flucytosine has been researched along with Endocarditis in 44 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Endocarditis: Inflammation of the inner lining of the heart (ENDOCARDIUM), the continuous membrane lining the four chambers and HEART VALVES. It is often caused by microorganisms including bacteria, viruses, fungi, and rickettsiae. Left untreated, endocarditis can damage heart valves and become life-threatening.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the efficacies of fluconazole (Flu), amphotericin B (AmB), and 5-fluorocytosine (5FC) monotherapies with the combination of Flu plus 5FC and Flu plus AmB in a rabbit model of Candida albicans endocarditis, endophthalmitis, and pyelonephritis." | 7.70 | Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d ( Drusano, GL; Liu, QF; Liu, W; Louie, A; Mayers, M; Miller, DA; Miller, MH; Sucke, AC, 1999) |
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 7.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| "A 7-year-old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae and was treated successfully with orally administered antifungal agent, namely 5-fluorocytosine (5-FC)." | 7.65 | Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine. ( Friedman, A; Hashman, N; Merzbach, D; Naveh, Y, 1975) |
| "We compared the efficacies of fluconazole (Flu), amphotericin B (AmB), and 5-fluorocytosine (5FC) monotherapies with the combination of Flu plus 5FC and Flu plus AmB in a rabbit model of Candida albicans endocarditis, endophthalmitis, and pyelonephritis." | 3.70 | Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d ( Drusano, GL; Liu, QF; Liu, W; Louie, A; Mayers, M; Miller, DA; Miller, MH; Sucke, AC, 1999) |
| "The efficacy of amphotericin B, 5-fluorocytosine and itraconazole was compared for the treatment of experimental rabbit Aspergillus fumigatus endocarditis." | 3.67 | A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit. ( Longman, LP; Martin, MV, 1987) |
| " Serum and cultural data as well as the excellent response to treatment with 5-flucytosine seems to confirm the diagnosis of candida infection." | 3.67 | [A case of mycotic endocarditis. Clinical, diagnostic and therapeutic considerations]. ( Campisi, E; Cecchi, F; Faggi, E; Lampronti, V; Niosi, L, 1985) |
| "A 7-year-old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae and was treated successfully with orally administered antifungal agent, namely 5-fluorocytosine (5-FC)." | 3.65 | Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine. ( Friedman, A; Hashman, N; Merzbach, D; Naveh, Y, 1975) |
| " The proper duration and dosage and the combination of antifungal drugs have not been clearly defined." | 2.38 | [Primary Aspergillus endocarditis. Apropos of a case and review of the international literature]. ( Cajot, MA; Gosselin, B; Goullard, L; Koussa, A; Marquette, F; Pol, A; Roux, JP; Soots, G; Warembourg, H, 1992) |
| "Endocarditis is an uncommon complication of disseminated candidiasis among premature infants, but has been recently reported to be almost uniformly fatal." | 1.28 | Successful medical treatment of Candida parapsilosis endocarditis in a premature infant. ( Faix, RG; Feick, HJ; Frommelt, P; Snider, AR, 1990) |
| "Aspergillus endocarditis is associated with a very high mortality." | 1.27 | Successful treatment of post-mitral valve annuloplasty Aspergillus flavus endocarditis. ( Bonchek, LI; Rytel, MW; Shimshak, T; Wagner, DK; Werner, PH, 1985) |
| "Successful treatment of fungal endocarditis is being described with increasing frequency." | 1.26 | Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported. ( Galgiani, JN; Stevens, DA, 1977) |
| "In addition to arterial embolism, occult mycotic aneurysms were found by arteriography." | 1.26 | Treatment of Candida endocarditis and arteritis. ( Cerruti, MM; Friedman, SA; Gladstone, JL; Jomain, SL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (65.91) | 18.7374 |
| 1990's | 8 (18.18) | 18.2507 |
| 2000's | 5 (11.36) | 29.6817 |
| 2010's | 2 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guragai, N | 1 |
| Rampal, U | 1 |
| Vasudev, R | 1 |
| Shah, D | 1 |
| Patel, H | 1 |
| Salamera, J | 1 |
| Pullatt, R | 1 |
| Shamoon, F | 1 |
| Chiron, LM | 1 |
| Pihet, M | 1 |
| Rouleau, F | 1 |
| de Gentile, L | 1 |
| Bouchara, JP | 1 |
| Chabasse, D | 1 |
| Pai, MP | 2 |
| Bouraoui, H | 1 |
| Mahdhaoui, A | 1 |
| Zaaraoui, J | 1 |
| Mejdoub, M | 1 |
| Ernez-Hajri, S | 1 |
| Jeridi, G | 1 |
| Ammar, H | 1 |
| Wertz, KK | 1 |
| Pretzlaff, RK | 1 |
| Samples, ML | 1 |
| Mercier, RC | 1 |
| Spilde, MN | 1 |
| Samelson, LE | 1 |
| Lerner, SA | 1 |
| Resnekov, L | 1 |
| Anagnostopoulos, C | 1 |
| Vishniavsky, N | 1 |
| Sagar, KB | 1 |
| Markowitz, SM | 1 |
| Miyazono, K | 1 |
| Yoshida, M | 1 |
| Kitagawa, S | 1 |
| Tsuboyama, A | 1 |
| Sakamoto, S | 1 |
| Miura, Y | 1 |
| Shina, A | 1 |
| Darwazah, A | 1 |
| Berg, G | 1 |
| Faris, B | 1 |
| Louie, A | 1 |
| Liu, W | 1 |
| Miller, DA | 1 |
| Sucke, AC | 1 |
| Liu, QF | 1 |
| Drusano, GL | 1 |
| Mayers, M | 1 |
| Miller, MH | 1 |
| Jones, JM | 1 |
| Sarsam, MA | 1 |
| Clarke, MA | 1 |
| Hedderwick, SA | 1 |
| Sande, MA | 1 |
| Bowman, CR | 1 |
| Calderone, RA | 1 |
| Demierre, G | 1 |
| Freedman, LR | 1 |
| Martin, E | 1 |
| Pancoast, SJ | 1 |
| Neu, HC | 1 |
| Wain, W | 1 |
| Ahmed, M | 1 |
| Thompson, R | 1 |
| Yacoub, M | 1 |
| Drouhet, E | 1 |
| Dupont, B | 1 |
| Mayrer, AR | 1 |
| Brown, A | 1 |
| Weintraub, RA | 1 |
| Ragni, M | 1 |
| Postic, B | 1 |
| Galgiani, JN | 1 |
| Stevens, DA | 1 |
| Rotheram, EB | 1 |
| Magovern, GJ | 1 |
| Gladstone, JL | 1 |
| Friedman, SA | 1 |
| Cerruti, MM | 1 |
| Jomain, SL | 1 |
| Sharpe, DN | 1 |
| Singh, BN | 1 |
| Cornere, BM | 1 |
| Allwood, GK | 1 |
| Premsingh, N | 1 |
| Kapila, R | 1 |
| Tecson, F | 1 |
| Smith, LG | 1 |
| Louria, DB | 1 |
| Darrell, JH | 1 |
| Naveh, Y | 1 |
| Friedman, A | 1 |
| Merzbach, D | 1 |
| Hashman, N | 1 |
| Rubinstein, E | 1 |
| Noriega, ER | 1 |
| Simberkoff, MS | 1 |
| Holzman, R | 1 |
| Rahal, JJ | 1 |
| Stone, DL | 1 |
| Roux, JP | 1 |
| Koussa, A | 1 |
| Cajot, MA | 1 |
| Marquette, F | 1 |
| Goullard, L | 1 |
| Gosselin, B | 1 |
| Pol, A | 1 |
| Warembourg, H | 1 |
| Soots, G | 1 |
| Zenker, PN | 1 |
| Rosenberg, EM | 1 |
| Van Dyke, RB | 1 |
| Rabalais, GP | 1 |
| Daum, RS | 1 |
| Sánchez, PJ | 1 |
| Siegel, JD | 1 |
| Fishbein, J | 1 |
| Kasugai, H | 1 |
| Watanabe, Y | 1 |
| Nakamura, T | 1 |
| Sotozono, K | 1 |
| Asahi, Y | 1 |
| Murayama, M | 1 |
| Sugai, J | 1 |
| Okada, T | 1 |
| Kawada, T | 1 |
| Abe, M | 1 |
| Bogner, JR | 1 |
| Lüftl, S | 1 |
| Middeke, M | 1 |
| Spengel, F | 1 |
| Faix, RG | 1 |
| Feick, HJ | 1 |
| Frommelt, P | 1 |
| Snider, AR | 1 |
| Longman, LP | 1 |
| Martin, MV | 1 |
| Wagner, DK | 1 |
| Werner, PH | 1 |
| Bonchek, LI | 1 |
| Shimshak, T | 1 |
| Rytel, MW | 1 |
| Lampronti, V | 1 |
| Niosi, L | 1 |
| Campisi, E | 1 |
| Faggi, E | 1 |
| Cecchi, F | 1 |
| Acar, J | 1 |
| Cabrol, C | 1 |
| Jallut, H | 1 |
| Frottier, J | 1 |
| Duron, F | 1 |
| Bastin, R | 1 |
| Logan, RL | 1 |
| Goldberg, MJ | 1 |
| Harford, CG | 1 |
| Montague, NT | 1 |
| Sugg, WL | 1 |
| Carrizosa, J | 1 |
| Levison, ME | 1 |
| Lawrence, T | 1 |
| Kaye, D | 1 |
| Hoeprich, PD | 1 |
| Ingraham, JL | 1 |
| Kleker, E | 1 |
| Winship, MJ | 1 |
| Harris, PD | 1 |
| Yeoh, CB | 1 |
| Breault, J | 1 |
| Meltzer, J | 1 |
| Katz, S | 1 |
| Record, CO | 1 |
| Skinner, JM | 1 |
| Sleight, P | 1 |
| Speller, DC | 1 |
3 reviews available for flucytosine and Endocarditis
| Article | Year |
|---|---|
Candida endocarditis in two patients.
Topics: Adolescent; Amphotericin B; Aortic Valve; Candidiasis; Drug Therapy, Combination; Endocarditis; Fluc | 1976 |
[Primary Aspergillus endocarditis. Apropos of a case and review of the international literature].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Combined Modality Therapy; | 1992 |
Candida endocarditis: successful medical management in three preterm infants and review of the literature.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Endocarditis; Female; Flucytosine; Humans; I | 1991 |
41 other studies available for flucytosine and Endocarditis
| Article | Year |
|---|---|
Isolated Pulmonary Valve Fungal Endocarditis with Candida parapsilosis: Management Considerations of a Rare Case.
Topics: Administration, Intravenous; Adult; Amphotericin B; Antifungal Agents; Candida parapsilosis; Candidi | 2017 |
[Comment on this case report].
Topics: Adult; Amphotericin B; Antifungal Agents; Buprenorphine; Candidiasis; Endocarditis; Endophthalmitis; | 2012 |
Antifungal combinations against simulated Candida albicans endocardial vegetations.
Topics: Amphotericin B; Antifungal Agents; Biofilms; Candida albicans; Drug Combinations; Echinocandins; End | 2009 |
[Candida albicans prosthetic valve endocarditis. Two cases].
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Drug Therapy, Combination; Endocar | 2002 |
Caspofungin in a pediatric patient with persistent candidemia.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Child, Preschool; Drug Therapy, Combina | 2004 |
Activities and ultrastructural effects of antifungal combinations against simulated Candida endocardial vegetations.
Topics: Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis; Dru | 2008 |
Relapse of Candida parapsilosis endocarditis after long-term suppression with flucytosin: retreatment with valve replacement and ketoconazole.
Topics: Adult; Amphotericin B; Candidiasis; Cytosine; Drug Therapy, Combination; Endocarditis; Female; Flucy | 1980 |
Aspergillus fumigatus endocarditis on a normal heart valve.
Topics: Aged; Amphotericin B; Aspergillosis; Aspergillus fumigatus; Bioprosthesis; Drug Therapy, Combination | 1983 |
[Pulmonary aspergillosis associated with endocarditis and cerebral embolism in a case of acute myeloblastic leukemia].
Topics: Amphotericin B; Aspergillosis; Aspergillus fumigatus; Endocarditis; Flucytosine; Humans; Intracrania | 1984 |
Candida parapsilosis: an unusual organism causing prosthetic heart valve infective endocarditis.
Topics: Aged; Amphotericin B; Antifungal Agents; Aortic Valve; C-Reactive Protein; Candida; Candidiasis; Dru | 1999 |
Efficacies of high-dose fluconazole plus amphotericin B and high-dose fluconazole plus 5-fluorocytosine versus amphotericin B, fluconazole, and 5-fluorocytosine monotherapies in treatment of experimental endocarditis, endophthalmitis, and pyelonephritis d
Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Creatinine; Endocarditis; | 1999 |
Candida parapsilosis: two cases of endocarditis in association with the Toronto stentless porcine valve.
Topics: Aged; Aged, 80 and over; Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis; Endocardi | 2002 |
Experimental Candida albicans endocarditis: characterization of the disease and response to therapy.
Topics: Agglutinins; Amphotericin B; Animals; Antibodies, Fungal; Aortic Valve; Candida albicans; Candidiasi | 1977 |
Experimental endocarditis: prophylaxis of Candida albicans infections by 5-fluorocytosine in rabbits.
Topics: Animals; Candida albicans; Candidiasis; Cytosine; Drug Resistance, Microbial; Embolism; Endocarditis | 1979 |
Candida parapsilosis endocarditis: medical and surgical cure.
Topics: Adult; Amphotericin B; Aortic Valve; Candidiasis; Endocarditis; Flucytosine; Humans; Male | 1979 |
The role of chemotherapy in the management of fungal endocaridits following homograft valve replacement.
Topics: Amphotericin B; Endocarditis; Flucytosine; Heart Valves; Humans; Mycoses; Postoperative Complication | 1979 |
[Iatrogenic mycoses with deep visceral localization caused by opportunistic fungi].
Topics: Amphotericin B; Candida; Candidiasis; Cryptococcosis; Dermatomycoses; Endocarditis; Flucytosine; Hum | 1979 |
Successful medical therapy for endocarditis due to Candida parapsilosis. A clinical and epidemiologic study.
Topics: Adult; Amphotericin B; Candida; Candidiasis; Endocarditis; Flucytosine; Humans; Male | 1978 |
Fungal endocarditis: need for guidelines in evaluating therapy. Experience with two patients previously reported.
Topics: Adult; Amphotericin B; Aortic Valve Stenosis; Candidiasis; Cytosine; Endocarditis; Flucytosine; Hear | 1977 |
Two-year cure of Candida infection of prosthetic mitral valve.
Topics: Amphotericin B; Atrial Fibrillation; Candidiasis; Digoxin; Embolism; Endocarditis; Female; Flucytosi | 1977 |
Treatment of Candida endocarditis and arteritis.
Topics: Adult; Amphotericin B; Aneurysm, Infected; Aortography; Arterial Occlusive Diseases; Arteritis; Cand | 1976 |
Torulopsis glabrata endocarditis complicating aortic homograft valve treated with 5-fluorocytosine: case report with discussion of antifungal chemotherapy.
Topics: Amphotericin B; Aortic Valve; Aortic Valve Stenosis; Autopsy; Candida; Candidiasis; Cytosine; Endoca | 1975 |
Letter: Candida endocarditis.
Topics: Amphotericin B; Candidiasis; Endocarditis; Flucytosine; Humans | 1975 |
Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine.
Topics: Administration, Oral; Antifungal Agents; Aortic Valve Insufficiency; Candidiasis; Child; Cytosine; E | 1975 |
Fungal endocarditis: analysis of 24 cases and review of the literature.
Topics: Adolescent; Adult; Aged; Amphotericin B; Aspergillosis; Candida; Candidiasis; Cardiac Surgical Proce | 1975 |
Candida endocarditis treated with a combination of antifungal chemotherapy and aortic valve replacement.
Topics: Amphotericin B; Aortic Valve; Candidiasis; Endocarditis; Flucytosine; Heart Valve Prosthesis; Humans | 1975 |
Successful medical treatment of presumed Candida endocarditis in critically ill infants.
Topics: Amphotericin B; Candidiasis; Drug Therapy, Combination; Endocarditis; Female; Flucytosine; Humans; I | 1991 |
[A successfully treated case of infective endocarditis due to Candida tropicalis].
Topics: Adult; Amphotericin B; Candida; Candidiasis; Drug Therapy, Combination; Endocarditis; Flucytosine; H | 1990 |
[Successful drug therapy in Aspergillus endocarditis].
Topics: Aged; Amphotericin B; Amputation, Surgical; Aortic Valve; Aspergillosis; Aspergillus fumigatus; Comb | 1990 |
Successful medical treatment of Candida parapsilosis endocarditis in a premature infant.
Topics: Amphotericin B; Candidiasis; Endocarditis; Flucytosine; Humans; Infant, Newborn; Infant, Premature, | 1990 |
A comparison of the efficacy of itraconazole, amphotericin B and 5-fluorocytosine in the treatment of Aspergillus fumigatus endocarditis in the rabbit.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Endocarditis; Fluc | 1987 |
Successful treatment of post-mitral valve annuloplasty Aspergillus flavus endocarditis.
Topics: Amphotericin B; Aspergillosis; Aspergillus flavus; Combined Modality Therapy; Cytosine; Endocarditis | 1985 |
[A case of mycotic endocarditis. Clinical, diagnostic and therapeutic considerations].
Topics: Adolescent; Anorexia; Benzodiazepines; Candidiasis; Depression; Dibenzocycloheptenes; Echocardiograp | 1985 |
[Candida endocarditis in mitral prosthesis (apropos of a case cured by a second operation)].
Topics: Amphotericin B; Candida; Candidiasis; Endocarditis; Female; Flucytosine; Heart Valve Prosthesis; Hum | 1973 |
C. albicans resistance to 5-fluorocytosine.
Topics: Antifungal Agents; Candida albicans; Candidiasis; Cytosine; Drug Resistance, Microbial; Endocarditis | 1972 |
Postoperative fungal endocarditis. Fungemia, embolism, and therapy.
Topics: Aged; Amphotericin B; Aortic Valve; Aspergillus; Blood; Candida; Candida albicans; Cryptococcus; Emb | 1974 |
Candida endocarditis with femoral emboli. Treatment with surgery and 5-fluorocytosine.
Topics: Antifungal Agents; Aortic Valve; Candidiasis; Cytosine; Embolism; Endocarditis; Femoral Artery; Fluc | 1974 |
Cure of Aspergillus ustus endocarditis on a prosthetic valve.
Topics: Amphotericin B; Aortic Valve; Aspergillosis; Aspergillus; Drug Therapy, Combination; Endocarditis; F | 1974 |
Development of resistance to 5-fluorocytosine in Candida parapsilosis during therapy.
Topics: Adult; Aminohydrolases; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Cell-Free System; C | 1974 |
Fungal endocarditis secondary to drug addiction. Recent concepts in diagnosis and therapy.
Topics: Adult; Amphotericin B; Aortic Valve Insufficiency; Benzene Derivatives; Candidiasis; Endocarditis; F | 1972 |
Candida endocarditis treated with 5-fluorocytosine.
Topics: Aged; Bone Marrow Diseases; Candidiasis; Endocarditis; Female; Flucytosine; Heart Valve Prosthesis; | 1971 |