flucytosine has been researched along with Leukopenia in 3 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with flucytosine of 20 patients with fungal infections gave favorable results in four patients with crytococcal infections, two of four patients with disseminated candidiasis, eight of ten patients with urinary tract infections due to Candida albicans and Torulopsis glabrata, and tow of three patients with miscellaneous infections due to Calbicans." | 3.65 | Treatment of fungal infections with flucytosine. ( Harder, EJ; Hermans, PE, 1975) |
| " In three patients, accumulation of toxic levels of 5-FC was related to diminished renal function." | 1.26 | Bone marrow toxicity associated with 5-fluorocytosine therapy. ( Frame, PT; Kauffman, CA, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vermes, A | 1 |
| Guchelaar, HJ | 1 |
| van Kuilenburg, AB | 1 |
| Dankert, J | 1 |
| Kauffman, CA | 1 |
| Frame, PT | 1 |
| Harder, EJ | 1 |
| Hermans, PE | 1 |
1 trial available for flucytosine and Leukopenia
| Article | Year |
|---|---|
5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study.
Topics: Adult; Aged; beta-Alanine; Biotransformation; Bone Marrow; Candidiasis; Female; Flucytosine; Fluorou | 2002 |
2 other studies available for flucytosine and Leukopenia
| Article | Year |
|---|---|
Bone marrow toxicity associated with 5-fluorocytosine therapy.
Topics: Adult; Aged; Bone Marrow Diseases; Cytosine; Female; Flucytosine; Humans; Kidney Diseases; Leukopeni | 1977 |
Treatment of fungal infections with flucytosine.
Topics: Adult; Alkaline Phosphatase; Candida; Candida albicans; Candidiasis; Cryptococcosis; Cryptococcus ne | 1975 |