Page last updated: 2024-10-27

flucytosine and Leukocytopenia

flucytosine has been researched along with Leukocytopenia in 3 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Research Excerpts

ExcerptRelevanceReference
"Treatment with flucytosine of 20 patients with fungal infections gave favorable results in four patients with crytococcal infections, two of four patients with disseminated candidiasis, eight of ten patients with urinary tract infections due to Candida albicans and Torulopsis glabrata, and tow of three patients with miscellaneous infections due to Calbicans."3.65Treatment of fungal infections with flucytosine. ( Harder, EJ; Hermans, PE, 1975)
" In three patients, accumulation of toxic levels of 5-FC was related to diminished renal function."1.26Bone marrow toxicity associated with 5-fluorocytosine therapy. ( Frame, PT; Kauffman, CA, 1977)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vermes, A1
Guchelaar, HJ1
van Kuilenburg, AB1
Dankert, J1
Kauffman, CA1
Frame, PT1
Harder, EJ1
Hermans, PE1

Trials

1 trial available for flucytosine and Leukocytopenia

ArticleYear
5-fluorocytosine-related bone-marrow depression and conversion to fluorouracil: a pilot study.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:1

    Topics: Adult; Aged; beta-Alanine; Biotransformation; Bone Marrow; Candidiasis; Female; Flucytosine; Fluorou

2002

Other Studies

2 other studies available for flucytosine and Leukocytopenia

ArticleYear
Bone marrow toxicity associated with 5-fluorocytosine therapy.
    Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:2

    Topics: Adult; Aged; Bone Marrow Diseases; Cytosine; Female; Flucytosine; Humans; Kidney Diseases; Leukopeni

1977
Treatment of fungal infections with flucytosine.
    Archives of internal medicine, 1975, Volume: 135, Issue:2

    Topics: Adult; Alkaline Phosphatase; Candida; Candida albicans; Candidiasis; Cryptococcosis; Cryptococcus ne

1975