Page last updated: 2024-10-27

flucytosine and Hematologic Diseases

flucytosine has been researched along with Hematologic Diseases in 6 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
"Therapeutic effectiveness of 5-fluorocytosine (5-FC), amphotericin B (Am B) and both in combined administration were retrospectively assessed and compared with one another in 28 patients with cryptococcal meningitis."9.04Comparison between 5-fluorocytosine, amphotericin B and the combined administration of these agents in the therapeutic effectiveness for cryptococcal meningitis. ( Ikemoto, H; Jimbow, T; Tejima, Y, 1978)
"In a prospective study from May 1971 to November 1973, 20 consecutive patients with a diagnosis of disseminated cryptococcosis were treated for six weeks with a combination of amphotericin B (20 mg daily) intravenously and flucytosine (150 mg/kg daily) orally."7.65Therapy of cryptococcosis with a combination of flucytosine and amphotericin B. ( Duma, RJ; Garriques, IL; Mandell, GL; McGehee, RF; Sande, MA; Shadomy, S; Utz, JP; Warner, JF, 1975)
"Therapeutic effectiveness of 5-fluorocytosine (5-FC), amphotericin B (Am B) and both in combined administration were retrospectively assessed and compared with one another in 28 patients with cryptococcal meningitis."5.04Comparison between 5-fluorocytosine, amphotericin B and the combined administration of these agents in the therapeutic effectiveness for cryptococcal meningitis. ( Ikemoto, H; Jimbow, T; Tejima, Y, 1978)
"In a prospective study from May 1971 to November 1973, 20 consecutive patients with a diagnosis of disseminated cryptococcosis were treated for six weeks with a combination of amphotericin B (20 mg daily) intravenously and flucytosine (150 mg/kg daily) orally."3.65Therapy of cryptococcosis with a combination of flucytosine and amphotericin B. ( Duma, RJ; Garriques, IL; Mandell, GL; McGehee, RF; Sande, MA; Shadomy, S; Utz, JP; Warner, JF, 1975)
"Another patient with acute myelogenous leukemia developed a huge brain abscess with histopathologic findings suspicious of mucormycosis."1.35Current approaches to management of cerebral fungal infection in pediatric patients with hematologic disorders. ( Ichikawa, M; Kaneda, M; Kobayashi, R; Nakagawa, A; Sato, T; Suzuki, D, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sato, T1
Kaneda, M1
Ichikawa, M1
Suzuki, D1
Nakagawa, A1
Kobayashi, R1
Kostiala, AA1
Kostiala, I1
Berenguer Berenguer, J1
Glasmacher, A1
Just-NĂ¼bling, G1
Molitor, E1
Jimbow, T1
Tejima, Y1
Ikemoto, H1
Utz, JP1
Garriques, IL1
Sande, MA1
Warner, JF1
Mandell, GL1
McGehee, RF1
Duma, RJ1
Shadomy, S1

Reviews

2 reviews available for flucytosine and Hematologic Diseases

ArticleYear
[Commonly used antifungal agents in the treatment of systemic mycoses].
    Revista clinica espanola, 1995, Volume: 195 Suppl 3

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Clinical Trials as Top

1995
[Therapy of invasive mycoses in neutropenic patients with hematologic system diseases].
    Deutsche medizinische Wochenschrift (1946), 1998, Feb-13, Volume: 123, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis; Chemistry, Pharmaceutical; Fluconazol

1998

Trials

1 trial available for flucytosine and Hematologic Diseases

ArticleYear
Comparison between 5-fluorocytosine, amphotericin B and the combined administration of these agents in the therapeutic effectiveness for cryptococcal meningitis.
    Chemotherapy, 1978, Volume: 24, Issue:6

    Topics: Adult; Aged; Amphotericin B; Clinical Trials as Topic; Cryptococcosis; Cytosine; Drug Administration

1978

Other Studies

3 other studies available for flucytosine and Hematologic Diseases

ArticleYear
Current approaches to management of cerebral fungal infection in pediatric patients with hematologic disorders.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Aspergillosis; Central Nervous

2008
Susceptibility of fungi in mouthrinse specimens from patients with haematological malignancies.
    Journal of medical microbiology, 1984, Volume: 18, Issue:2

    Topics: Antifungal Agents; Candida; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Flucyto

1984
Therapy of cryptococcosis with a combination of flucytosine and amphotericin B.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:4

    Topics: Adult; Aged; Amphotericin B; Cryptococcosis; Cytosine; Drug Therapy, Combination; Female; Flucytosin

1975