flucytosine has been researched along with Bone Cancer in 4 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary and metastatic bone cancers are difficult to eradicate and novel approaches are needed to improve treatment and extend life." | 1.33 | Osteoclasts direct bystander killing of bone cancer. ( Clohisy, DR; Donohue, JM; Goblirsch, MJ; Lynch, CM; Mathews, WE; Ramnaraine, ML, 2006) |
| "In addition, 5FC treatment of bone sarcomas caused a significant reduction in cancer-induced bone destruction (P < 0." | 1.32 | Direct and bystander killing of sarcomas by novel cytosine deaminase fusion gene. ( Clohisy, DR; Goblirsch, M; Lewis, V; Lynch, C; Mantyh, P; Orchard, P; Pan, W; Ramnaraine, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramnaraine, M | 2 |
| Pan, W | 3 |
| Goblirsch, M | 2 |
| Lynch, C | 2 |
| Lewis, V | 1 |
| Orchard, P | 1 |
| Mantyh, P | 1 |
| Clohisy, DR | 4 |
| Zwolak, P | 1 |
| Ramnaraine, ML | 2 |
| Alaei, P | 1 |
| Mathews, WE | 1 |
| Donohue, JM | 1 |
| Lynch, CM | 1 |
| Goblirsch, MJ | 1 |
4 other studies available for flucytosine and Bone Cancer
| Article | Year |
|---|---|
Direct and bystander killing of sarcomas by novel cytosine deaminase fusion gene.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cytosine Deaminase; Flucytosine; Fluorouracil; Genetic Th | 2003 |
Osteoclasts direct bystander killing of cancer cells in vitro.
Topics: Animals; Antimetabolites, Antineoplastic; Bone Marrow Cells; Bone Neoplasms; Breast Neoplasms; Cell | 2006 |
Novel cytosine deaminase fusion gene enhances the effect of radiation on breast cancer in bone by reducing tumor burden, osteolysis, and skeletal fracture.
Topics: Animals; Antimetabolites; Bone Neoplasms; Carcinoma; Combined Modality Therapy; Cytosine Deaminase; | 2006 |
Osteoclasts direct bystander killing of bone cancer.
Topics: Acid Phosphatase; Animals; Antimetabolites, Antineoplastic; Bone Neoplasms; Cell Line, Tumor; Cocult | 2006 |