flucytosine has been researched along with Kidney Diseases in 33 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Fungal bezoars are best treated with oral flucytosine, ureteral and renal irrigation with amphotericin and, occasionally, operation." | 4.76 | Evaluation and treatment of urinary candidiasis. ( Janosko, EO; McRoberts, JW, 1979) |
| "Two very low birth weight infants who developed renal candidiasis with pelvicalyceal fungal concretions were treated medically with Amphotericin B and 5 Fluorocytosine." | 3.68 | Renal stone formation following medical treatment of renal candidiasis. ( Andrews, W; Cramer, BC; Ozere, R, 1990) |
| "Miconazole is a parenterally administered agent for patients acutely ill with candidiasis and other mycotic infections." | 2.36 | Antifungal agents used in systemic mycoses. Activity and therapeutic use. ( Craven, PC; Graybill, JR, 1983) |
| "Amphotericin B has remained the most effective therapeutic preparation for most types of neurological fungal disease, although important roles for 5-fluorocytosine, miconazole, and, more recently, ketoconazole are being recognized." | 2.36 | Treatment of fungal infections of the central nervous system. ( Bell, WE, 1981) |
| "Invasive candidiasis is a serious pathogen of late-onset sepsis in very low birth weight infants." | 1.48 | Retrograde Ureteral Catheterization: A Possible New Treatment for Renal Fungal Balls in Very Low Birth Weight Infants. ( Chang, JH; Chen, CW; Chi, H; Hsu, CH; Lin, CC; Sheu, JC; Tsai, JD, 2018) |
| "We report a case of cryptococcal meningitis in a 31-year-old HIV-positive man which was successfully treated with amphotericin B lipid emulsion." | 1.29 | Successful treatment of resistant cryptococcal meningitis with amphotericin B lipid emulsion after nephrotoxicity with conventional intravenous amphotericin B. ( Appleyard, MN; Hartley, JP; Leake, HA, 1994) |
| "Treatment by surgical removal of the bezoars, open placement of nephrostomy tubes and intravenous antifungal therapy resulted in apparent complete recovery." | 1.27 | Anuria in a premature infant due to ureteropelvic fungal bezoars. ( Brish, M; Graif, M; Laufer, J; Reichman, B, 1986) |
| "Primary renal candidiasis is an uncommon disorder." | 1.26 | Gross hematuria: a rare manifestation of primary renal candidiasis. ( Bansal, S; Napodano, RJ, 1980) |
| " In three patients, accumulation of toxic levels of 5-FC was related to diminished renal function." | 1.26 | Bone marrow toxicity associated with 5-fluorocytosine therapy. ( Frame, PT; Kauffman, CA, 1977) |
| " Renal clearance of 5-FC was about 75% of the creatinine clearance and a corresponding modification of drug dosage should be made in patients with renal insufficiency." | 1.25 | Use of 5-fluorocytosine in patients with impaired renal function. ( Dawborn, JK; Page, MD; Schiavone, DJ, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (72.73) | 18.7374 |
| 1990's | 6 (18.18) | 18.2507 |
| 2000's | 1 (3.03) | 29.6817 |
| 2010's | 2 (6.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, CW | 1 |
| Hsu, CH | 1 |
| Sheu, JC | 1 |
| Chi, H | 1 |
| Chang, JH | 1 |
| Lin, CC | 1 |
| Tsai, JD | 1 |
| Marie, I | 1 |
| Cheriet, S | 1 |
| Assie, C | 1 |
| Etienne, M | 1 |
| Favennec, L | 1 |
| Biyikli, NK | 1 |
| Tugtepe, H | 1 |
| Akpinar, I | 1 |
| Alpay, H | 1 |
| Ozek, E | 1 |
| Graybill, JR | 1 |
| Craven, PC | 1 |
| Pappu, LD | 1 |
| Purohit, DM | 1 |
| Bradford, BF | 1 |
| Turner, WR | 1 |
| Levkoff, AH | 1 |
| Prat, O | 1 |
| Schurr, D | 1 |
| Pomeranz, A | 1 |
| Farkas, A | 1 |
| Drukker, A | 1 |
| Bell, WE | 1 |
| Napodano, RJ | 1 |
| Bansal, S | 1 |
| al-Rasheed, SA | 1 |
| Leake, HA | 1 |
| Appleyard, MN | 1 |
| Hartley, JP | 1 |
| Noone, P | 1 |
| Beale, DF | 1 |
| Pollock, SS | 1 |
| Perera, MR | 1 |
| Amirak, ID | 1 |
| Fernando, ON | 1 |
| Moorhead, JF | 1 |
| Demierre, G | 1 |
| Freedman, LR | 1 |
| Janosko, EO | 1 |
| McRoberts, JW | 1 |
| Kauffman, CA | 1 |
| Frame, PT | 1 |
| Medoff, G | 1 |
| Kobayashi, GS | 1 |
| Warshawsky, AB | 1 |
| Keiller, D | 1 |
| Gittes, RF | 1 |
| Heidemann, HT | 1 |
| Brune, KH | 1 |
| Sabra, R | 1 |
| Branch, RA | 1 |
| Matsumoto, AH | 1 |
| Dejter, SW | 1 |
| Barth, KH | 1 |
| Gibbons, MD | 1 |
| Cramer, BC | 1 |
| Ozere, R | 1 |
| Andrews, W | 1 |
| Ackerbauer, H | 1 |
| Meingassner, JG | 1 |
| Mieth, H | 1 |
| Heidemann, H | 1 |
| Davies, SP | 1 |
| Webb, WJ | 1 |
| Patou, G | 1 |
| Murray, WK | 1 |
| Denning, DW | 1 |
| Laufer, J | 1 |
| Reichman, B | 1 |
| Graif, M | 1 |
| Brish, M | 1 |
| Yang, DJ | 1 |
| Rankin, GO | 1 |
| Turner, RB | 1 |
| Donowitz, LG | 1 |
| Hendley, JO | 1 |
| Fransen, G | 1 |
| Van Camp, K | 1 |
| Utz, JP | 1 |
| Wise, GJ | 1 |
| Kozinn, PJ | 1 |
| Toni, E | 1 |
| Firkin, FC | 1 |
| Schönebeck, J | 1 |
| Polak, A | 1 |
| Fernex, M | 1 |
| Scholer, HJ | 1 |
| Dawborn, JK | 1 |
| Page, MD | 1 |
| Schiavone, DJ | 1 |
7 reviews available for flucytosine and Kidney Diseases
| Article | Year |
|---|---|
The longest use of liposomal amphotericin B and 5-fluorocytosine in neonatal renal candidiasis.
Topics: Acute Kidney Injury; Amphotericin B; Antifungal Agents; Candidiasis; Female; Flucytosine; Humans; In | 2004 |
Antifungal agents used in systemic mycoses. Activity and therapeutic use.
Topics: Amphotericin B; Antifungal Agents; Central Nervous System; Flucytosine; Humans; Imidazoles; Ketocona | 1983 |
Treatment of fungal infections of the central nervous system.
Topics: Amphotericin B; Antifungal Agents; Central Nervous System Diseases; Chemical Phenomena; Chemistry; F | 1981 |
The management of fungal obstructive uropathy in neonates and infants.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Flucytosine; Humans; Hydronephrosis; Infant; | 1994 |
Evaluation and treatment of urinary candidiasis.
Topics: Amphotericin B; Bezoars; Candidiasis; Flucytosine; Humans; Kidney Diseases; Urologic Diseases | 1979 |
Prevention of amphotericin B nephrotoxicity: the effect of salt loading and flucytosine.
Topics: Amphotericin B; Animals; Flucytosine; Humans; Kidney; Kidney Diseases; Sodium | 1988 |
Nephrotoxicity of antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Chemical Phenomena; Chemistry; Dermatomycoses; Flucytosine; Grise | 1985 |
26 other studies available for flucytosine and Kidney Diseases
| Article | Year |
|---|---|
Retrograde Ureteral Catheterization: A Possible New Treatment for Renal Fungal Balls in Very Low Birth Weight Infants.
Topics: Amphotericin B; Antifungal Agents; Anuria; Candidiasis; Caspofungin; Female; Flucytosine; Humans; In | 2018 |
Cryptococcosis in sarcoidosis.
Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcosis; Drug Therapy, Combination; Flucytosine; Hu | 2010 |
Primary renal candidiasis in two preterm neonates. Report of cases and review of literature on renal candidiasis in infancy.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Female; Flucytosine; Humans; Hydronephrosis; | 1984 |
Renal candidiasis in infancy--a case with fungus ball obstruction.
Topics: Amphotericin B; Candidiasis; Flucytosine; Humans; Infant, Newborn; Kidney; Kidney Diseases; Male; Ur | 1984 |
Gross hematuria: a rare manifestation of primary renal candidiasis.
Topics: Aged; Candidiasis; Diabetes Complications; Female; Flucytosine; Hematuria; Humans; Kidney Diseases | 1980 |
Successful treatment of resistant cryptococcal meningitis with amphotericin B lipid emulsion after nephrotoxicity with conventional intravenous amphotericin B.
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Drug Resistance, Microbial; Fat Emulsi | 1994 |
Systemic antifungal drugs.
Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidom | 1997 |
Monitoring aminoglycoside use in patients with severely impaired renal function.
Topics: Aminoglycosides; Carbenicillin; Cross Infection; Drug Interactions; Flucytosine; Humans; Kidney Dise | 1978 |
Experimental endocarditis: prophylaxis of Candida albicans infections by 5-fluorocytosine in rabbits.
Topics: Animals; Candida albicans; Candidiasis; Cytosine; Drug Resistance, Microbial; Embolism; Endocarditis | 1979 |
Drugs for the treatment of systemic fungal infections.
Topics: Amphotericin B; Clotrimazole; Drug Therapy, Combination; Flucytosine; Humans; Kidney Diseases; Menin | 1978 |
Bone marrow toxicity associated with 5-fluorocytosine therapy.
Topics: Adult; Aged; Bone Marrow Diseases; Cytosine; Female; Flucytosine; Humans; Kidney Diseases; Leukopeni | 1977 |
Amphotericin B: a second look.
Topics: Amphotericin B; Animals; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Fl | 1977 |
Bilateral renal aspergillosis.
Topics: Adult; Amphotericin B; Aspergillosis; Drug Synergism; Flucytosine; Humans; Kidney Diseases; Male; Ri | 1975 |
Acute and chronic effects of flucytosine on amphotericin B nephrotoxicity in rats.
Topics: Amphotericin B; Animals; Disease Models, Animal; Drug Combinations; Drug Interactions; Flucytosine; | 1992 |
Percutaneous nephrostomy drainage in the management of neonatal anuria secondary to renal candidiasis.
Topics: Amphotericin B; Anuria; Bezoars; Candidiasis; Drainage; Flucytosine; Humans; Infant, Newborn; Infant | 1990 |
Renal stone formation following medical treatment of renal candidiasis.
Topics: Amphotericin B; Candidiasis; Female; Flucytosine; Humans; Infant; Infant, Newborn; Infant, Premature | 1990 |
[Experimental renal infection with Aspergillus fumigatus in mice: a chemotherapeutic model of an organic mycosis].
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Disease Models, An | 1985 |
Renal aspergilloma--a case illustrating the problems of medical therapy.
Topics: Amphotericin B; Aspergillosis; Female; Flucytosine; Humans; Ketoconazole; Kidney Diseases; Middle Ag | 1987 |
Anuria in a premature infant due to ureteropelvic fungal bezoars.
Topics: Amphotericin B; Anuria; Bezoars; Candidiasis; Female; Flucytosine; Follow-Up Studies; Humans; Infant | 1986 |
Consequences of candidemia for pediatric patients.
Topics: Adolescent; Amphotericin B; Blood; Blood Urea Nitrogen; Candidiasis; Child; Child, Preschool; Creati | 1985 |
[Renal and urothelial candidiasis].
Topics: Adult; Antifungal Agents; Candidiasis; Female; Flucytosine; Humans; Kidney Diseases; Male; Miconazol | 1974 |
Current and future chemotherapy of central nervous system fungal infections.
Topics: Administration, Oral; Amphotericin B; Arrhythmias, Cardiac; Brain Diseases; Cytosine; Flucytosine; G | 1974 |
Yeast in the urine.
Topics: Amphotericin B; Candida albicans; Candidiasis; Cystitis; Female; Flucytosine; Humans; Kidney Disease | 1973 |
Therapy of deep-seated fungal infections with 5-fluorocytosine.
Topics: Adult; Aged; Amphotericin B; Anterior Chamber; Aspergillosis; Aspergillus fumigatus; Candida albican | 1974 |
Pharmacokinetic studies on the oral antimycotic agent 5-fluorocytosine in individuals with normal and impaired kidney function.
Topics: Adult; Aged; Alkaline Phosphatase; Antifungal Agents; Blood Platelets; Body Weight; Creatinine; Cyto | 1973 |
Use of 5-fluorocytosine in patients with impaired renal function.
Topics: Antifungal Agents; Creatinine; Cytosine; Flucytosine; Half-Life; Humans; Kidney; Kidney Diseases | 1973 |