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flucytosine and Blastomycosis

flucytosine has been researched along with Blastomycosis in 18 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Blastomycosis: A fungal infection that may appear in two forms: 1, a primary lesion characterized by the formation of a small cutaneous nodule and small nodules along the lymphatics that may heal within several months; and 2, chronic granulomatous lesions characterized by thick crusts, warty growths, and unusual vascularity and infection in the middle or upper lobes of the lung.

Research Excerpts

ExcerptRelevanceReference
" Two distinct eras of rapid progress in antifungal therapy followed: first, in the 1950's came the introduction of the polyenes, nystatin and pimaricin for cutaneous, vaginal and intestinal candidiasis, and amphotericin B for the treatment of severe systemic mycoses."4.76Progress in antimycotic chemotherapy 1945-1980. ( Holt, RJ, 1980)
" This case is of interest not only because of the exceptional location of the abscess in the brainstem, but also because of its treatment: this was the first case where the fluconazole-flucytosine combination was used against blastomycosis with fully satisfactory results after a 28-month follow-up."3.68[Blastomycosis localized in the brain stem]. ( Cosnefroy, JY; Dujardin, P; Ferrari, E; Gari-Toussaint, M; Lefichoux, Y; Michiels, JF; Paquis, P; Taillan, B, 1992)
"The deep mycoses are increasing in importance both as opportunistic infections and from exposure in geographically defined areas."2.37Cutaneous and mucosal manifestations of the deep mycotic infections. ( Meyer, RD, 1986)
"Although blastomycosis is endemic in North America, only 4 cases have been identified in Natal during the last 25 years, and all presented with atypical clinical features."1.28Tropical mycoses. ( Bayles, MA, 1992)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199012 (66.67)18.7374
1990's6 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stamm, AM1
Dismukes, WE1
Catanzaro, A1
Otsuka, F1
Seki, Y1
Takizawa, K1
Holt, RJ1
Berenguer Berenguer, J1
Baum, GL1
Utz, JP2
Stretcher, GS1
Smith, JG1
Cartwright, RY1
Bayles, MA1
Schaberg, T1
Lode, H1
Taillan, B2
Ferrari, E2
Cosnefroy, JY2
Gari-Toussaint, M2
Michiels, JF2
Paquis, P2
Lefichoux, Y2
Dujardin, P2
Meyer, RD1
Newberry, WM1
Abernathy, RS1

Reviews

7 reviews available for flucytosine and Blastomycosis

ArticleYear
Current therapy of pulmonary and disseminated fungal diseases.
    Chest, 1983, Volume: 83, Issue:6

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Chromoblastomycosis; C

1983
Progress in antimycotic chemotherapy 1945-1980.
    Infection, 1980, Volume: 8 Suppl 3

    Topics: Amphotericin B; Antifungal Agents; Blastomycosis; Candidiasis; Flucytosine; Humans; Imidazoles; Myco

1980
[Commonly used antifungal agents in the treatment of systemic mycoses].
    Revista clinica espanola, 1995, Volume: 195 Suppl 3

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Clinical Trials as Top

1995
Antifungal drugs.
    The Journal of antimicrobial chemotherapy, 1975, Volume: 1, Issue:2

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Blastomycosis; Candicidin; Candidiasis; C

1975
[Therapy of pulmonary mycoses].
    Deutsche medizinische Wochenschrift (1946), 1992, Nov-06, Volume: 117, Issue:45

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Blastomy

1992
Cutaneous and mucosal manifestations of the deep mycotic infections.
    Acta dermato-venereologica. Supplementum, 1986, Volume: 121

    Topics: Amphotericin B; Aspergillosis; Blastomycosis; Candidiasis; Candidiasis, Cutaneous; Coccidioidomycosi

1986
Drug treatment of the systemic mycoses.
    Seminars in drug treatment, 1972,Winter, Volume: 2, Issue:3

    Topics: Actinomycosis; Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidi

1972

Trials

1 trial available for flucytosine and Blastomycosis

ArticleYear
Antifungal therapy, 1978.
    Postgraduate medical journal, 1979, Volume: 55, Issue:647

    Topics: Amphotericin B; Antifungal Agents; Blastomycosis; Clinical Trials as Topic; Flucytosine; History, 18

1979

Other Studies

10 other studies available for flucytosine and Blastomycosis

ArticleYear
Pulmonary mycosis in pregnant women.
    Chest, 1984, Volume: 86, Issue:3 Suppl

    Topics: Adult; Amphotericin B; Blastomycosis; Coccidioides; Coccidioidomycosis; Cryptococcosis; Estradiol; F

1984
[Ultrastructural study on anti-fungal effects of 5-fluorocytosine-influences to Trichosporon cutaneum (author's transl)].
    Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology, 1981, Dec-15, Volume: 91, Issue:14

    Topics: Adult; Blastomyces; Blastomycosis; Cytosine; Dermatomycoses; Female; Flucytosine; Humans

1981
Systemic antifungal drugs.
    The Medical letter on drugs and therapeutics, 1997, Sep-12, Volume: 39, Issue:1009

    Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidom

1997
The current status of chemotherapeutic agents for the systemic mycoses.
    Contributions to microbiology and immunology, 1977, Volume: 4

    Topics: Amphotericin B; Antifungal Agents; Blastomycosis; Clotrimazole; Flucytosine; Humans; Miconazole; Myc

1977
Diagnosis and treatment of cutaneous fungus diseases.
    Disease-a-month : DM, 1975

    Topics: Actinomycosis; Amphotericin B; Blastomycosis; Candida albicans; Candidiasis, Cutaneous; Chromoblasto

1975
Tropical mycoses.
    Chemotherapy, 1992, Volume: 38 Suppl 1

    Topics: Adult; Aged; Antifungal Agents; Blastomycosis; Chromoblastomycosis; Drug Therapy, Combination; Femal

1992
[Blastomycosis localized in the brain stem].
    Presse medicale (Paris, France : 1983), 1992, Feb-08, Volume: 21, Issue:5

    Topics: Adult; Blastomyces; Blastomycosis; Brain Abscess; Brain Stem; Drug Therapy, Combination; Fluconazole

1992
Favourable outcome of blastomycosis of the brain stem with fluconazole and flucytosine treatment.
    Annals of medicine, 1992, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Blastomyces; Blastomycosis; Brain Stem; Drug Therapy, Combination; Ence

1992
Chemotherapy of the systemic mycoses.
    American family physician, 1973, Volume: 7, Issue:2

    Topics: Amphotericin B; Antifungal Agents; Blastomycosis; Coccidioidomycosis; Cryptococcosis; Flucytosine; H

1973
Treatment of systemic mycoses.
    Medicine, 1973, Volume: 52, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Cr

1973