flucytosine has been researched along with Infective Endocarditis in 44 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the efficacies of fluconazole (Flu), amphotericin B (AmB), and 5-fluorocytosine (5FC) monotherapies with the combination of Flu plus 5FC and Flu plus AmB in a rabbit model of Candida albicans endocarditis, endophthalmitis, and pyelonephritis." | 7.70 | Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d ( Drusano, GL; Liu, QF; Liu, W; Louie, A; Mayers, M; Miller, DA; Miller, MH; Sucke, AC, 1999) |
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 7.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| "A 7-year-old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae and was treated successfully with orally administered antifungal agent, namely 5-fluorocytosine (5-FC)." | 7.65 | Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine. ( Friedman, A; Hashman, N; Merzbach, D; Naveh, Y, 1975) |
| "We compared the efficacies of fluconazole (Flu), amphotericin B (AmB), and 5-fluorocytosine (5FC) monotherapies with the combination of Flu plus 5FC and Flu plus AmB in a rabbit model of Candida albicans endocarditis, endophthalmitis, and pyelonephritis." | 3.70 | Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d ( Drusano, GL; Liu, QF; Liu, W; Louie, A; Mayers, M; Miller, DA; Miller, MH; Sucke, AC, 1999) |
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 3.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| " Serum and cultural data as well as the excellent response to treatment with 5-flucytosine seems to confirm the diagnosis of candida infection." | 3.67 | [A case of mycotic endocarditis. Clinical, diagnostic and therapeutic considerations]. ( Campisi, E; Cecchi, F; Faggi, E; Lampronti, V; Niosi, L, 1985) |
| "A 7-year-old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae and was treated successfully with orally administered antifungal agent, namely 5-fluorocytosine (5-FC)." | 3.65 | Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine. ( Friedman, A; Hashman, N; Merzbach, D; Naveh, Y, 1975) |
| " The proper duration and dosage and the combination of antifungal drugs have not been clearly defined." | 2.38 | [Primary Aspergillus endocarditis. Apropos of a case and review of the international literature]. ( Cajot, MA; Gosselin, B; Goullard, L; Koussa, A; Marquette, F; Pol, A; Roux, JP; Soots, G; Warembourg, H, 1992) |
| "Endocarditis is an uncommon complication of disseminated candidiasis among premature infants, but has been recently reported to be almost uniformly fatal." | 1.28 | Successful medical treatment of Candida parapsilosis endocarditis in a premature infant. ( Faix, RG; Feick, HJ; Frommelt, P; Snider, AR, 1990) |
| "Aspergillus endocarditis is associated with a very high mortality." | 1.27 | Successful treatment of post-mitral valve annuloplasty Aspergillus flavus endocarditis. ( Bonchek, LI; Rytel, MW; Shimshak, T; Wagner, DK; Werner, PH, 1985) |
| "Successful treatment of fungal endocarditis is being described with increasing frequency." | 1.26 | Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported. ( Galgiani, JN; Stevens, DA, 1977) |
| "In addition to arterial embolism, occult mycotic aneurysms were found by arteriography." | 1.26 | Treatment of Candida endocarditis and arteritis. ( Cerruti, MM; Friedman, SA; Gladstone, JL; Jomain, SL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (65.91) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 5 (11.36) | 29.6817 |
| 2010's | 2 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guragai, N | 1 |
| Rampal, U | 1 |
| Vasudev, R | 1 |
| Shah, D | 1 |
| Patel, H | 1 |
| Salamera, J | 1 |
| Pullatt, R | 1 |
| Shamoon, F | 1 |
| Chiron, LM | 1 |
| Pihet, M | 1 |
| Rouleau, F | 1 |
| de Gentile, L | 1 |
| Bouchara, JP | 1 |
| Chabasse, D | 1 |
| Pai, MP | 2 |
| Bouraoui, H | 1 |
| Mahdhaoui, A | 1 |
| Zaaraoui, J | 1 |
| Mejdoub, M | 1 |
| Ernez-Hajri, S | 1 |
| Jeridi, G | 1 |
| Ammar, H | 1 |
| Wertz, KK | 1 |
| Pretzlaff, RK | 1 |
| Samples, ML | 1 |
| Mercier, RC | 1 |
| Spilde, MN | 1 |
| Samelson, LE | 1 |
| Lerner, SA | 1 |
| Resnekov, L | 1 |
| Anagnostopoulos, C | 1 |
| Vishniavsky, N | 1 |
| Sagar, KB | 1 |
| Markowitz, SM | 1 |
| Miyazono, K | 1 |
| Yoshida, M | 1 |
| Kitagawa, S | 1 |
| Tsuboyama, A | 1 |
| Sakamoto, S | 1 |
| Miura, Y | 1 |
| Shina, A | 1 |
| Darwazah, A | 1 |
| Berg, G | 1 |
| Faris, B | 1 |
| Louie, A | 1 |
| Liu, W | 1 |
| Miller, DA | 1 |
| Sucke, AC | 1 |
| Liu, QF | 1 |
| Drusano, GL | 1 |
| Mayers, M | 1 |
| Miller, MH | 1 |
| Jones, JM | 1 |
| Sarsam, MA | 1 |
| Clarke, MA | 1 |
| Hedderwick, SA | 1 |
| Sande, MA | 1 |
| Bowman, CR | 1 |
| Calderone, RA | 1 |
| Demierre, G | 1 |
| Freedman, LR | 1 |
| Martin, E | 1 |
| Pancoast, SJ | 1 |
| Neu, HC | 1 |
| Wain, W | 1 |
| Ahmed, M | 1 |
| Thompson, R | 1 |
| Yacoub, M | 1 |
| Drouhet, E | 1 |
| Dupont, B | 1 |
| Mayrer, AR | 1 |
| Brown, A | 1 |
| Weintraub, RA | 1 |
| Ragni, M | 1 |
| Postic, B | 1 |
| Galgiani, JN | 1 |
| Stevens, DA | 1 |
| Rotheram, EB | 1 |
| Magovern, GJ | 1 |
| Gladstone, JL | 1 |
| Friedman, SA | 1 |
| Cerruti, MM | 1 |
| Jomain, SL | 1 |
| Sharpe, DN | 1 |
| Singh, BN | 1 |
| Cornere, BM | 1 |
| Allwood, GK | 1 |
| Premsingh, N | 1 |
| Kapila, R | 1 |
| Tecson, F | 1 |
| Smith, LG | 1 |
| Louria, DB | 1 |
| Darrell, JH | 1 |
| Naveh, Y | 1 |
| Friedman, A | 1 |
| Merzbach, D | 1 |
| Hashman, N | 1 |
| Rubinstein, E | 1 |
| Noriega, ER | 1 |
| Simberkoff, MS | 1 |
| Holzman, R | 1 |
| Rahal, JJ | 1 |
| Stone, DL | 1 |
| Roux, JP | 1 |
| Koussa, A | 1 |
| Cajot, MA | 1 |
| Marquette, F | 1 |
| Goullard, L | 1 |
| Gosselin, B | 1 |
| Pol, A | 1 |
| Warembourg, H | 1 |
| Soots, G | 1 |
| Zenker, PN | 1 |
| Rosenberg, EM | 1 |
| Van Dyke, RB | 1 |
| Rabalais, GP | 1 |
| Daum, RS | 1 |
| Sánchez, PJ | 1 |
| Siegel, JD | 1 |
| Fishbein, J | 1 |
| Kasugai, H | 1 |
| Watanabe, Y | 1 |
| Nakamura, T | 1 |
| Sotozono, K | 1 |
| Asahi, Y | 1 |
| Murayama, M | 1 |
| Sugai, J | 1 |
| Okada, T | 1 |
| Kawada, T | 1 |
| Abe, M | 1 |
| Bogner, JR | 1 |
| Lüftl, S | 1 |
| Middeke, M | 1 |
| Spengel, F | 1 |
| Faix, RG | 1 |
| Feick, HJ | 1 |
| Frommelt, P | 1 |
| Snider, AR | 1 |
| Longman, LP | 1 |
| Martin, MV | 1 |
| Wagner, DK | 1 |
| Werner, PH | 1 |
| Bonchek, LI | 1 |
| Shimshak, T | 1 |
| Rytel, MW | 1 |
| Lampronti, V | 1 |
| Niosi, L | 1 |
| Campisi, E | 1 |
| Faggi, E | 1 |
| Cecchi, F | 1 |
| Acar, J | 1 |
| Cabrol, C | 1 |
| Jallut, H | 1 |
| Frottier, J | 1 |
| Duron, F | 1 |
| Bastin, R | 1 |
| Logan, RL | 1 |
| Goldberg, MJ | 1 |
| Harford, CG | 1 |
| Montague, NT | 1 |
| Sugg, WL | 1 |
| Carrizosa, J | 1 |
| Levison, ME | 1 |
| Lawrence, T | 1 |
| Kaye, D | 1 |
| Hoeprich, PD | 1 |
| Ingraham, JL | 1 |
| Kleker, E | 1 |
| Winship, MJ | 1 |
| Harris, PD | 1 |
| Yeoh, CB | 1 |
| Breault, J | 1 |
| Meltzer, J | 1 |
| Katz, S | 1 |
| Record, CO | 1 |
| Skinner, JM | 1 |
| Sleight, P | 1 |
| Speller, DC | 1 |
3 reviews available for flucytosine and Infective Endocarditis
| Article | Year |
|---|---|
Candida endocarditis in two patients.
Topics: Adolescent; Amphotericin B; Aortic Valve; Candidiasis; Drug Therapy, Combination; Endocarditis; Fluc | 1976 |
[Primary Aspergillus endocarditis. Apropos of a case and review of the international literature].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Combined Modality Therapy; | 1992 |
Candida endocarditis: successful medical management in three preterm infants and review of the literature.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Endocarditis; Female; Flucytosine; Humans; I | 1991 |
41 other studies available for flucytosine and Infective Endocarditis
| Article | Year |
|---|---|
Isolated Pulmonary Valve Fungal Endocarditis with Candida parapsilosis: Management Considerations of a Rare Case.
Topics: Administration, Intravenous; Adult; Amphotericin B; Antifungal Agents; Candida parapsilosis; Candidi | 2017 |
[Comment on this case report].
Topics: Adult; Amphotericin B; Antifungal Agents; Buprenorphine; Candidiasis; Endocarditis; Endophthalmitis; | 2012 |
Antifungal combinations against simulated Candida albicans endocardial vegetations.
Topics: Amphotericin B; Antifungal Agents; Biofilms; Candida albicans; Drug Combinations; Echinocandins; End | 2009 |
[Candida albicans prosthetic valve endocarditis. Two cases].
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Drug Therapy, Combination; Endocar | 2002 |
Caspofungin in a pediatric patient with persistent candidemia.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Child, Preschool; Drug Therapy, Combina | 2004 |
Activities and ultrastructural effects of antifungal combinations against simulated Candida endocardial vegetations.
Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis; Dru | 2008 |
Relapse of Candida parapsilosis endocarditis after long-term suppression with flucytosin: retreatment with valve replacement and ketoconazole.
Topics: Adult; Amphotericin B; Candidiasis; Cytosine; Drug Therapy, Combination; Endocarditis; Female; Flucy | 1980 |
Aspergillus fumigatus endocarditis on a normal heart valve.
Topics: Aged; Amphotericin B; Aspergillosis; Aspergillus fumigatus; Bioprosthesis; Drug Therapy, Combination | 1983 |
[Pulmonary aspergillosis associated with endocarditis and cerebral embolism in a case of acute myeloblastic leukemia].
Topics: Amphotericin B; Aspergillosis; Aspergillus fumigatus; Endocarditis; Flucytosine; Humans; Intracrania | 1984 |
Candida parapsilosis: an unusual organism causing prosthetic heart valve infective endocarditis.
Topics: Aged; Amphotericin B; Antifungal Agents; Aortic Valve; C-Reactive Protein; Candida; Candidiasis; Dru | 1999 |
Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d
Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Creatinine; Endocarditis; | 1999 |
Candida parapsilosis: two cases of endocarditis in association with the Toronto stentless porcine valve.
Topics: Aged; Aged, 80 and over; Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis; Endocardi | 2002 |
Experimental Candida albicans endocarditis: characterization of the disease and response to therapy.
Topics: Agglutinins; Amphotericin B; Animals; Antibodies, Fungal; Aortic Valve; Candida albicans; Candidiasi | 1977 |
Experimental endocarditis: prophylaxis of Candida albicans infections by 5-fluorocytosine in rabbits.
Topics: Animals; Candida albicans; Candidiasis; Cytosine; Drug Resistance, Microbial; Embolism; Endocarditis | 1979 |
Candida parapsilosis endocarditis: medical and surgical cure.
Topics: Adult; Amphotericin B; Aortic Valve; Candidiasis; Endocarditis; Flucytosine; Humans; Male | 1979 |
The role of chemotherapy in the management of fungal endocaridits following homograft valve replacement.
Topics: Amphotericin B; Endocarditis; Flucytosine; Heart Valves; Humans; Mycoses; Postoperative Complication | 1979 |
[Iatrogenic mycoses with deep visceral localization caused by opportunistic fungi].
Topics: Amphotericin B; Candida; Candidiasis; Cryptococcosis; Dermatomycoses; Endocarditis; Flucytosine; Hum | 1979 |
Successful medical therapy for endocarditis due to Candida parapsilosis. A clinical and epidemiologic study.
Topics: Adult; Amphotericin B; Candida; Candidiasis; Endocarditis; Flucytosine; Humans; Male | 1978 |
Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported.
Topics: Adult; Amphotericin B; Aortic Valve Stenosis; Candidiasis; Cytosine; Endocarditis; Flucytosine; Hear | 1977 |
Two-year cure of Candida infection of prosthetic mitral valve.
Topics: Amphotericin B; Atrial Fibrillation; Candidiasis; Digoxin; Embolism; Endocarditis; Female; Flucytosi | 1977 |
Treatment of Candida endocarditis and arteritis.
Topics: Adult; Amphotericin B; Aneurysm, Infected; Aortography; Arterial Occlusive Diseases; Arteritis; Cand | 1976 |
Torulopsis glabrata endocarditis complicating aortic homograft valve treated with 5-fluorocytosine: case report with discussion of antifungal chemotherapy.
Topics: Amphotericin B; Aortic Valve; Aortic Valve Stenosis; Autopsy; Candida; Candidiasis; Cytosine; Endoca | 1975 |
Letter: Candida endocarditis.
Topics: Amphotericin B; Candidiasis; Endocarditis; Flucytosine; Humans | 1975 |
Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine.
Topics: Administration, Oral; Antifungal Agents; Aortic Valve Insufficiency; Candidiasis; Child; Cytosine; E | 1975 |
Fungal endocarditis: analysis of 24 cases and review of the literature.
Topics: Adolescent; Adult; Aged; Amphotericin B; Aspergillosis; Candida; Candidiasis; Cardiac Surgical Proce | 1975 |
Candida endocarditis treated with a combination of antifungal chemotherapy and aortic valve replacement.
Topics: Amphotericin B; Aortic Valve; Candidiasis; Endocarditis; Flucytosine; Heart Valve Prosthesis; Humans | 1975 |
Successful medical treatment of presumed Candida endocarditis in critically ill infants.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Endocarditis; Female; Flucytosine; Humans; I | 1991 |
[A successfully treated case of infective endocarditis due to Candida tropicalis].
Topics: Adult; Amphotericin B; Candida; Candidiasis; Drug Therapy, Combination; Endocarditis; Flucytosine; H | 1990 |
[Successful drug therapy in Aspergillus endocarditis].
Topics: Aged; Amphotericin B; Amputation, Surgical; Aortic Valve; Aspergillosis; Aspergillus fumigatus; Comb | 1990 |
Successful medical treatment of Candida parapsilosis endocarditis in a premature infant.
Topics: Amphotericin B; Candidiasis; Endocarditis; Flucytosine; Humans; Infant, Newborn; Infant, Premature, | 1990 |
A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Endocarditis; Fluc | 1987 |
Successful treatment of post-mitral valve annuloplasty Aspergillus flavus endocarditis.
Topics: Amphotericin B; Aspergillosis; Aspergillus flavus; Combined Modality Therapy; Cytosine; Endocarditis | 1985 |
[A case of mycotic endocarditis. Clinical, diagnostic and therapeutic considerations].
Topics: Adolescent; Anorexia; Benzodiazepines; Candidiasis; Depression; Dibenzocycloheptenes; Echocardiograp | 1985 |
[Candida endocarditis in mitral prosthesis (apropos of a case cured by a second operation)].
Topics: Amphotericin B; Candida; Candidiasis; Endocarditis; Female; Flucytosine; Heart Valve Prosthesis; Hum | 1973 |
C. albicans resistance to 5-fluorocytosine.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Cytosine; Drug Resistance, Microbial; Endocarditis | 1972 |
Postoperative fungal endocarditis. Fungemia, embolism, and therapy.
Topics: Aged; Amphotericin B; Aortic Valve; Aspergillus; Blood; Candida; Candida albicans; Cryptococcus; Emb | 1974 |
Candida endocarditis with femoral emboli. Treatment with surgery and 5-fluorocytosine.
Topics: Antifungal Agents; Aortic Valve; Candidiasis; Cytosine; Embolism; Endocarditis; Femoral Artery; Fluc | 1974 |
Cure of Aspergillus ustus endocarditis on a prosthetic valve.
Topics: Amphotericin B; Aortic Valve; Aspergillosis; Aspergillus; Drug Therapy, Combination; Endocarditis; F | 1974 |
Development of resistance to 5-fluorocytosine in Candida parapsilosis during therapy.
Topics: Adult; Aminohydrolases; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Cell-Free System; C | 1974 |
Fungal endocarditis secondary to drug addiction. Recent concepts in diagnosis and therapy.
Topics: Adult; Amphotericin B; Aortic Valve Insufficiency; Benzene Derivatives; Candidiasis; Endocarditis; F | 1972 |
Candida endocarditis treated with 5-fluorocytosine.
Topics: Aged; Bone Marrow Diseases; Candidiasis; Endocarditis; Female; Flucytosine; Heart Valve Prosthesis; | 1971 |