Page last updated: 2024-10-27

flucytosine and Central Nervous System Diseases

flucytosine has been researched along with Central Nervous System Diseases in 10 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

Research Excerpts

ExcerptRelevanceReference
"Results obtained in the treatment of cryptococcosis of the central nervous system with amphotericin-B, 5-fluorocytosine and miconazole are evaluated."7.66[Cryptococcosis of the central nervous system: evaluation of amphotericin-B, 5-fluorocytosine and miconazole therapy in 18 cases]. ( Livramento, JA; Machado, LR; Nobrega, JP; Spina-França, A, 1979)
"The drugs used in the treatment of CNS cryptococcosis were, as possible, the amphotericin B by intravenous and intrathecal route (lumbar puncture) associated with 5-fluorocytosine."5.27[Amphotericin B in the treatment of neurocryptococcosis in patients subjected to renal transplantation]. ( Nóbrega, JP, 1988)
"Results obtained in the treatment of cryptococcosis of the central nervous system with amphotericin-B, 5-fluorocytosine and miconazole are evaluated."3.66[Cryptococcosis of the central nervous system: evaluation of amphotericin-B, 5-fluorocytosine and miconazole therapy in 18 cases]. ( Livramento, JA; Machado, LR; Nobrega, JP; Spina-França, A, 1979)
"Amphotericin B has remained the most effective therapeutic preparation for most types of neurological fungal disease, although important roles for 5-fluorocytosine, miconazole, and, more recently, ketoconazole are being recognized."2.36Treatment of fungal infections of the central nervous system. ( Bell, WE, 1981)
"Treatment with fluconazole is only recommended for localised pulmonary disease."1.62Treatment and mortality outcomes in patients with other extrapulmonary cryptococcal disease compared with central nervous system disease. ( Larson, L; Mejia-Chew, C; Powderly, WG; Spec, A; Sung, A, 2021)
"The drugs used in the treatment of CNS cryptococcosis were, as possible, the amphotericin B by intravenous and intrathecal route (lumbar puncture) associated with 5-fluorocytosine."1.27[Amphotericin B in the treatment of neurocryptococcosis in patients subjected to renal transplantation]. ( Nóbrega, JP, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Mejia-Chew, C1
Sung, A1
Larson, L1
Powderly, WG1
Spec, A1
Faix, RG1
Bell, WE1
Fujita, N1
Grinnell, V1
Edwards, JE1
Feldman, RA1
Nobrega, JP2
Livramento, JA1
Machado, LR1
Spina-França, A1
Cochius, JI1
Burns, RJ1
Willoughby, JO1
Scholer, HJ1
Sabetta, JR1
Andriole, VT1
Neuhaus, F1
Seeliger, H1
Tympner, KD1
Tümbay, E1

Reviews

2 reviews available for flucytosine and Central Nervous System Diseases

ArticleYear
Treatment of fungal infections of the central nervous system.
    Annals of neurology, 1981, Volume: 9, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Central Nervous System Diseases; Chemical Phenomena; Chemistry; F

1981
Diagnosis of cryptococcosis and monitoring of chemotherapy.
    Mykosen, 1985, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Africa; Amphotericin B; Asia, Southeastern; Australia; Central Nervous System Dis

1985

Other Studies

8 other studies available for flucytosine and Central Nervous System Diseases

ArticleYear
Treatment and mortality outcomes in patients with other extrapulmonary cryptococcal disease compared with central nervous system disease.
    Mycoses, 2021, Volume: 64, Issue:2

    Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Central Nervous System Diseases; Cryptococcosis; Cry

2021
Systemic Candida infections in infants in intensive care nurseries: high incidence of central nervous system involvement.
    The Journal of pediatrics, 1984, Volume: 105, Issue:4

    Topics: Amphotericin B; Candidiasis; Central Nervous System Diseases; Female; Flucytosine; Humans; Infant; I

1984
Management of central nervous system cryptococcosis.
    The Western journal of medicine, 1980, Volume: 132, Issue:2

    Topics: Amphotericin B; Brain Diseases; Central Nervous System Diseases; Cryptococcosis; Flucytosine; Humans

1980
[Cryptococcosis of the central nervous system: evaluation of amphotericin-B, 5-fluorocytosine and miconazole therapy in 18 cases].
    Arquivos de neuro-psiquiatria, 1979, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Amphotericin B; Central Nervous System Diseases; Child, Preschool; Cryptococcosis

1979
CNS cryptococcosis: unusual aspects.
    Clinical and experimental neurology, 1989, Volume: 26

    Topics: Adult; Aged; Amphotericin B; Central Nervous System Diseases; Cryptococcosis; Female; Fluconazole; F

1989
[Amphotericin B in the treatment of neurocryptococcosis in patients subjected to renal transplantation].
    Arquivos de neuro-psiquiatria, 1988, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Aged; Amphotericin B; Central Nervous System Diseases; Child; Child, Preschool; C

1988
Cryptococcal infection of the central nervous system.
    The Medical clinics of North America, 1985, Volume: 69, Issue:2

    Topics: Amphotericin B; Central Nervous System Diseases; Cryptococcosis; Flucytosine; Humans; Meningitis; Pr

1985
[Cryptococcosis of the central nervous system with cellular immune reaction disorders].
    Monatsschrift fur Kinderheilkunde, 1974, Volume: 122, Issue:7

    Topics: Antifungal Agents; Benzene Derivatives; Central Nervous System Diseases; Child; Cryptococcosis; Fema

1974