fluconazole has been researched along with Torsade de Pointes in 17 studies
Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present the occurrence of 'torsade de pointes' induced by the combination of peroperative fluconazole administration and sevoflurane anesthesia in a patient with 'long QT syndrome' (LQTS) scheduled for resection of a sacral abscess." | 7.77 | Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report. ( Bracke, FA; Tacken, MC; Van Zundert, AA, 2011) |
| "This case report describes the successful management of a patient with diabetic ketoacidosis, who developed torsades de pointes leading to nine cardiac arrests secondary to intravenous fluconazole administration on a background of hypokalaemia and hypocalcaemia." | 7.75 | Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests. ( Arora, MK; Chakravarty, C; Singh, PM; Trikha, A, 2009) |
| "We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide." | 7.73 | Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy. ( Kobayashi, M; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A; Tobita, T, 2006) |
| "To present a case of fluconazole-associated torsade de pointes (TDP) and discuss fluconazole's role in causing TDP." | 7.71 | Fluconazole-induced torsade de pointes. ( Hanley, JF; Merliss, AD; Potti, A; Tholakanahalli, VN, 2001) |
| "Fluconazole was discontinued at this time, and liposomal amphotericin B was resumed." | 5.35 | Torsades de pointes in a patient receiving fluconazole for cerebral cryptococcosis. ( Grayson, ML; McMahon, JH, 2008) |
| "We present the occurrence of 'torsade de pointes' induced by the combination of peroperative fluconazole administration and sevoflurane anesthesia in a patient with 'long QT syndrome' (LQTS) scheduled for resection of a sacral abscess." | 3.77 | Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report. ( Bracke, FA; Tacken, MC; Van Zundert, AA, 2011) |
| "This case report describes the successful management of a patient with diabetic ketoacidosis, who developed torsades de pointes leading to nine cardiac arrests secondary to intravenous fluconazole administration on a background of hypokalaemia and hypocalcaemia." | 3.75 | Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests. ( Arora, MK; Chakravarty, C; Singh, PM; Trikha, A, 2009) |
| "We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide." | 3.73 | Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy. ( Kobayashi, M; Naito, K; Nakamura, S; Ohnishi, K; Ohno, R; Sahara, N; Shigeno, K; Shinjo, K; Takeshita, A; Tobita, T, 2006) |
| "To present a case of fluconazole-associated torsade de pointes (TDP) and discuss fluconazole's role in causing TDP." | 3.71 | Fluconazole-induced torsade de pointes. ( Hanley, JF; Merliss, AD; Potti, A; Tholakanahalli, VN, 2001) |
| "Fluconazole is an antifungal medication that has been reported to cause prolongation of the QT interval and Torsades de Pointes (TdP) ventricular tachycardia in adults." | 1.35 | Torsades de Pointes ventricular tachycardia in a pediatric patient treated with fluconazole. ( Esch, JJ; Kantoch, MJ, 2008) |
| "Fluconazole was discontinued at this time, and liposomal amphotericin B was resumed." | 1.35 | Torsades de pointes in a patient receiving fluconazole for cerebral cryptococcosis. ( Grayson, ML; McMahon, JH, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Ünal Yüksekgönül, A | 1 |
| Ertuğrul, İ | 1 |
| Karagöz, T | 1 |
| De Puy, F | 1 |
| Kay, GN | 1 |
| Tilton, JJ | 1 |
| Sadr, R | 1 |
| Groo, VL | 1 |
| Chakravarty, C | 1 |
| Singh, PM | 1 |
| Trikha, A | 1 |
| Arora, MK | 1 |
| Tacken, MC | 1 |
| Bracke, FA | 1 |
| Van Zundert, AA | 1 |
| Zeuli, JD | 1 |
| Wilson, JW | 1 |
| Estes, LL | 1 |
| Khazan, M | 1 |
| Mathis, AS | 1 |
| Gandhi, PJ | 1 |
| Menezes, PA | 1 |
| Vu, HT | 1 |
| Rivera, AL | 1 |
| Ramaswamy, K | 1 |
| Hrovatin, E | 1 |
| Zardo, F | 1 |
| Brieda, M | 1 |
| Dametto, E | 1 |
| Piazza, R | 1 |
| Antonini-Canterin, F | 1 |
| Cassin, M | 1 |
| Meneguzzo, N | 1 |
| Viel, E | 1 |
| Lestuzzi, C | 1 |
| Di Gennaro, G | 1 |
| Nicolosi, GL | 1 |
| Tatetsu, H | 1 |
| Asou, N | 1 |
| Nakamura, M | 1 |
| Hanaoka, N | 1 |
| Matsuno, F | 1 |
| Horikawa, K | 1 |
| Mitsuya, H | 1 |
| Hinterseer, M | 1 |
| Irlbeck, M | 1 |
| Ney, L | 1 |
| Beckmann, BM | 1 |
| Pfeufer, A | 1 |
| Steinbeck, G | 1 |
| Kaab, S | 1 |
| Naito, K | 1 |
| Kobayashi, M | 1 |
| Sahara, N | 1 |
| Shigeno, K | 1 |
| Nakamura, S | 1 |
| Shinjo, K | 1 |
| Tobita, T | 1 |
| Takeshita, A | 1 |
| Ohno, R | 1 |
| Ohnishi, K | 1 |
| Esch, JJ | 1 |
| Kantoch, MJ | 1 |
| McMahon, JH | 1 |
| Grayson, ML | 1 |
| Wassmann, S | 1 |
| Nickenig, G | 1 |
| Böhm, M | 1 |
| Dorsey, ST | 1 |
| Biblo, LA | 1 |
| Tholakanahalli, VN | 1 |
| Potti, A | 1 |
| Hanley, JF | 1 |
| Merliss, AD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Tamoxifen Combined With Amphotericin B and Fluconazole for Cryptococcal Meningitis[NCT03112031] | Phase 2 | 50 participants (Actual) | Interventional | 2017-10-10 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluconazole and Torsade de Pointes
| Article | Year |
|---|---|
Probable case of torsades de pointes induced by fluconazole.
Topics: Adult; Aged; Electrocardiography; Female; Fluconazole; Humans; Middle Aged; Risk Factors; Torsades d | 2002 |
16 other studies available for fluconazole and Torsade de Pointes
| Article | Year |
|---|---|
Fluconazole-associated QT interval prolongation and Torsades de Pointes in a paediatric patient.
Topics: Adolescent; Child; Electrocardiography; Female; Fluconazole; Humans; Long QT Syndrome; Tachycardia, | 2021 |
Electrocardiogram Challenge Syncope in a Woman With Nausea and Diarrhea.
Topics: Aged; Cholecalciferol; Clonazepam; Diarrhea; Esomeprazole; Female; Fluconazole; Humans; Nausea; Onda | 2017 |
Concomitant use of levofloxacin and fluconazole leading to possible torsades de pointes.
Topics: Adult; Electrocardiography; Female; Fluconazole; Humans; Levofloxacin; Long QT Syndrome; Risk Factor | 2019 |
Fluconazole-induced recurrent ventricular fibrillation leading to multiple cardiac arrests.
Topics: Adult; Antifungal Agents; Diabetic Ketoacidosis; Female; Fluconazole; Heart Arrest; Humans; Hypocalc | 2009 |
Torsade de pointes during sevoflurane anesthesia and fluconazole infusion in a patient with long QT syndrome. A case report.
Topics: Abscess; Aged; Anesthetics, Inhalation; Antifungal Agents; Electrocardiography; Female; Fluconazole; | 2011 |
Effect of combined fluoroquinolone and azole use on QT prolongation in hematology patients.
Topics: Adult; Aged; Antifungal Agents; Drug Administration Schedule; Drug Therapy, Combination; Electrocard | 2013 |
Fluconazole- and levofloxacin-induced torsades de pointes in an intensive care unit patient.
Topics: Anti-Infective Agents; Antifungal Agents; Fluconazole; Humans; Intensive Care Units; Levofloxacin; M | 2003 |
[Long QT and torsade de pointes in a patient with acquired human immunodeficiency virus infection in multitherapy with drugs affecting cytochrome P450].
Topics: Acquired Immunodeficiency Syndrome; Analgesics, Opioid; Antifungal Agents; Antiretroviral Therapy, H | 2004 |
Torsades de pointes upon fluconazole administration in a patient with acute myeloblastic leukemia.
Topics: Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Female; Fluconazole; Humans; Leuk | 2006 |
Acute respiratory distress syndrome with transiently impaired left ventricular function and Torsades de Pointes arrhythmia unmasking congenital long QT syndrome in a 25-yr-old woman.
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Echocardiography; ERG1 Potassium Channel; Erythromy | 2006 |
Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy.
Topics: Adult; Anthracyclines; Antifungal Agents; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Cardi | 2006 |
Torsades de Pointes ventricular tachycardia in a pediatric patient treated with fluconazole.
Topics: Antifungal Agents; Candidiasis; Child; Electrocardiography; Fluconazole; Heart Conduction System; Hu | 2008 |
Torsades de pointes in a patient receiving fluconazole for cerebral cryptococcosis.
Topics: Aged; Antifungal Agents; Fatal Outcome; Female; Fluconazole; Humans; Meningitis, Cryptococcal; Risk | 2008 |
Long QT syndrome and torsade de pointes in a patient receiving fluconazole.
Topics: Antifungal Agents; Female; Fluconazole; Humans; Long QT Syndrome; Middle Aged; Torsades de Pointes | 1999 |
Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antifungal Agents; Drug Interactions; Electrocardio | 2000 |
Fluconazole-induced torsade de pointes.
Topics: Aged; Antifungal Agents; Candidiasis; Diverticulitis; Electrocardiography; Female; Fluconazole; Huma | 2001 |