flucytosine has been researched along with Cytomegalovirus in 6 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Ovcar-5 and Skov-3 ovarian cancer cell lines exposed to the Ad-Lp-CD adenoviral vector were much more sensitive to the prodrug 5-fluorocytosine (5FC), which is converted from the 5FC prodrug into the toxic chemical 5-fluorouracil, than was the CCD minimal deviation fibroblast cell line after exposure to the same vector." | 1.31 | The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines. ( Crystal, R; Deisseroth, A; Fujii, T; Kacinski, B; Leavitt, J; Peng, XY; Pizzorno, G; Rutherford, T; Sapi, E; Schwartz, P; Won, JH; Zelterman, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bezborodova, OA | 1 |
| Nemtsova, ER | 1 |
| Gevorkov, AR | 1 |
| Boyko, AV | 1 |
| Venediktova, JB | 1 |
| Alekseenko, IV | 1 |
| Kostina, MB | 1 |
| Monastyrskaya, GS | 1 |
| Sverdlov, ED | 1 |
| Khmelevskiy, EV | 1 |
| Yakubovskaya, RI | 1 |
| Zhang, J | 1 |
| Wei, F | 1 |
| Wang, H | 1 |
| Li, H | 1 |
| Qiu, W | 1 |
| Ren, P | 1 |
| Chen, X | 1 |
| Huang, Q | 1 |
| Li, XJ | 1 |
| Wang, KM | 1 |
| Xu, Y | 1 |
| Wang, ZH | 1 |
| Xia, AD | 1 |
| Chen, SS | 1 |
| Qian, GX | 1 |
| Blackburn, RV | 1 |
| Galoforo, SS | 1 |
| Corry, PM | 1 |
| Lee, YJ | 1 |
| Peng, XY | 1 |
| Won, JH | 1 |
| Rutherford, T | 1 |
| Fujii, T | 1 |
| Zelterman, D | 1 |
| Pizzorno, G | 1 |
| Sapi, E | 1 |
| Leavitt, J | 1 |
| Kacinski, B | 1 |
| Crystal, R | 1 |
| Schwartz, P | 1 |
| Deisseroth, A | 1 |
| Miller, CR | 1 |
| Gustin, AN | 1 |
| Buchsbaum, DJ | 1 |
| Vickers, SM | 1 |
| Manne, U | 1 |
| Grizzle, WE | 1 |
| Cloud, GA | 1 |
| Diasio, RB | 1 |
| Johnson, MR | 1 |
6 other studies available for flucytosine and Cytomegalovirus
| Article | Year |
|---|---|
Antitumor efficacy of combined gene and radiotherapy in animals.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colonic Neoplasms; Combi | 2016 |
A novel oncolytic adenovirus expressing Escherichia coli cytosine deaminase exhibits potent antitumor effect on human solid tumors.
Topics: Adenoviridae; Adenoviridae Infections; Adenovirus E1A Proteins; Animals; Antimetabolites; Blotting, | 2010 |
[Ionizing radiation-regulated killing of human hepatoma cells by liposome-mediated CDglyTK gene delivery].
Topics: Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Survival; Cytomegalovirus; Cy | 2003 |
Adenoviral transduction of a cytosine deaminase/thymidine kinase fusion gene into prostate carcinoma cells enhances prodrug and radiation sensitivity.
Topics: Adenoviridae; Animals; Antimetabolites; Antimetabolites, Antineoplastic; Antiviral Agents; Carcinoma | 1999 |
The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines.
Topics: Adenoviridae; Animals; Cytomegalovirus; Cytosine Deaminase; Female; Flucytosine; Fluorouracil; Gene | 2001 |
Quantitation of cytosine deaminase mRNA by real-time reverse transcription polymerase chain reaction: a sensitive method for assessing 5-fluorocytosine toxicity in vitro.
Topics: Antimetabolites; Carcinoma; Cell Survival; Colonic Neoplasms; Cytomegalovirus; Cytosine Deaminase; F | 2002 |