flucytosine has been researched along with Leucocythaemia in 18 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment." | 7.68 | Hepatosplenic candidiasis: successful treatment with fluconazole. ( Bradley, SF; Kauffman, CA; Ross, SC; Weber, DR, 1991) |
| "We present six cases of fusariosis caused by Fusarium solani that were diagnosed over a three-year period in 166 adult patients undergoing chemotherapy for acute leukemia." | 4.77 | Diagnosis and successful treatment of fusariosis in the compromised host. ( Hoagland, M; Hood, AF; Jett-Goheen, M; Junkins, JM; Karp, JE; Merz, WG, 1988) |
| "To determine if fluconazole is effective treatment for hepatosplenic candidiasis that has not resolved with amphotericin B and flucytosine treatment." | 3.68 | Hepatosplenic candidiasis: successful treatment with fluconazole. ( Bradley, SF; Kauffman, CA; Ross, SC; Weber, DR, 1991) |
| "Over 80 percent of patients with invasive pulmonary aspergillosis (IPA) undergoing intensive antileukemic chemotherapy in a recent two-year period survived the pulmonary infection as a result of early diagnosis and aggressive therapy with high-dose amphotericin B and 5-fluorocytosine." | 3.67 | Invasive pulmonary aspergillosis in acute leukemia. The contribution of CT to early diagnosis and aggressive management. ( Burch, PA; Fishman, EK; Karp, JE; Kuhlman, JE; Siegelman, SS; Zerhouni, EA, 1987) |
| "Two different flucytosine (5-FC) treatment regimens, one by itself and the other in combination with fluconazole (FLCZ) were compared in chemotherapy against mycotic infections in 60 patients with hematological diseases." | 2.67 | [A comparative clinical study on flucytosine alone and in combination with fluconazole in hematological malignancies: a multicenter study using the envelope method]. ( Ariyoshi, H; Hamajima, N; Hotta, T; Kodera, Y; Murate, T; Naito, K; Naoe, T; Ogura, M; Saito, H; Tanaka, M, 1994) |
| " Liposomal Amphotericin B allowing higher dosage by lower toxicity appears effective as salvage treatment especially in aspergillosis which also responds to Itraconazole available as oral formulation so far." | 2.38 | Antifungal treatment strategy in leukemia patients. ( Büchner, T; Roos, N, 1992) |
| "Intestinal candidiasis is uncommon and poorly characterized." | 1.27 | Esophageal, gastric, and intestinal candidiasis. ( Bjorkman, DJ; Trier, JS, 1984) |
| "15 of 16 cases with septicemia at autopsy had terminal fever." | 1.26 | Causes of death in leukemia and lymphoma with modern treatment. ( Adolfsson, J; Lagerlöf, B; Lantz, B; Reizenstein, P, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, GT | 1 |
| Heo, JR | 1 |
| Kim, SU | 1 |
| Choi, KC | 1 |
| Dong, XY | 1 |
| Wang, WQ | 1 |
| Zhao, Y | 1 |
| Li, XD | 1 |
| Fang, ZG | 1 |
| Lin, DJ | 1 |
| Xiao, RZ | 1 |
| Huang, RW | 1 |
| Pan, GJ | 1 |
| Liu, JJ | 1 |
| Kontoyiannis, DP | 1 |
| Trier, JS | 1 |
| Bjorkman, DJ | 1 |
| Lantz, B | 1 |
| Adolfsson, J | 1 |
| Lagerlöf, B | 1 |
| Reizenstein, P | 1 |
| Kurrle, E | 1 |
| Bhaduri, S | 1 |
| Krieger, D | 1 |
| Pflieger, H | 1 |
| Heimpel, H | 1 |
| Naito, K | 1 |
| Murate, T | 1 |
| Hotta, T | 1 |
| Saito, H | 1 |
| Hamajima, N | 1 |
| Naoe, T | 1 |
| Ogura, M | 1 |
| Ariyoshi, H | 1 |
| Tanaka, M | 1 |
| Kodera, Y | 1 |
| Wingard, JR | 1 |
| Merz, WG | 2 |
| Rinaldi, MG | 1 |
| Miller, CB | 1 |
| Karp, JE | 3 |
| Saral, R | 1 |
| Fouassier, M | 1 |
| Joly, D | 1 |
| Cambon, M | 1 |
| Peigue-Lafeuille, H | 1 |
| Condat, P | 1 |
| Myoken, Y | 2 |
| Sugata, T | 1 |
| Kyo, T | 1 |
| Fujihara, M | 1 |
| Mikami, Y | 1 |
| Sinclair, AJ | 1 |
| Rossof, AH | 1 |
| Coltman, CA | 1 |
| Krick, JA | 1 |
| Remington, JS | 1 |
| Büchner, T | 1 |
| Roos, N | 1 |
| Kauffman, CA | 1 |
| Bradley, SF | 1 |
| Ross, SC | 1 |
| Weber, DR | 1 |
| Wolf, HH | 1 |
| Scharf, RE | 1 |
| Arning, M | 1 |
| Schneider, W | 1 |
| Hoagland, M | 1 |
| Jett-Goheen, M | 1 |
| Junkins, JM | 1 |
| Hood, AF | 1 |
| Kuhlman, JE | 1 |
| Fishman, EK | 1 |
| Burch, PA | 1 |
| Zerhouni, EA | 1 |
| Siegelman, SS | 1 |
| Bodey, GP | 1 |
| Luna, M | 1 |
5 reviews available for flucytosine and Leucocythaemia
| Article | Year |
|---|---|
Invasive mycoses: strategies for effective management.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Antifungal Agents; Antineoplastic Agents; Asparta | 2012 |
[Geotrichum capitatum infection in a neutropenic patient. Apropos of a case and review of the literature].
Topics: Acute Disease; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Drug Combinations; Fatal Ou | 1998 |
Opportunistic invasive fungal infections in patients with leukaemia lymphoma.
Topics: Acute Disease; Adrenal Cortex Hormones; Amphotericin B; Aspergillosis; Blood Transfusion; Candidiasi | 1976 |
Antifungal treatment strategy in leukemia patients.
Topics: Amphotericin B; Antifungal Agents; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Itra | 1992 |
Diagnosis and successful treatment of fusariosis in the compromised host.
Topics: Adult; Amphotericin B; Female; Flucytosine; Fusarium; Humans; Immune Tolerance; Leukemia; Leukemia, | 1988 |
2 trials available for flucytosine and Leucocythaemia
| Article | Year |
|---|---|
Antimicrobial prophylaxis in acute leukaemia: prospective randomized study comparing two methods of selective decontamination.
Topics: Acute Disease; Adolescent; Adult; Aged; Aminoglycosides; Amphotericin B; Anti-Bacterial Agents; Bact | 1983 |
[A comparative clinical study on flucytosine alone and in combination with fluconazole in hematological malignancies: a multicenter study using the envelope method].
Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Fluconazole; Flucytosine; Glucans | 1994 |
11 other studies available for flucytosine and Leucocythaemia
| Article | Year |
|---|---|
The growth of K562 human leukemia cells was inhibited by therapeutic neural stem cells in cellular and xenograft mouse models.
Topics: Animals; Coculture Techniques; Cytosine Deaminase; Female; Flucytosine; Genetic Engineering; Genetic | 2018 |
Antibody-directed double suicide gene therapy targeting of MUC1- positive leukemia cells in vitro and in vivo.
Topics: Animals; Apoptosis; Cell Proliferation; Cytosine Deaminase; Disease Models, Animal; Flucytosine; Gan | 2013 |
Esophageal, gastric, and intestinal candidiasis.
Topics: Candidiasis; Deglutition Disorders; Diagnosis, Differential; Esophageal Diseases; Flucytosine; Human | 1984 |
Causes of death in leukemia and lymphoma with modern treatment.
Topics: Agranulocytosis; Bone Marrow; Escherichia coli; Female; Flucytosine; Heart Failure; Humans; Leukemia | 1980 |
Association of Torulopsis glabrata infections with fluconazole prophylaxis in neutropenic bone marrow transplant patients.
Topics: Amphotericin B; Bacterial Infections; Bone Marrow Transplantation; Candida; Candidiasis; Fluconazole | 1993 |
Antifungal susceptibility of Aspergillus species isolated from invasive oral infection in neutropenic patients with hematologic malignancies.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Aspergillosis; Aspergillus; D | 1999 |
Recognition and successful management in pulmonary aspergillosis in leukemia.
Topics: Adult; Aged; Amphotericin B; Aspergillosis; Female; Flucytosine; Humans; Leukemia; Lung Diseases, Fu | 1978 |
Hepatosplenic candidiasis: successful treatment with fluconazole.
Topics: Acute Disease; Adolescent; Adult; Amphotericin B; Candidiasis; Child; Child, Preschool; Fluconazole; | 1991 |
Preliminary results of treatment with itraconazole in patients with systemic fungal infections.
Topics: Acute Disease; Adult; Agranulocytosis; Antifungal Agents; Antineoplastic Agents; Drug Evaluation; Dr | 1990 |
Invasive pulmonary aspergillosis in acute leukemia. The contribution of CT to early diagnosis and aggressive management.
Topics: Acute Disease; Adult; Aged; Amphotericin B; Aspergillosis; Female; Flucytosine; Humans; Leukemia; Lu | 1987 |
Skin lesions associated with disseminated candidiasis.
Topics: Aged; Amphotericin B; Biopsy; Candida; Candidiasis; Candidiasis, Cutaneous; Child, Preschool; Female | 1974 |