erythematosus, Systemic in 11 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
" Long term administration of amphotericin B (cumulative dose 5 g) combined with 5-flucytosine eradicated this fungal infection."5.28[A case of systemic lupus erythematosus associated with cryptococcal meningitis which was successfully cured by the administration of massive dose of amphotericin B]. ( Chida, Y; Hiruma, M; Ida, T; Makiguchi, K; Malumo, F; Matsuda, O; Tsutsui, H, 1990)
"A case of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) associated with pulmonary cryptococcosis which was successfully treated with fluconazole (FCZ) and flucytosine (5-FC) is described."4.78[A case report--pulmonary cryptococcosis associated with systemic lupus erythematosus and review of 44 cases in Japan]. ( Kano, S; Minato, N; Saito, K; Saito, T; Saku, N; Sato, M; Suzuki, N; Takeda, A, 1993)
"This is a case report of fatal cryptococcal meningitis in a child with systemic lupus erythematosus being treated with prednisolone and azathioprine."3.68Cryptococcal meningitis in a child with systemic lupus erythematosus. ( al-Fawaz, IM; al-Rasheed, SA, 1990)
"Patients with systemic lupus erythematosus (SLE) complicated with cryptococcal meningitis (CM) are easy to be misdiagnosed as neuropsychiatric lupus or tuberculous meningitis due to the lack of specificity of clinical symptoms, which may delay treatment."1.91Systemic lupus erythematosus complicated with cryptococcal meningitis: A case report. ( Du, L; Liu, J; Ma, H; Wang, X; Wang, Y, 2023)
" Ventricular drainage and amphotericin B intraventricularly via an implanted tube into dilated ventricle could improve the clinical condition of serious cryptococcal meningitis and decrease the dosage of systemic use of amphotericin B, therefore, reduce the side-effects of the drugs."1.31[A clinical study of 26 cases of cryptococcal meningitis]. ( Li, T; Liu, Z; Qin, S; Sheng, R; Wang, A, 2002)
"Sixty days after the treatment, thrombocytopenia was observed with positive lupus anticoagulant and anticardiolipin antibody."1.31[A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis]. ( Izumi, Y; Kameyama, M; Sakoda, H; Udaka, F, 2001)
"Two cases of cryptococcal meningitis occurring in patients with systemic lupus erythematosus (SLE) are presented, and 24 additional cases from the literature are reviewed."1.28Cryptococcal meningitis in systemic lupus erythematosus. ( Lally, EV; Spiegel, M; Zimmermann, B, 1992)
" Long term administration of amphotericin B (cumulative dose 5 g) combined with 5-flucytosine eradicated this fungal infection."1.28[A case of systemic lupus erythematosus associated with cryptococcal meningitis which was successfully cured by the administration of massive dose of amphotericin B]. ( Chida, Y; Hiruma, M; Ida, T; Makiguchi, K; Malumo, F; Matsuda, O; Tsutsui, H, 1990)
" Cryptococcemia was strongly associated with corticosteroid therapy, especially when the dosage had recently been increased."1.27Cryptococcemia. ( Durack, DT; Gallis, HA; Perfect, JR, 1983)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Ma, H1
Wang, Y2
Liu, J1
Du, L1
Wang, X1
Liu, Z1
Wang, A1
Li, T1
Qin, S1
Sheng, R1
Perfect, JR1
Durack, DT1
Gallis, HA1
Fathizadeh, A1
Rippon, JW1
Rosenfeld, SI1
Fretzin, DF1
Lorincz, AL1
Sato, M1
Saku, N1
Takeda, A2
Suzuki, N1
Saito, T1
Minato, N1
Saito, K1
Kano, S2
Izumi, Y1
Sakoda, H1
Udaka, F1
Kameyama, M1
Speller, DC1
Fakunle, F1
Cairns, SA1
Stephens, M1
Zimmermann, B1
Spiegel, M1
Lally, EV1
al-Rasheed, SA1
al-Fawaz, IM1
Matsuda, O1
Hiruma, M1
Makiguchi, K1
Tsutsui, H1
Chida, Y1
Ida, T1
Malumo, F1
Kimura, K1
Hatakeyama, M1
Miyagi, J1
Sumiya, M1
Takaku, F1
Yamamoto, K1

Reviews

1 review available for flucytosine and Lupus Erythematosus, Systemic

ArticleYear
[A case report--pulmonary cryptococcosis associated with systemic lupus erythematosus and review of 44 cases in Japan].
    Ryumachi. [Rheumatism], 1993, Volume: 33, Issue:1

    Topics: Arthritis, Rheumatoid; Cryptococcosis; Drug Therapy, Combination; Female; Fluconazole; Flucytosine;

1993

Other Studies

10 other studies available for flucytosine and Lupus Erythematosus, Systemic

ArticleYear
Systemic lupus erythematosus complicated with cryptococcal meningitis: A case report.
    Medicine, 2023, Apr-14, Volume: 102, Issue:15

    Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Female; Flucytosine; Humans; Lupu

2023
[A clinical study of 26 cases of cryptococcal meningitis].
    Zhonghua nei ke za zhi, 2002, Volume: 41, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Amphotericin B; Child; Cryptococcus; Drainage

2002
Cryptococcemia.
    Medicine, 1983, Volume: 62, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amphotericin B; Cryptococcosis; Cryptococcus neoformans; Femal

1983
Pheomycotic cyst in an immunosuppressed host.
    Journal of the American Academy of Dermatology, 1981, Volume: 5, Issue:4

    Topics: Aged; Cysts; Dermatomycoses; Female; Flucytosine; Humans; Immunosuppression Therapy; Leukemia, Lymph

1981
[A case of SLE presenting the features of antiphospholipid antibody syndrome during a treatment for complicated cryptococcal meningitis].
    No to shinkei = Brain and nerve, 2001, Volume: 53, Issue:7

    Topics: Adult; Amphotericin B; Antifungal Agents; Antiphospholipid Syndrome; Female; Flucytosine; Humans; Im

2001
Cryptococcal meningitis complicating systemic lupus erythematosus: two patients treated with flucytosine and amphotericin B.
    Journal of clinical pathology, 1977, Volume: 30, Issue:3

    Topics: Amphotericin B; Cryptococcosis; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Fem

1977
Cryptococcal meningitis in systemic lupus erythematosus.
    Seminars in arthritis and rheumatism, 1992, Volume: 22, Issue:1

    Topics: Adult; Amphotericin B; Cryptococcus; Female; Flucytosine; Humans; Lupus Erythematosus, Systemic; Men

1992
Cryptococcal meningitis in a child with systemic lupus erythematosus.
    Annals of tropical paediatrics, 1990, Volume: 10, Issue:3

    Topics: Amphotericin B; Azathioprine; Cerebrospinal Fluid; Child; Cryptococcosis; Diagnosis, Differential; F

1990
[A case of systemic lupus erythematosus associated with cryptococcal meningitis which was successfully cured by the administration of massive dose of amphotericin B].
    Nihon Jinzo Gakkai shi, 1990, Volume: 32, Issue:4

    Topics: Adult; Amphotericin B; Cryptococcosis; Drug Therapy, Combination; Flucytosine; Humans; Infusions, In

1990
[A case of systemic lupus erythematosus with cryptococcal meningitis successfully treated with amphotericin B and 5-FC].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1986, Volume: 75, Issue:3

    Topics: Adult; Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Female; Flucytosine; Hum

1986
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