flucytosine has been researched along with Intracranial Hypertension in 12 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Intracranial Hypertension: Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cryptococcal meningitis is a severe fungal infection that occurs primarily in the setting of advanced immunodeficiency and remains a major cause of HIV-related deaths worldwide." | 2.58 | Treatment for HIV-associated cryptococcal meningitis. ( Eshun-Wilson, I; Ford, N; Jarvis, JN; Li, T; Rouse, B; Shapiro, AE; Tenforde, MW, 2018) |
| " The optimal dosing of AmB remains unclear." | 2.44 | Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings. ( Dedicoat, M; Dlamini, S; Paul, N; Sloan, D, 2008) |
| "Cryptococcal meningitis is a difficult disease to treat and requires biochemical and haematological monitoring to detect the common adverse effects of treatment." | 2.39 | The management of cryptococcal meningitis in Papua New Guinea. ( Seaton, RA, 1996) |
| "Cryptococcal meningitis is a fungal infection that is most commonly thought of as an opportunistic infection affecting immunocompromised patients, classically patients with Human Immunodeficiency (HIV) infection." | 1.56 | Cryptococcal meningitis in an immunocompetent patient. ( Lacy, AJ; Murphy, LS; Shah, KS; Smith, AT, 2020) |
| "Triple antifungal agents combined with VPS could effectively reduce ICP, had faster rate of clearance of C." | 1.56 | Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure. ( Deng, X; Gan, Q; Jiang, Y; Li, M; Liu, J; Peng, F; Wang, Y; Xu, X, 2020) |
| "Cryptococcal meningitis is the most common life-threatening fungal infection and is associated with high mortality in children." | 1.36 | The role of an Ommaya reservoir in the management of children with cryptococcal meningitis. ( Gao, F; Jiang, PF; Shen, SX; Shui, QX; Xia, ZZ; Yu, HM; Zhou, BL, 2010) |
| "Two patients with HIV/AIDS (CD4 counts of 8 and 81 cells/mm(3)) presented with altered mental status, visual changes, florid cryptococcal meningitis, and elevated ICP (>500 mm CSF) without evidence of hydrocephalus on computed tomography scan." | 1.33 | The use of ventriculoperitoneal shunts for uncontrollable intracranial hypertension without ventriculomegally secondary to HIV-associated cryptococcal meningitis. ( McGirt, MJ; Rigamonti, D; Williams, MA; Woodworth, GF, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Temfack, E | 1 |
| Boyer-Chammard, T | 1 |
| Lawrence, D | 1 |
| Delliere, S | 1 |
| Loyse, A | 1 |
| Lanternier, F | 1 |
| Alanio, A | 1 |
| Lortholary, O | 1 |
| Murphy, LS | 1 |
| Lacy, AJ | 1 |
| Smith, AT | 1 |
| Shah, KS | 1 |
| Li, M | 1 |
| Liu, J | 1 |
| Deng, X | 1 |
| Gan, Q | 1 |
| Wang, Y | 1 |
| Xu, X | 1 |
| Jiang, Y | 1 |
| Peng, F | 1 |
| Tenforde, MW | 1 |
| Shapiro, AE | 1 |
| Rouse, B | 1 |
| Jarvis, JN | 1 |
| Li, T | 1 |
| Eshun-Wilson, I | 1 |
| Ford, N | 1 |
| Espino Barros Palau, A | 1 |
| Morgan, ML | 1 |
| Foroozan, R | 1 |
| Lee, AG | 1 |
| Sloan, D | 1 |
| Dlamini, S | 1 |
| Paul, N | 1 |
| Dedicoat, M | 1 |
| Soares, BM | 1 |
| Santos, DA | 1 |
| Kohler, LM | 1 |
| da Costa César, G | 1 |
| de Carvalho, IR | 1 |
| dos Anjos Martins, M | 1 |
| Cisalpino, PS | 1 |
| Jiang, PF | 1 |
| Yu, HM | 1 |
| Zhou, BL | 1 |
| Gao, F | 1 |
| Shen, SX | 1 |
| Xia, ZZ | 1 |
| Shui, QX | 1 |
| Liao, CH | 1 |
| Chi, CY | 1 |
| Wang, YJ | 1 |
| Tseng, SW | 1 |
| Chou, CH | 1 |
| Ho, CM | 1 |
| Lin, PC | 1 |
| Ho, MW | 1 |
| Wang, JH | 1 |
| Woodworth, GF | 1 |
| McGirt, MJ | 1 |
| Williams, MA | 1 |
| Rigamonti, D | 1 |
| Seaton, RA | 1 |
| Graybill, JR | 1 |
| Sobel, J | 1 |
| Saag, M | 1 |
| van Der Horst, C | 1 |
| Powderly, W | 1 |
| Cloud, G | 1 |
| Riser, L | 1 |
| Hamill, R | 1 |
| Dismukes, W | 1 |
4 reviews available for flucytosine and Intracranial Hypertension
| Article | Year |
|---|---|
New Insights Into Cryptococcus Spp. Biology and Cryptococcal Meningitis.
Topics: Amphotericin B; Antifungal Agents; Antiretroviral Therapy, Highly Active; Cryptococcus; Drug Therapy | 2019 |
Treatment for HIV-associated cryptococcal meningitis.
Topics: Acetazolamide; Acute Disease; Adult; Amphotericin B; Antifungal Agents; Developing Countries; Drug A | 2018 |
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings.
Topics: Acetazolamide; Acute Disease; Adult; Amphotericin B; Antifungal Agents; Antihypertensive Agents; Dev | 2008 |
The management of cryptococcal meningitis in Papua New Guinea.
Topics: Amphotericin B; Anti-Inflammatory Agents; Antifungal Agents; Cause of Death; Drug Combinations; Drug | 1996 |
1 trial available for flucytosine and Intracranial Hypertension
| Article | Year |
|---|---|
Diagnosis and management of increased intracranial pressure in patients with AIDS and cryptococcal meningitis. The NIAID Mycoses Study Group and AIDS Cooperative Treatment Groups.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cerebrospinal Fluid; Flucy | 2000 |
7 other studies available for flucytosine and Intracranial Hypertension
| Article | Year |
|---|---|
Cryptococcal meningitis in an immunocompetent patient.
Topics: Adult; Amphotericin B; Antifungal Agents; Culture Techniques; Delayed Diagnosis; Fluconazole; Flucyt | 2020 |
Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure.
Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Drug Therapy, Combination; Female | 2020 |
Neuro-ophthalmic presentations and treatment of Cryptococcal meningitis-related increased intracranial pressure.
Topics: Amphotericin B; Antibodies, Fungal; Antifungal Agents; Antigens, Fungal; Cryptococcosis; Cryptococcu | 2014 |
Cerebral infection caused by Cryptococcus gattii: a case report and antifungal susceptibility testing.
Topics: Amphotericin B; Antifungal Agents; Child; Cryptococcus; Drug Resistance, Multiple, Fungal; Drug Syne | 2008 |
The role of an Ommaya reservoir in the management of children with cryptococcal meningitis.
Topics: Amphotericin B; Antifungal Agents; Child; Cryptococcus neoformans; Drug Delivery Systems; Female; Fl | 2010 |
Different presentations and outcomes between HIV-infected and HIV-uninfected patients with Cryptococcal meningitis.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antigens, Fun | 2012 |
The use of ventriculoperitoneal shunts for uncontrollable intracranial hypertension without ventriculomegally secondary to HIV-associated cryptococcal meningitis.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Dr | 2005 |