flucytosine has been researched along with Abnormalities, Drug-Induced in 2 studies
Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the abnormalities that are specific to administration of flucytosine at one time point during embryonic organogenesis, flucytosine was administered orally to pregnant Sprague Dawley (SD) rats in a single dose on day 11 of pregnancy at 25 or 35 mg/kg." | 3.91 | Developmental toxicity of flucytosine following administration to pregnant rats at a specific time point of organogenesis. ( Fujii, S; Furukawa, M; Horimoto, M; Itoh, K; Kariwano-Kimura, Y; Matsuura, M; Yabe, K, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, S | 1 |
| Yabe, K | 1 |
| Kariwano-Kimura, Y | 1 |
| Furukawa, M | 1 |
| Itoh, K | 1 |
| Matsuura, M | 1 |
| Horimoto, M | 1 |
| Kuwagata, M | 1 |
| Senuma, M | 1 |
| Todoroki, M | 1 |
| Kumagai, F | 1 |
| Kumamoto, T | 1 |
| Ogawa, T | 1 |
2 other studies available for flucytosine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Developmental toxicity of flucytosine following administration to pregnant rats at a specific time point of organogenesis.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Drug Administration Schedule; Eating; Ec | 2019 |
Induction of a thoracolumbar supernumerary rib in rat developmental toxicity studies: A short discussion on the critical window.
Topics: Abnormalities, Drug-Induced; Animals; Fetus; Flucytosine; Humans; Musculoskeletal Abnormalities; Rat | 2019 |