flucytosine has been researched along with Agranulocytosis in 10 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the potential use of fluconazole for prevention and treatment of disseminated candidiasis in granulocytopenic patients, its in vivo antifungal activity was studied in three models of disseminated candidiasis in persistently granulocytopenic rabbits: acute, subacute, and chronic disseminated candidiasis." | 7.68 | Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis. ( Aoki, S; Bacher, J; Lee, J; Mechinaud, F; Pizzo, PA; Rubin, M; Walsh, TJ, 1990) |
| "To investigate the potential use of fluconazole for prevention and treatment of disseminated candidiasis in granulocytopenic patients, its in vivo antifungal activity was studied in three models of disseminated candidiasis in persistently granulocytopenic rabbits: acute, subacute, and chronic disseminated candidiasis." | 3.68 | Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis. ( Aoki, S; Bacher, J; Lee, J; Mechinaud, F; Pizzo, PA; Rubin, M; Walsh, TJ, 1990) |
| "Candidiasis was established by intravenously administering Candida albicans or Candida tropicalis (1-2 x 10(5) colony-forming units) and resulted in hepatic and splenic lesions that mimicked those associated with hepatosplenic candidiasis in humans." | 1.27 | Evaluation of single-drug and combination antifungal therapy in an experimental model of candidiasis in rabbits with prolonged neutropenia. ( Bacher, J; O'Leary, T; Pizzo, PA; Thaler, M, 1988) |
| "15 of 16 cases with septicemia at autopsy had terminal fever." | 1.26 | Causes of death in leukemia and lymphoma with modern treatment. ( Adolfsson, J; Lagerlöf, B; Lantz, B; Reizenstein, P, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lantz, B | 1 |
| Adolfsson, J | 1 |
| Lagerlöf, B | 1 |
| Reizenstein, P | 1 |
| Wise, GJ | 2 |
| Kozinn, PJ | 2 |
| Goldberg, P | 2 |
| Souhami, RL | 1 |
| Ashton, CR | 1 |
| Lee-Potter, JP | 1 |
| Nawabi, IU | 1 |
| Walsh, TJ | 1 |
| Aoki, S | 1 |
| Mechinaud, F | 1 |
| Bacher, J | 2 |
| Lee, J | 1 |
| Rubin, M | 1 |
| Pizzo, PA | 2 |
| Wolf, HH | 1 |
| Scharf, RE | 1 |
| Arning, M | 1 |
| Schneider, W | 1 |
| ter Borg, F | 1 |
| Kuijper, EJ | 1 |
| van der Lelie, H | 1 |
| Shindo, K | 1 |
| Mizuno, T | 1 |
| Matsumoto, Y | 1 |
| Hashimoto, Y | 1 |
| Matsumura, M | 1 |
| Ito, A | 1 |
| Shionoiri, H | 1 |
| Thaler, M | 1 |
| O'Leary, T | 1 |
| Muramoto, T | 1 |
| Ohi, T | 1 |
| Nishimura, K | 1 |
10 other studies available for flucytosine and Agranulocytosis
| Article | Year |
|---|---|
Causes of death in leukemia and lymphoma with modern treatment.
Topics: Agranulocytosis; Bone Marrow; Escherichia coli; Female; Flucytosine; Heart Failure; Humans; Leukemia | 1980 |
Flucytosine in the management of genitourinary candidiasis: 5 years of experience.
Topics: Agranulocytosis; Amphotericin B; Candidiasis; Cytosine; Female; Flucytosine; Genital Diseases, Femal | 1980 |
Agranulocytosis and systemic candidiasis following clomipramine therapy.
Topics: Adult; Agranulocytosis; Candidiasis; Clomipramine; Depression; Dibenzazepines; Female; Flucytosine; | 1976 |
Agranulocytosis associated with flucytosine for urinary candidiasis.
Topics: Aged; Agranulocytosis; Candidiasis; Cytosine; Cytotoxicity Tests, Immunologic; Drug Hypersensitivity | 1976 |
Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis.
Topics: Acute Disease; Agranulocytosis; Amphotericin B; Animals; Candidiasis; Chronic Disease; Disease Model | 1990 |
Preliminary results of treatment with itraconazole in patients with systemic fungal infections.
Topics: Acute Disease; Adult; Agranulocytosis; Antifungal Agents; Antineoplastic Agents; Drug Evaluation; Dr | 1990 |
Fatal mucormycosis presenting as an appendiceal mass with metastatic spread to the liver during chemotherapy-induced granulocytopenia.
Topics: Adult; Agranulocytosis; Amphotericin B; Appendix; Cecal Diseases; Female; Flucytosine; Humans; Injec | 1990 |
Granulocytopenia and thrombocytopenia associated with combination therapy of amphotericin B and low-dose flucytosine in a patient with cryptococcal meningitis.
Topics: Adult; Agranulocytosis; Amphotericin B; Cryptococcosis; Drug Therapy, Combination; Flucytosine; Huma | 1989 |
Evaluation of single-drug and combination antifungal therapy in an experimental model of candidiasis in rabbits with prolonged neutropenia.
Topics: Agranulocytosis; Amphotericin B; Animals; Antifungal Agents; Candidiasis; Cytarabine; Drug Evaluatio | 1988 |
[Case of autoimmune hemolytic anemia complicated by cryptococcal meningitis during therapy of neutropenia].
Topics: Agranulocytosis; Amphotericin B; Anemia, Hemolytic, Autoimmune; Cryptococcosis; Female; Flucytosine; | 1988 |