flucytosine has been researched along with Lung Neoplasms in 16 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The majority of brain metastases result from lung cancer, but the metastatic mechanism remains unclear." | 1.38 | Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor-tropic properties. ( Cho, MH; Choi, KC; Kim, SU; Kim, YB; Lee, HJ; Yi, BR, 2012) |
| "In a novel experimental brain metastases model, intravenously administered F3 cells migrated near lung cancer metastatic lesions, which were induced by the injection of lung cancer cells via the intracarotid artery." | 1.38 | Neural stem cell-based dual suicide gene delivery for metastatic brain tumors. ( Ito, M; Iwami, K; Kim, SU; Kinjo, S; Lee, HJ; Momota, H; Motomura, K; Natsume, A; Nishimira, Y; Ohka, F; Ohno, M; Wakabayashi, T; Wang, C, 2012) |
| " The dosing schedule required 30 days; neither addition of an enzyme inhibitor that increases the half-life of fluorocytosine nor intralumenal drug delivery is effective in shortening (to 15 days) the protocol." | 1.30 | Toxin gene-mediated growth inhibition of lung adenocarcinoma in an animal model of pleural malignancy. ( Batra, RK; Boucher, RC; Hoganson, DK; Matsui, H, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 2 |
| Ju, HZ | 1 |
| Yang, MF | 1 |
| Hwang, Y | 1 |
| Kim, D | 1 |
| Chang, D | 1 |
| Ahn, B | 1 |
| Kim, YB | 3 |
| Kim, G | 1 |
| Khatri, A | 1 |
| Husaini, Y | 1 |
| Ow, K | 1 |
| Chapman, J | 1 |
| Russell, PJ | 1 |
| Yuan, M | 1 |
| Deng, J | 1 |
| Wang, Z | 1 |
| Yang, W | 1 |
| Li, G | 1 |
| Ren, B | 1 |
| Yi, BR | 2 |
| O, SN | 1 |
| Kang, NH | 1 |
| Hwang, KA | 1 |
| Kim, SU | 3 |
| Jeung, EB | 1 |
| Heo, GJ | 1 |
| Choi, KC | 2 |
| Qiu, Y | 1 |
| Peng, GL | 1 |
| Liu, QC | 1 |
| Li, FL | 1 |
| Zou, XS | 1 |
| He, JX | 1 |
| Lee, HJ | 2 |
| Cho, MH | 1 |
| Michaelsen, SR | 1 |
| Christensen, CL | 1 |
| Sehested, M | 1 |
| Cramer, F | 1 |
| Poulsen, TT | 1 |
| Patterson, AV | 1 |
| Poulsen, HS | 1 |
| Zarogoulidis, P | 1 |
| Chatzaki, E | 1 |
| Hohenforst-Schmidt, W | 1 |
| Goldberg, EP | 1 |
| Galaktidou, G | 1 |
| Kontakiotis, T | 1 |
| Karamanos, N | 1 |
| Zarogoulidis, K | 1 |
| Wang, C | 1 |
| Natsume, A | 1 |
| Motomura, K | 1 |
| Nishimira, Y | 1 |
| Ohno, M | 1 |
| Ito, M | 1 |
| Kinjo, S | 1 |
| Momota, H | 1 |
| Iwami, K | 1 |
| Ohka, F | 1 |
| Wakabayashi, T | 1 |
| Cao, HQ | 1 |
| Zhao, Y | 1 |
| Meng, XM | 1 |
| Ding, JF | 1 |
| Gavelli, A | 1 |
| Baqué, P | 1 |
| Brossettej, N | 1 |
| Bourgeon, A | 1 |
| Staccini, P | 1 |
| Rossi, B | 1 |
| Pierrefite-Carle, V | 1 |
| Hidaka, A | 1 |
| Hamaji, Y | 1 |
| Sasaki, T | 1 |
| Taniguchi, S | 1 |
| Fujimori, M | 1 |
| Hoganson, DK | 1 |
| Matsui, H | 1 |
| Batra, RK | 1 |
| Boucher, RC | 1 |
| Pauli, G | 1 |
| Dietemann-Molard, A | 1 |
| Pujol, JL | 1 |
| Roegel, E | 1 |
| Doutsu, Y | 1 |
| Masaki, M | 1 |
| Masuyama, Y | 1 |
| Yamashita, K | 1 |
| Oka, M | 1 |
| Koga, H | 1 |
| Kohno, S | 1 |
| Shigeno, Y | 1 |
| Kanda, T | 1 |
| Yamaguchi, K | 1 |
1 review available for flucytosine and Lung Neoplasms
| Article | Year |
|---|---|
Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review.
Topics: Adenoviridae; Aged; Anemia; Animals; Antimetabolites, Antineoplastic; Bystander Effect; Carcinoma, N | 2012 |
15 other studies available for flucytosine and Lung Neoplasms
| Article | Year |
|---|---|
Pulmonary cryptococcosis and cryptococcal osteomyelitis mimicking primary and metastatic lung cancer in (18)F-FDG PET/CT.
Topics: Adult; Amphotericin B; Cryptococcosis; Cryptococcus neoformans; Female; Flucytosine; Fluorodeoxygluc | 2014 |
Effects of neural stem cells and 5-fluorocytosine in canine metastatic lung tumor.
Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Dog Diseases; Dogs; Flucytosine; Genetic | 2017 |
Cytosine deaminase-uracil phosphoribosyltransferase and interleukin (IL)-12 and IL-18: a multimodal anticancer interface marked by specific modulation in serum cytokines.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Cytokines; Cyto | 2009 |
Combination therapy in A549 cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Combined Modality | 2010 |
Genetically engineered stem cells expressing cytosine deaminase and interferon-β migrate to human lung cancer cells and have potentially therapeutic anti-tumor effects.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Communication; Cell Line, Tumor; Cell Migration Assays; Cell Mo | 2011 |
Selective killing of lung cancer cells using carcinoembryonic antigen promoter and double suicide genes, thymidine kinase and cytosine deaminase (pCEA-TK/CD).
Topics: Apoptosis; Carcinoembryonic Antigen; Cell Cycle; Cell Line, Tumor; Cytosine Deaminase; Flucytosine; | 2012 |
Antitumor effects of genetically engineered stem cells expressing yeast cytosine deaminase in lung cancer brain metastases via their tumor-tropic properties.
Topics: Animals; Brain Neoplasms; Cell Survival; Cytosine Deaminase; Flucytosine; Fluorouracil; Genetic Engi | 2012 |
Single agent- and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Cytosine Deaminase; Dru | 2012 |
Neural stem cell-based dual suicide gene delivery for metastatic brain tumors.
Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Brain Neoplasms; Bystander Effect; Caro | 2012 |
[Killing effect of human pulmonary adenocarcinoma cells with TK + CD/5-Fc + GCV coexpression suicide gene systems].
Topics: Cell Line, Tumor; Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; Hu | 2001 |
Per os administration of 5-fluorocytosine is effective in the regression of CD-expressing liver metastases in rats.
Topics: Administration, Oral; Animals; Antimetabolites; Cancer Vaccines; Cell Line, Tumor; Cytosine Deaminas | 2004 |
Exogenous cytosine deaminase gene expression in Bifidobacterium breve I-53-8w for tumor-targeting enzyme/prodrug therapy.
Topics: Animals; Antineoplastic Agents; Bifidobacterium; Cell Line, Tumor; Cytosine Deaminase; Drug Delivery | 2007 |
Toxin gene-mediated growth inhibition of lung adenocarcinoma in an animal model of pleural malignancy.
Topics: Adenocarcinoma; Animals; Cell Division; Cytosine Deaminase; Disease Models, Animal; Escherichia coli | 1998 |
[Invasive aspergillar pneumopathy during the treatment of microcellular bronchial cancer. Efficacy of early antifungal treatment].
Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; As | 1985 |
[Clinical and therapeutic studies in eleven cases of primary pulmonary cryptococcosis].
Topics: Adolescent; Adult; Aged; Biopsy; Cryptococcosis; Diagnosis, Differential; Female; Flucytosine; Human | 1987 |