Page last updated: 2024-10-27

flucytosine and Acute Kidney Failure

flucytosine has been researched along with Acute Kidney Failure in 12 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Research Excerpts

ExcerptRelevanceReference
" Flucytosine undergoes extensive renal elimination; however, optimal dosing in patients with renal impairment, or those requiring renal replacement therapy (RRT), is not well-established."1.62Therapeutic drug monitoring of flucytosine in a cardiac transplant patient receiving continuous veno-venous hemofiltration and intermittent hemodialysis: A case report. ( Adamsick, ML; Bidell, MR; Elshaboury, RH; Gandhi, RG; Kotton, CN; Roberts, MB; Williams, KN, 2021)
" Serum drug concentration determination is necessary to devise an optimal dosage regimen for the patient."1.29Elimination of flucytosine by continuous hemofiltration. ( Kronfol, NO; Lau, AH, 1995)
"albicans infection in patients with acute renal failure are described."1.27Systemic and disseminated candidiasis complicating acute renal failure. ( Green, AD; Masterton, RG; Rainford, DJ; Stevens, PE, 1988)
" We found a linear relationship between the elimination rate constant and the FR, and based on these data, a dosage schedule is proposed regarding the use of 5-FC in patients treated with CH."1.275-Fluorocytosine kinetics in patients with acute renal failure undergoing continuous hemofiltration. ( Glöckner, WM; Ittel, TH; Legler, UF; Polak, A; Sieberth, HG, 1987)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Williams, KN1
Bidell, MR1
Adamsick, ML1
Elshaboury, RH1
Roberts, MB1
Kotton, CN1
Gandhi, RG1
Poenaru, SM1
Rofaiel, R1
Hosseini-Moghaddam, SM1
Wang, L1
Tang, Y1
Howell, DN1
Ruiz, P1
Spurney, RF1
Biyikli, NK1
Tugtepe, H1
Akpinar, I1
Alpay, H1
Ozek, E1
Baley, JE1
Kliegman, RM1
Fanaroff, AA1
Lau, AH1
Kronfol, NO1
Staib, F1
Bennhold, I1
Voigt, HW1
Bangel, C1
Blisse, A1
Stevens, PE1
Rainford, DJ1
Green, AD1
Masterton, RG1
Ittel, TH1
Legler, UF1
Polak, A1
Glöckner, WM1
Sieberth, HG1
Rodicio, JL1
Ortuño, MT1
Alés, JM1
Hernando, L1
Drouhet, E2
Babinet, P2
Chapusot, JP1
Kleinknecht, D2
Ganeval, D1
Schortgen, E1

Reviews

1 review available for flucytosine and Acute Kidney Failure

ArticleYear
The longest use of liposomal amphotericin B and 5-fluorocytosine in neonatal renal candidiasis.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:7

    Topics: Acute Kidney Injury; Amphotericin B; Antifungal Agents; Candidiasis; Female; Flucytosine; Humans; In

2004

Other Studies

11 other studies available for flucytosine and Acute Kidney Failure

ArticleYear
Therapeutic drug monitoring of flucytosine in a cardiac transplant patient receiving continuous veno-venous hemofiltration and intermittent hemodialysis: A case report.
    Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:4

    Topics: Acute Kidney Injury; Continuous Renal Replacement Therapy; Drug Monitoring; Female; Flucytosine; Hea

2021
    BMJ case reports, 2017, Oct-11, Volume: 2017

    Topics: Abscess; Acute Kidney Injury; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Flucytosin

2017
A novel mouse model of podocyte depletion.
    Nephron. Experimental nephrology, 2012, Volume: 121, Issue:1-2

    Topics: Acute Kidney Injury; Animals; Antimetabolites; Cytosine Deaminase; Disease Models, Animal; Flucytosi

2012
Disseminated fungal infections in very low-birth-weight infants: therapeutic toxicity.
    Pediatrics, 1984, Volume: 73, Issue:2

    Topics: Acute Kidney Injury; Amphotericin B; Cytosine; Flucytosine; Humans; Infant; Infant, Low Birth Weight

1984
Elimination of flucytosine by continuous hemofiltration.
    American journal of nephrology, 1995, Volume: 15, Issue:4

    Topics: Acute Kidney Injury; Adolescent; Antifungal Agents; Candidiasis; Flucytosine; Hemofiltration; Humans

1995
[Amphotericin B and flucytosine therapy of Aspergillus pneumonia and acute renal failure].
    Klinische Wochenschrift, 1987, Jan-05, Volume: 65, Issue:1

    Topics: Acute Kidney Injury; Amphotericin B; Aspergillosis; Aspergillus flavus; Aspergillus fumigatus; Combi

1987
Systemic and disseminated candidiasis complicating acute renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1988, Volume: 3, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Amphotericin B; Candidiasis; Catheters, Indwelling; Drainage; Fema

1988
5-Fluorocytosine kinetics in patients with acute renal failure undergoing continuous hemofiltration.
    Chemotherapy, 1987, Volume: 33, Issue:2

    Topics: Acute Kidney Injury; Adult; Blood; Female; Flucytosine; Humans; Kinetics; Male; Middle Aged; Ultrafi

1987
[Treatment of sepsis by Candida in renal patients with 5-fluorocytosine].
    Revista clinica espanola, 1974, Sep-30, Volume: 134, Issue:6

    Topics: Acute Kidney Injury; Adult; Candidiasis; Cholecystectomy; Cholelithiasis; Cytosine; Diabetic Coma; D

1974
5-Fluorocytosine in the treatment of candidiasis with acute renal insufficiency: its kinetics during haemodialysis and peritoneal dialysis.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Sep-20, Volume: 19, Issue:9

    Topics: Acute Kidney Injury; Antifungal Agents; Anuria; Biotransformation; Candidiasis; Cytosine; Diuresis;

1973
[5 fluorocytosine in the treatment of candidiasis with acute kidney failure].
    Journal d'urologie et de nephrologie, 1973, Volume: 79, Issue:9

    Topics: Acute Kidney Injury; Adult; Antifungal Agents; Candidiasis; Cytosine; Flucytosine; Humans; Renal Dia

1973