Page last updated: 2024-10-27

fluconazole and Stillbirth

fluconazole has been researched along with Stillbirth in 7 studies

Fluconazole: Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
fluconazole : A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis.

Stillbirth: The event that a FETUS is born dead or stillborn.

Research Excerpts

ExcerptRelevanceReference
"While topical azoles are the first-line treatment for fungal infections, oral fluconazole is frequently used during pregnancy."7.91Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case-control studies. ( Abrahamowicz, M; Bérard, A; Bernatsky, S; de Moura, CS; Gorgui, J; Sheehy, O; Zhao, JP, 2019)
"To study the association between oral fluconazole exposure during pregnancy and the risk of spontaneous abortion and stillbirth."7.83Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth. ( Hviid, A; Melbye, M; Mølgaard-Nielsen, D; Pasternak, B; Svanström, H, 2016)
" The oral antifungal agents used during pregnancy were fluconazole and itraconazole."5.05Fetal outcomes after maternal exposure to oral antifungal agents during pregnancy: A systematic review and meta-analysis. ( Liu, D; Wu, L; Zhang, C; Zhang, L, 2020)
"While topical azoles are the first-line treatment for fungal infections, oral fluconazole is frequently used during pregnancy."3.91Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case-control studies. ( Abrahamowicz, M; Bérard, A; Bernatsky, S; de Moura, CS; Gorgui, J; Sheehy, O; Zhao, JP, 2019)
"To study the association between oral fluconazole exposure during pregnancy and the risk of spontaneous abortion and stillbirth."3.83Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth. ( Hviid, A; Melbye, M; Mølgaard-Nielsen, D; Pasternak, B; Svanström, H, 2016)
"Fluconazole is a bis-triazole agent used in the treatment of superficial and systemic fungal infections, with vaginal candidiasis being one of the commonest indications to fluconazole treatment."2.72Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature. ( Budani, MC; Di Marzio, M; Fensore, S; Tiboni, GM, 2021)
"Fluconazole (FLCZ) is an azole antifungal agent and it has shown excellent clinical activities in suppressing fungemia with Candida albicans after hematopoietic stem cell transplantation."1.48Breakthrough Candida guilliermondii (Meyerozyma guilliermondii) fungemia after cord blood transplantation for extranodal NK-cell lymphoma with azole prophylaxis. ( Ishida, F; Ito, T; Kikuchi, K; Nakazawa, H; Nishina, S; Sakai, H; Senoo, Y, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Liu, D1
Zhang, C1
Wu, L1
Zhang, L2
Budani, MC1
Fensore, S1
Di Marzio, M1
Tiboni, GM1
Nakazawa, H1
Nishina, S1
Senoo, Y1
Sakai, H1
Ito, T1
Kikuchi, K1
Ishida, F1
Pasternak, B2
Wintzell, V1
Furu, K1
Engeland, A1
Neovius, M1
Stephansson, O1
Bérard, A1
Sheehy, O1
Zhao, JP1
Gorgui, J1
Bernatsky, S1
de Moura, CS1
Abrahamowicz, M1
Wise, J1
Mølgaard-Nielsen, D1
Svanström, H1
Melbye, M1
Hviid, A1

Reviews

2 reviews available for fluconazole and Stillbirth

ArticleYear
Fetal outcomes after maternal exposure to oral antifungal agents during pregnancy: A systematic review and meta-analysis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2020, Volume: 148, Issue:1

    Topics: Abortion, Spontaneous; Antifungal Agents; Case-Control Studies; Cohort Studies; Congenital Abnormali

2020
Maternal use of fluconazole and congenital malformations in the progeny: A meta-analysis of the literature.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 100

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Antifungal Agents; Candidiasis, Vulvovaginal; Do

2021

Other Studies

5 other studies available for fluconazole and Stillbirth

ArticleYear
Breakthrough Candida guilliermondii (Meyerozyma guilliermondii) fungemia after cord blood transplantation for extranodal NK-cell lymphoma with azole prophylaxis.
    Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:4

    Topics: Adult; Antibiotic Prophylaxis; Antifungal Agents; Candida; Candidemia; Candidiasis, Invasive; Cord B

2018
Oral Fluconazole in Pregnancy and Risk of Stillbirth and Neonatal Death.
    JAMA, 2018, 06-12, Volume: 319, Issue:22

    Topics: Administration, Oral; Antifungal Agents; Cohort Studies; Female; Fluconazole; Humans; Infant, Newbor

2018
Associations between low- and high-dose oral fluconazole and pregnancy outcomes: 3 nested case-control studies.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2019, 02-19, Volume: 191, Issue:7

    Topics: Abortion, Spontaneous; Administration, Oral; Adolescent; Adult; Antifungal Agents; Candidiasis, Vulv

2019
Oral antifungal is associated with increased risk of miscarriage.
    BMJ (Clinical research ed.), 2016, Jan-06, Volume: 352

    Topics: Abortion, Spontaneous; Antifungal Agents; Female; Fluconazole; Humans; Pregnancy; Stillbirth

2016
Association Between Use of Oral Fluconazole During Pregnancy and Risk of Spontaneous Abortion and Stillbirth.
    JAMA, 2016, Jan-05, Volume: 315, Issue:1

    Topics: Abortion, Spontaneous; Administration, Oral; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Ca

2016