flucytosine has been researched along with Fungemia in 43 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Fungemia: The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These events have lead to the development of new antifungal agents, and amphotericin B no longer is the standard therapy for a variety of invasive mycoses." | 4.80 | Therapy of invasive fungal infections. ( de Pauw, BE; Kullberg, BJ, 1999) |
| " Therapeutic usage of amphotericin B, the agent of choice for serious Candida infection, is reviewed, along with usage of 5-flucytosine and fluconazole." | 4.78 | Pathogenesis and management of Candida infection syndromes in non-neutropenic patients. ( Solomkin, JS, 1993) |
| "The in vitro activity of amphotericin B, flucytosine and fluconazole against 95 yeasts causing fungemia in a single institution over the last eight years was determined by a broth macromethod recommended by the National Committee for Clinical Laboratory Standards." | 3.69 | In vitro activity of amphotericin B, flucytosine and fluconazole against yeasts causing bloodstream infections. ( Berenguer, J; Bouza, E; Fernández-Baca, V; Sánchez, R, 1995) |
| "We performed antifungal susceptibility tests with cilofungin (LY121019), amphotericin B, and flucytosine against 38 strains of yeasts from patients with esophagitis or fungemia either before, during, or after treatment with cilofungin." | 3.69 | Comparative analysis of three antifungal susceptibility test methods against prospectively collected Candida species. ( Cook, RA; Crane, LR; Galgiani, JN; Gallis, HA; Pappas, PG; Pottage, JC; Villareal, KM; Wenzel, RP, 1994) |
| "Infections with fluconazole-resistant Candida albicans isolate have rarely been described in clinical settings other than oropharyngeal candidiasis in patients with late-stage AIDS." | 3.69 | Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia. ( Dix, S; Falconer, DJ; Geller, R; Gilmore, C; Nolte, FS; Parkinson, T; Williams, J; Wingard, JR, 1997) |
| "Presentation with pleural effusion is rare in cryptococcal disease; in fact, only 4 cases of pleural effusion as the initial clinical presentation in cryptococcosis have been reported in English-language literature to date." | 2.52 | Pleural effusion as the initial clinical presentation in disseminated cryptococcosis and fungaemia: an unusual manifestation and a literature review. ( Chen, D; Chen, M; Dai, C; Huang, X; Li, Y; Wang, L; Wang, X; Xu, X; Yang, L; Yao, D; Yu, C; Yu, X, 2015) |
| " This article reviews recent pertinent data with regard to dosing guidelines, efficacy, and toxicities of available systemic antifungal agents in the newborn." | 2.42 | Antifungal pharmacotherapy for neonatal candidiasis. ( Bliss, JM; Gigliotti, F; Wellington, M, 2003) |
| "Cryptococcal meningitis is a fungal infection that is most commonly thought of as an opportunistic infection affecting immunocompromised patients, classically patients with Human Immunodeficiency (HIV) infection." | 1.56 | Cryptococcal meningitis in an immunocompetent patient. ( Lacy, AJ; Murphy, LS; Shah, KS; Smith, AT, 2020) |
| "Fluconazole resistance was detected in one isolate of C." | 1.33 | Epidemiology of candidemia in a Turkish tertiary care hospital. ( Bakir, M; Barton, R; Cerikcioglu, N; Yagci, A, 2006) |
| "Yeast fungemia has increased markedly in the last few years." | 1.30 | [A multicenter study on fungemia caused by yeasts in Spain (April-June, 1997). A Work Group to Study Fungemia)]. ( Cuenca-Estrella, M; Rodríguez-Tudela, JL, 1999) |
| "Brain abscess is a rare complication of candidemia but may be expected to become more common as venous catheter-related fungemia is encountered more frequently." | 1.29 | Candidal brain abscess associated with vascular invasion: a devastating complication of vascular catheter-related candidemia. ( Blatter, DD; Burgert, SJ; Burke, JP; Classen, DC, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.65) | 18.7374 |
| 1990's | 14 (32.56) | 18.2507 |
| 2000's | 17 (39.53) | 29.6817 |
| 2010's | 9 (20.93) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Seifert, H | 1 |
| Aurbach, U | 1 |
| Stefanik, D | 1 |
| Cornely, O | 1 |
| Fritsche, TR | 1 |
| Rhomberg, PR | 1 |
| Sader, HS | 1 |
| Jones, RN | 2 |
| Gomez-Lopez, A | 2 |
| Alastruey-Izquierdo, A | 2 |
| Rodriguez, D | 1 |
| Almirante, B | 1 |
| Pahissa, A | 1 |
| Rodriguez-Tudela, JL | 3 |
| Cuenca-Estrella, M | 3 |
| Chapeland-Leclerc, F | 1 |
| Hennequin, C | 1 |
| Papon, N | 1 |
| Noël, T | 1 |
| Girard, A | 1 |
| Socié, G | 1 |
| Ribaud, P | 1 |
| Lacroix, C | 2 |
| Murphy, LS | 1 |
| Lacy, AJ | 1 |
| Smith, AT | 1 |
| Shah, KS | 1 |
| Falces-Romero, I | 1 |
| Cendejas-Bueno, E | 1 |
| Romero-Gómez, MP | 1 |
| García-Rodríguez, J | 1 |
| Trpković, A | 1 |
| Pekmezović, M | 1 |
| Barać, A | 1 |
| Crnčević Radović, L | 1 |
| Arsić Arsenijević, V | 1 |
| Chen, M | 1 |
| Wang, X | 1 |
| Yu, X | 1 |
| Dai, C | 1 |
| Chen, D | 1 |
| Yu, C | 1 |
| Xu, X | 1 |
| Yao, D | 1 |
| Yang, L | 1 |
| Li, Y | 1 |
| Wang, L | 1 |
| Huang, X | 1 |
| Zhu, TH | 1 |
| Rodriguez, PG | 1 |
| Behan, JW | 1 |
| Declerck, B | 1 |
| Kim, GH | 1 |
| Araujo Ribeiro, M | 1 |
| Pahud, BA | 1 |
| Greenhow, TL | 1 |
| Piecuch, B | 1 |
| Weintrub, PS | 1 |
| Gonçalves, SS | 1 |
| Amorim, CS | 1 |
| Nucci, M | 1 |
| Padovan, AC | 1 |
| Briones, MR | 1 |
| Melo, AS | 1 |
| Colombo, AL | 1 |
| Dannaoui, E | 1 |
| Paugam, A | 1 |
| Develoux, M | 1 |
| Chochillon, C | 1 |
| Matheron, J | 1 |
| Datry, A | 1 |
| Bouges-Michel, C | 1 |
| Bonnal, C | 1 |
| Dromer, F | 2 |
| Bretagne, S | 2 |
| Krishnan, S | 1 |
| Ostrosky-Zeichner, L | 1 |
| Hamoud, S | 1 |
| Keidar, Z | 1 |
| Hayek, T | 1 |
| Bliss, JM | 1 |
| Wellington, M | 1 |
| Gigliotti, F | 1 |
| Pfaller, MA | 1 |
| Diekema, DJ | 1 |
| Messer, SA | 1 |
| Boyken, L | 1 |
| Hollis, RJ | 1 |
| Wertz, KK | 1 |
| Pretzlaff, RK | 1 |
| Fine, HF | 1 |
| Chang, MA | 1 |
| Dunn, JP | 1 |
| Marr, KA | 1 |
| Salet, J | 1 |
| Weissgerber, G | 1 |
| Chirazi, MT | 1 |
| Brunelle, F | 1 |
| Natarajan, G | 1 |
| Lulic-Botica, M | 1 |
| Rongkavilit, C | 1 |
| Pappas, A | 1 |
| Bedard, M | 1 |
| Bakir, M | 1 |
| Cerikcioglu, N | 1 |
| Barton, R | 1 |
| Yagci, A | 1 |
| van der Voort, PH | 1 |
| Boerma, EC | 1 |
| Yska, JP | 1 |
| Desnos-Ollivier, M | 1 |
| Bernède, C | 1 |
| Robert, V | 1 |
| Raoux, D | 1 |
| Chachaty, E | 1 |
| Forget, E | 1 |
| Kinyoun, JL | 1 |
| Burgert, SJ | 1 |
| Classen, DC | 1 |
| Burke, JP | 1 |
| Blatter, DD | 1 |
| Kamitsuka, MD | 1 |
| Nugent, NA | 1 |
| Conrad, PD | 1 |
| Swanson, TN | 1 |
| Berenguer, J | 1 |
| Fernández-Baca, V | 1 |
| Sánchez, R | 1 |
| Bouza, E | 1 |
| Stamos, JK | 1 |
| Rowley, AH | 1 |
| Solomkin, JS | 1 |
| Villareal, KM | 1 |
| Cook, RA | 1 |
| Galgiani, JN | 1 |
| Wenzel, RP | 1 |
| Pappas, PG | 1 |
| Pottage, JC | 1 |
| Gallis, HA | 1 |
| Crane, LR | 1 |
| Ponnuvel, KM | 1 |
| Rama, CP | 1 |
| Menon, T | 1 |
| Nolte, FS | 1 |
| Parkinson, T | 1 |
| Falconer, DJ | 1 |
| Dix, S | 1 |
| Williams, J | 1 |
| Gilmore, C | 1 |
| Geller, R | 1 |
| Wingard, JR | 1 |
| Scherer, WJ | 1 |
| Lee, K | 1 |
| de Pauw, BE | 2 |
| Meunier, F | 2 |
| Kullberg, BJ | 1 |
| Cawley, MJ | 1 |
| Braxton, GR | 1 |
| Haith, LR | 1 |
| Reilly, KJ | 1 |
| Guilday, RE | 1 |
| Patton, ML | 1 |
| Krcmery, V | 1 |
| Jurga, L | 1 |
| Mateicka, F | 1 |
| Sulcová, M | 1 |
| Sanglard, D | 1 |
| Odds, FC | 1 |
| Harms, K | 1 |
| Herting, E | 1 |
| Schiffmann, JH | 1 |
| Speer, CP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| SEIFEM 2015: Fungemia in Hematologic Malignancies[NCT02451592] | 300 participants (Actual) | Observational | 2011-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for flucytosine and Fungemia
| Article | Year |
|---|---|
Pleural effusion as the initial clinical presentation in disseminated cryptococcosis and fungaemia: an unusual manifestation and a literature review.
Topics: Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Fluconazole; Flucytosine | 2015 |
Antifungal pharmacotherapy for neonatal candidiasis.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Cross Infection; Echinocandins; Flucona | 2003 |
Invasive Candida infections: the changing epidemiology.
Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candidiasis; Drug Resistance, Fungal | 2004 |
Candidemia in a pediatric population.
Topics: Adolescent; Age Distribution; Amphotericin B; Candidiasis; Child; Child, Preschool; Drug Therapy, Co | 1995 |
Pathogenesis and management of Candida infection syndromes in non-neutropenic patients.
Topics: Amphotericin B; Candidiasis; Clinical Trials as Topic; Cross Infection; Fluconazole; Flucytosine; Fu | 1993 |
The challenge of invasive fungal infection.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis | 1999 |
Therapy of invasive fungal infections.
Topics: Amphotericin B; Antifungal Agents; Catheterization, Central Venous; Contraindications; Drug Therapy, | 1999 |
Trichosporon beigelii infection: experience in a regional burn center.
Topics: Adult; Amphotericin B; Antifungal Agents; Burns; Catheters, Indwelling; Drug Resistance, Microbial; | 2000 |
Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida; Candidiasis; Cytochrome P-450 Enzyme System; Dru | 2002 |
34 other studies available for flucytosine and Fungemia
| Article | Year |
|---|---|
In vitro activities of isavuconazole and other antifungal agents against Candida bloodstream isolates.
Topics: Antifungal Agents; Area Under Curve; Candida; Fungemia; Humans; Microbial Sensitivity Tests; Nitrile | 2007 |
Antimicrobial activity of omiganan pentahydrochloride against contemporary fungal pathogens responsible for catheter-associated infections.
Topics: Antifungal Agents; Antimicrobial Cationic Peptides; Aspergillosis; Aspergillus; Candida; Candidiasis | 2008 |
Prevalence and susceptibility profile of Candida metapsilosis and Candida orthopsilosis: results from population-based surveillance of candidemia in Spain.
Topics: Antifungal Agents; Candida; Candidiasis; Fungemia; Humans; Microbial Sensitivity Tests; Population S | 2008 |
Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient.
Topics: Antifungal Agents; Azoles; Candida glabrata; Candidiasis; Caspofungin; Child; Drug Resistance, Funga | 2010 |
Cryptococcal meningitis in an immunocompetent patient.
Topics: Adult; Amphotericin B; Antifungal Agents; Culture Techniques; Delayed Diagnosis; Fluconazole; Flucyt | 2020 |
Isolation of Rhodotorula mucilaginosa from blood cultures in a tertiary care hospital.
Topics: Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Azoles; Blood Culture; Child, Preschool; | 2018 |
In vitro antifungal activities of amphotericin B, 5-fluorocytosine, fluconazole and itraconazole against Cryptococcus neoformans isolated from cerebrospinal fluid and blood from patients in Serbia.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cerebrospinal Fluid; Cross | 2012 |
Cryptococcal cellulitis on the shin of an immunosuppressed patient.
Topics: Amphotericin B; Antifungal Agents; Cellulitis; Cryptococcosis; Cryptococcus neoformans; Cyclosporine | 2016 |
Molecular identification and susceptibility testing of Trichosporon isolates from a Brazilian hospital.
Topics: Amphotericin B; Antifungal Agents; Brazil; Cross Infection; Dermatomycoses; Drug Resistance, Fungal; | 2008 |
Preterm neonates with candidal brain microabscesses: a case series.
Topics: Amphotericin B; Antifungal Agents; Brain; Brain Abscess; Candidiasis; Deoxycholic Acid; Drug Combina | 2009 |
Prevalence rates and antifungal susceptibility profiles of the Candida parapsilosis species complex: results from a nationwide surveillance of candidaemia in Brazil.
Topics: Antifungal Agents; Brazil; Candida; Candidiasis; Caspofungin; DNA, Fungal; Drug Resistance, Fungal; | 2010 |
Comparison of antifungal MICs for yeasts obtained using the EUCAST method in a reference laboratory and the Etest in nine different hospital laboratories.
Topics: Amphotericin B; Antifungal Agents; Candida; Caspofungin; Cryptococcus neoformans; Drug Resistance, F | 2010 |
Invasive candidiasis in the intensive care unit.
Topics: Algorithms; Antifungal Agents; Azoles; Biomarkers; Candidiasis; Chemoprevention; Critical Care; Cros | 2010 |
Recurrent Saccharomyces cerevisiae fungemia in an otherwise healthy patient.
Topics: Abdominal Pain; Adult; Amphotericin B; Antifungal Agents; Chills; Diagnosis, Differential; Female; F | 2011 |
In vitro susceptibilities of rare Candida bloodstream isolates to ravuconazole and three comparative antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Flucy | 2004 |
Caspofungin in a pediatric patient with persistent candidemia.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Child, Preschool; Drug Therapy, Combina | 2004 |
Bilateral cryptococcal choroiditis.
Topics: Adult; Antifungal Agents; Choroiditis; Cryptococcosis; Cryptococcus neoformans; Dermatomycoses; Eye | 2004 |
[Atresia of the small intestine, cystic fibrosis and septicemia due to Candida albicans in a newborn].
Topics: Acute Disease; Antifungal Agents; Candida albicans; Candidiasis; Cystic Fibrosis; Flucytosine; Funge | 1976 |
Experience with caspofungin in the treatment of persistent fungemia in neonates.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Drug Therapy, Combination; Echinocandin | 2005 |
Epidemiology of candidemia in a Turkish tertiary care hospital.
Topics: Amphotericin B; Antifungal Agents; Blotting, Southern; Candida; Candidiasis; Cross Infection; DNA Fi | 2006 |
Serum and intraperitoneal levels of amphotericin B and flucytosine during intravenous treatment of critically ill patients with Candida peritonitis.
Topics: Aged; Amphotericin B; Ascitic Fluid; Candidiasis; Critical Care; Female; Flucytosine; Fungemia; Huma | 2007 |
Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France.
Topics: Antifungal Agents; Candida tropicalis; Candidiasis; Drug Resistance, Fungal; Flucytosine; France; Fu | 2008 |
Treatment of Candida endophthalmitis.
Topics: Amphotericin B; Candidiasis; Cataract Extraction; Endophthalmitis; Eye Infections, Fungal; Fibrosis; | 1982 |
Candidal brain abscess associated with vascular invasion: a devastating complication of vascular catheter-related candidemia.
Topics: Amphotericin B; Arterial Occlusive Diseases; Brain; Brain Abscess; Candida albicans; Candidiasis; Ca | 1995 |
Candida albicans brain abscesses in a premature infant treated with amphotericin B, flucytosine and fluconazole.
Topics: Amphotericin B; Brain Abscess; Candidiasis; Drug Therapy, Combination; Female; Fluconazole; Flucytos | 1995 |
In vitro activity of amphotericin B, flucytosine and fluconazole against yeasts causing bloodstream infections.
Topics: Amphotericin B; Fluconazole; Flucytosine; Fungemia; Humans; Microbial Sensitivity Tests; Yeasts | 1995 |
Comparative analysis of three antifungal susceptibility test methods against prospectively collected Candida species.
Topics: Amphotericin B; Candida; Candidiasis; Drug Resistance, Microbial; Echinocandins; Esophagitis; Evalua | 1994 |
Systemic and gastrointestinal candidiasis of infant mice as model for antifungal therapy.
Topics: Amphotericin B; Animals; Candidiasis; Disease Models, Animal; Fluconazole; Flucytosine; Fungemia; Ga | 1993 |
Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia.
Topics: Adolescent; Adult; Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Drug R | 1997 |
Implications of early systemic therapy on the incidence of endogenous fungal endophthalmitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Child; Child, Pres | 1997 |
[A multicenter study on fungemia caused by yeasts in Spain (April-June, 1997). A Work Group to Study Fungemia)].
Topics: Adult; Age Factors; Aged; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Cross-Sectional S | 1999 |
Fungaemia in elderly patients.
Topics: Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candidiasis; Cross Infection; Female; Fl | 2001 |
[Candida infections in premature infants weighing less than 1,500 g. Mucocutaneous colonization and incidence of systemic infections].
Topics: Candidiasis, Chronic Mucocutaneous; Cesarean Section; Cross Infection; Cross-Sectional Studies; Drug | 1992 |
Systemic candidal infections in neonates.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Flucytosine; Fungemia; Humans; Infant, Newbo | 1992 |